More than 50 researchers joined us yesterday for our #adhesionGPCR targets workshop! Thanks to all who participated to help us prioritize targets & design purpose-built #Abs.

Interested in joining future workshops on #glialcellphenotyping & #synapticcleftsignaling? Get updates ➡️ buff.ly/9uAso7K

New integrin antibodies targeting integrin beta 1 and beta 2 just joined the IPI collections 🧪

These recombinant monoclonals recognize human targets, do not cross-react with other protein family members and are recommended for flow cytometry.

Order now: buff.ly/VpcxzlC

IPI Events & Programs Newsletter Sign up to receive news and updates on IPI educational events and programs.

We’re excited to welcome alumni from Just A Start’s Biotechnology Careers Program to a 2-day automation course next week, made possible through support from the Mass Life Sciences Center Pathmaker program! More soon 🔬

Sign up for updates on future courses ⬇️

Stanford researcher Stephen Quake imagines IPI as a modern-day Library of Alexandria, preserving and activating protein knowledge to influence how a whole new generation of therapies will be made. That’s why he’s joined forces as part of our Board of Directors.

Learn more: buff.ly/PmIpnht

#Robo3 antibodies are crucial for detecting the Roundabout Guidance Receptor 3 protein & studying neuraldevelopment & #axonnavigation—but reliable #antibodies are in short supply.

IPI just released two anti-ROBO3s that might help.

Dive into the data on our product pages ➡️ buff.ly/kk4fLJJ

Codon optimization ‘bake-off’ suggests native constructs are best tool for mammalian protein expression In the world of protein production, codon optimization is generally considered the go-to method to enhance expression and increase yields. Swapping native

In a recent study, the IPI team tested 5 codon optimization schemes (including #NativeCodons) in the construction/expression of 18 neurologically relevant human & murine #glycoproteins.

See which yielded the most proteins ➡️ buff.ly/TaFaWkY

Design de proteínas: como cientistas estão criando moléculas sob medida para enfrentar grandes desafios | Science Arena A partir de modelos computacionais e IA, cientistas desenvolvem proteínas para enfrentar desafios científicos e tecnológicos

There’s a lot of hype around #AI & #proteindesign, but there are some important considerations—including how these molecules perform in laboratory conditions, says IPI's platform director André Teixeira.

Read more from Teixeira in this Science Arena article ➡️

His next big idea might emerge from something small: Stephen Quake joins IPI Board Biophysicist Stephen Quake has held many titles. He’s invented devices, developed diagnostics and launched companies. He’s won dozens of prizes and been

This former HHMI investigator and CZI leader was determined to keep exploring life’s smallest pieces in pursuit of large-scale scientific impact. So he’s returned to his Stanford lab and joined an effort to advance protein science.

Read his story: buff.ly/ciTChrs

New #Robo #Slit antibodies just joined the IPI collections 🧪 Recommended for flow, ICC and IHC, these chimeric #recombinantproteins are specific to human and mouse targets and do not cross-react with other family members.

#axonguidance #neuronalmigration

buff.ly/mtViWPa

2026 Yeast Display Technology for Antibody Discovery A five-day course in June 2026 combining lectures and hands-on laboratory sections to train participants in the core principles of yeast display technology.

📣LAST CHANCE! Applications for our 2026 yeast display course are due TODAY 📣

Come learn the basics of #yeastdisplaylibrary prep, MACS & FACS sorts, and #AI-enabled discovery in just 5 days — directly from yeast display leaders and working scientists.

Apply now! buff.ly/4Y5YvwK

Don't have a favorite part of #antibodydiscovery? Maybe you'll find it in our 5 day #yeastdisplay course this summer!

Apply now — applications close March 30th ⏲️ buff.ly/oBlGknl

New antibody release! We've expanded our catalog of synaptic cleft antibodies with @ipiproteins.bsky.social's new antibodies targeting neurexins and neuroligins. Find these and more in our IPI Collection page:

2026 Yeast Display Technology for Antibody Discovery A five-day course in June 2026 combining lectures and hands-on laboratory sections to train participants in the core principles of yeast display technology.

