Beth standing in front of her Poster with a coffee looking happy and well caffeinated. The poster features her work on chemically tunable permeability of engineered alpha-Hemolysin in synthetic membranes

Really enjoyed the 77th #MosbacherKolloquium ! Thanks to the organizers @gbmev.bsky.social for putting together such an amazing program and for giving me the chance to present my poster. To quote André Nadler: Membranes are great, science is great, and let's continue making discoveries! ;)

Just realized, that I have never posted my artwork on bluesky! So here are some of my favorite pieces I got to create during my PhD for different projects from @mpimicrobiomarburg.bsky.social What a journey it has been :)

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Very excited to finally share my PhD paper, about advancing #chloroplast #synbio through high-throughput plastome engineering of #Chlamydomonas.
Huge thanks to the whole team!
www.nature.com/articles/s41...

Oh no!

With this, the last bit of my PhD at @embl.org is finally out!
We developed salad (sparse all-atom denoising), a family of blazing fast protein structure diffusion models.
Paper: nature.com/articles/s42256-…
Code: github.com/mjendrusch/salad
Data: zenodo.org/records/14711580
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Just submitted my PhD thesis. Feeling kinda empty now...

Modular Engineering of Thermo-Responsive Allosteric Proteins Thermogenetics enables non-invasive spatiotemporal control over protein activity in living cells and tissues, yet its applications have largely been restricted to transcriptional regulation and membra...

www.biorxiv.org/content/10.1...

Excited to share a main project from my PhD, out now in
@naturecomms.bsky.social! 📝
We've designed and brought to life the “CORE cycle” – a new-to-nature pathway that provides a novel route for biological CO2 capture 🦠🌱
nature.com/articles/s41...
Take a look! Thread below... 🧵

Thrilled to have been part of the 76th Mosbacher Kolloquium! Huge thanks to @gbmev.bsky.social for organizing such an engaging conference! @anastasiagtz.bsky.so and I were excited to share our insights on differential transport across membranes, and we're truly honored to receive the poster award!

Computation-aided designs enable developing auxotrophic metabolic sensors for wide-range glyoxylate and glycolate detection - Nature Communications Auxotrophic metabolic sensors (AMS) are vital for bioengineering but are often time-consuming to develop. Here, the authors present a workflow for designing versatile AMS, demonstrating their use for ...

Really happy to share that our work on constructing six glyoxylate / glycolate sensors covering a three order of magnitude concentration range is out now in Nature Communications ! 🔥

Read below to see how we developed the sensors and what they are good for 🥳.

www.nature.com/articles/s41...

One-carbon fixation via the synthetic reductive glycine pathway exceeds yield of the Calvin cycle - Nature Microbiology An engineered one-carbon-fixation pathway increases biomass yields of Cupriavidus necator compared with the Calvin cycle and can support future, sustainable bio-based production.

Super excited to see my main PhD project finally out in @naturemicrobiol.bsky.social www.nature.com/articles/s41.... We show for the first time that a synthetic and engineered pathway can indeed exceed nature at one-carbon fixation.

Marburg. Sometimes it feels like I am working at Silent Hill. But it has its own charm ;)

Five generated protein structures coloured with a gradient from purple to teal. The structures are shaped and positioned to spell out the word "salad" – the name of the software described in the mentioned preprint – in all-capital letters.

New protein ML preprint from my PhD project.
We describe salad (sparse all-atom denoising), a family of efficient protein structure diffusion models and show that it works well on a bunch of protein design task previously described in the literature.

Preprint: www.biorxiv.org/content/10.1...

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