Game of microbes: a wildling’s guide Laboratory mice housed under specific pathogen-free conditions are the standard model in biomedical research. However, frequent germ-free rederivation and barrier housing restrict microbial exposure and interactions with commensal and pathogenic microorganisms. In contrast, wild mice encounter diverse microbial environments, undergo natural selection, and rely on robust immune responses for survival. Consequently, lifelong microbial exposure is a key driver in shaping mammalian physiology, establishing the need for naturalizing rodent models in biomedical research. By defining the concepts of ‘microbial self’ and ‘microbial nonself’, we propose a four-step guide for establishing a multigenerational wildling colony that accounts for both microbial self and microbial nonself. This reestablishes the common biological link shared by all free-living mammals, thereby improving the comparability between murine and human studies.

Game of microbes: a wildling’s guide

Game of microbes: a wildling’s guide Laboratory mice housed under specific pathogen-free conditions are the standard model in biomedical research. However, frequent germ-free rederivation and barrier housing restrict microbial exposure a...

Please share! Ever wondered how to establish and maintain wildlings – and why they matter? Our new paper “Game of microbes: a wildling ’s guide” is now out in Trends in Microbiology dlvr.it/TRl1Zs - Thread below with key previous work
@cp-trendsmicrobiol.bsky.social @cellpress.bsky.social @FAU.de

How birds detect Earth’s magnetic field

This study suggest a model whereby electromagnetic input from the semicircular canals activates a vestibular-mesopallial circuit in the pigeon brain

www.science.org/doi/10.1126/...

BBC Radio 4 - In Our Time, Archaea How a discovery in the 1970s changed the theory of the origin of complex life on earth.

Archaea hit prime time: www.bbc.co.uk/programmes/m...

Será un placer estar el 11 de mayo en mi ciudad, Madrid, para hablar sobre:
“Explorando la intersección cerebro-microbioma: claves para una salud integral”
Gracias @fundacionareces.bsky.social @sebbm.bsky.social por la invitación.
¡Nos vemos allí!

Natural daylight during office hours improves glucose control and whole-body substrate metabolism Harmsen et al. compared the metabolic impact of natural daylight vs. artificial office lighting in individuals with type 2 diabetes over 5 days. Daylight improved glucose homeostasis, whole-body fat u...

www.cell.com/cell-metabol...

So happy to see this beautiful poster for our upcoming Winter Concert with the Fleischmann Choir on December 7th at the Church of the Descent of the Holy Spirit in Cork.

www.tickettailor.com/events/corko...

¡Qué merecido Premio Princesa de Asturias, para el maravilloso y genial maestro, Eduardo Mendoza!

Interested in the heterogeneity of blood vessels in the CNS? Here we review the unique features of the spinal cord vasculature, its barrier properties and neurovascular interactions, highlighting unknown aspects and future research directions.
@CRC1366
@erc.europa.eu @immunosens.bsky.social

A privilege to chair symposium ‘Vascular function and cognitive health across the lifespan’ symposium today at @ecnp.eu
Thanks to speakers @vcoelhosantoslab.bsky.social Amanda Kiliaan, @mariangelesmoro.bsky.social and @blacoste.bsky.social for their fantastic presentations.
#ECNP2025

🧠🌸 How does menopause affect the mind?
This Educational Update Session is exploring the connections between menopause, cognition, and mental health.

#ECNP2025 #BrainHealth #MentalWellbeing #MenopauseResearch @oliviafoleary.bsky.social

Great to join the @network-alba.bsky.social session on Diversity and Inclusion at #ECNP2025 today!

What is the best brain to study disorders of behavior? Great discussion at @ecnp.eu moderated by @jatinnagpal.bsky.social with inputs from @ribeirocarlitos.bsky.social @emreyaksi.bsky.social @eknapska.bsky.social & Hannah Clarke #ecnp2025

Looking forward to chairing this exciting symposium at @ecnp.eu Congress Amsterdam: Vascular function and cognitive health across the lifespan. Join us to hear from these excellent speakers on how vascular health shapes cognitive function.
🗓 Tuesday, October 14th | 08:40–10:00
📍 Elicium 1
#ECNP2025

Jane Goodall’s legacy: three ways she changed science Nature - The primatologist challenged what it meant to be a scientist.

Jane Goodall, known for her pioneering work with chimpanzees, has passed away aged 91

go.nature.com/46QHIZk

Jane Goodall, my ultimate hero, always inspiring, groundbreaking, kind and wise. The world will miss you, but never forget you.

The multiomics blueprint of the individual with the most extreme lifespan In brief, Santos-Pujol and colleagues characterize the multiomics landscape of the human with the most extreme longevity. The study enables the association of advantageous genetic variants, an engaged...

www.cell.com/cell-reports...

Very excited to participate in my first concert with the marvelous #FleischmannChoir
🎶 Free admission at @mtu.ie #CorkSchoolOfMusic come join us

Really enjoyed talking about #Barriers at #Neurogastro2025 in London and meeting excellent colleagues!
@apcmicrobiomeirel.bsky.social @uccresearch.bsky.social

Congrats Kevin!!!

Last few places available to attend our Evidence for Policy Summit in Dublin next week. Visit: www.yai.ie for sign up details. If you can't attend in person, email yai@ria.ie for livestream details! #evidenceforpolicy #youngacademyireland #EfP25 @emmaefarrell.bsky.social @karinadoorley.bsky.social

Longer wavelengths in sunlight pass through the human body and have a systemic impact which improves vision - Scientific Reports Scientific Reports - Longer wavelengths in sunlight pass through the human body and have a systemic impact which improves vision

www.nature.com/articles/s41...

Blood, sweat, and beers: investigating mosquito biting preferences amidst noise and intoxication in a cross-sectional cohort study at a large music festival Introduction We live in a world split between mosquito magnets and those lucky enough to remain (nearly) untouched. The reasons why some people attract more mosquito bites than others remain largely m...

www.biorxiv.org/content/10.1...

Missing the Castilian landscape

El sedentarismo es el enemigo de un cerebro sano: 'El cerebro en movimiento', de José Luis Trejo @jltrejoneuro.bsky.social y Coral Sanfeliu. Colección #QuéSabemosDe coeditada con @CSIC.es @csicdivulga.bsky.social buff.ly/pQIa0pf

The microbiota modulates the positive impact of moderate physical exercise on memory. @CintadoElisa @JLTrejo2 @csicdivulga.bsky.social @institutocajal.bsky.social @SENC_ @isen_gard @jfcryan @Pharmabiotic cajal.csic.es/en/the-microbi…

Orgullosa de haber participado en este estudio con @jltrejoneuro.bsky.social @cintadoelisa.bsky.social @jfcryan.bsky.social @institutocajal.bsky.social demostrando que la microbiota intestinal es clave para modular los beneficios del ejercicio en la memoria y neurogénesis. @ebiomedicine.bsky.social

Excited to share our latest paper! At @institutocajal.bsky.social under @jltrejoneuro.bsky.social supervision, in collaboration with @maburto.bsky.social & @jfcryan.bsky.social . Moderate exercise boosts memory & neurogenesis in mice via gut microbiome 🏃‍♀️🧠🦠. doi.org/10.1016/j.eb...

Gut microbiota regulates exercise-induced hormetic modulation of cognitive function These findings suggest that the hormetic effects of physical exercise on cognitive function and neurogenesis are mediated by corresponding changes in the gut microbiota, highlighting a novel mechanist...

Gut microbiota regulates exercise-induced hormetic modulation of cognitive function - eBioMedicine www.thelancet.com/journals/ebi...

A diverse and distinct microbiome inside living trees - Nature Microbiome analyses of living trees show that a single tree can host approximately one trillion bacteria, with microbial communities distinctly partitioned between heartwood and sapwood and with minim...

www.nature.com/articles/s41...