Exciting update: Alloy Therapeutics will be funding two scholarships to attend IPI's 5 day course on yeast display technology for antibody discovery!

The course is open to postdocs, students, faculty & industry scientists. Scholarships will go to top candidates who apply by 3/30 ⏰ buff.ly/av8zOGo

Our automation team is running a #PEGSBoston short course on May 12 for scientists looking to gain skills in automated liquid handling and see integrated systems for protein & antibody engineering in action.

Early bird registration ends March 27th & spots are limited. Check it out! buff.ly/MHgLfXV

Codon optimization ‘bake-off’ suggests native constructs are best tool for mammalian protein expression New work from IPI suggests scientists may have overestimated the value of codon optimization ...

💫Preprint alert 💫

A new IPI study suggests scientists may be overestimating the value of #codonoptimization when producing #mammalianproteins in mammalian cell lines, throwing the value of these strategies into question.

Read more: buff.ly/1vUqbTj

⚠️ ONE WEEK to apply for our yeast display course ⚠️

Join us in June to get experience designing yeast display libraries, running #MACS/#FACS sorts & discovering top antibody candidates. Apply now: buff.ly/7rqgQWz

Thanks to our sponsors Alloy Therapeutics, @twistbioscience.com & Sony Biotechnology!

Learn the ins and outs of yeast display discovery, from antigen biotinylation to antibody identification, in our 5 day summer course. Apply by March 30th! buff.ly/1pWSBdO

Our course on automated liquid handling for protein/antibody engineering is coming to #PEGSBoston on May 12, 2026. Participants will develop methods on the Opentrons Protocol Designer, operate an OT-2 & Biomek i3 and tour the IPI lab.

Spots are limited — find out more & register: buff.ly/MHgLfXV

Interested in learning the basics of #yeastdisplaytechnology and #antibodydiscovery from leaders in the field? Join us in June for our hands-on 5-day course. Spots are limited — apply now: buff.ly/zrnlPN7

From genes to dynamics: Examining brain cell types in action may reveal the logic of brain function Defining brain cell types is no longer a matter of classification alone, but of embedding their genetic identities within the dynamical organization of population activity.

This article @thetransmitter.bsky.social shows just how vital labeling tools (like IPI’s epitope tag antibodies) can be in determining the functional identity of brain cells.

Read the piece: buff.ly/Vcsim6J

Check out our protein tools: buff.ly/SzcrTp1

Find new IPI ROBO/Slit antibodies in the @addgene.bsky.social catalog!

Axon Guidance Antibody Collection For neurons to communicate, their axons must navigate precisely to their targets through a complex process known as axon guidance or neuronal migration. This pr

New antibody release!
🧪 Anti-ROBO1 [IPI-ROBO1.81]
🧪 Anti-ROBO3 [IPI-ROBO3.119]
🧪 Anti-ROBO3 [IPI-ROBO3.124]
🧪 Anti-Slit-2 [IPI-Slit2.37]

Use our recombinant monoclonals to study #axonguidance #cellmigration #tissueformation #cytoskelatalorganization, #neuronalwiring & more
buff.ly/oNye2Ky

"Antibody discovery is like a race," says IPI research associate Swethika Balasankar. Learn how to run your own discovery campaigns using #yeastdisplaytechnology at our hands-on course this June. Apply by March 30th! buff.ly/92wAFCo

Protein design: how scientists are creating tailor-made molecules to tackle major challenges | Science Arena Using computational models and AI, scientists are developing proteins to address scientific and technological challenges.

"AI isn't smart enough to provide the ultimate solution to a problem, but it's very good at finding alternative solutions," says André Teixeira, senior director of the IPI #antibody platform. Read more from Teixeira and others in this Science Arena rundown on #AI and #proteindesign.

Apply now for our 2026 Yeast Display Technology for Antibody Discovery course! buff.ly/KuyAKw3

Highlights include:
▪️ Lab sessions on library prep, biotinylation, MACS & FACS
▪️ Lectures on principles, applications and methods of yeast display
▪️ Seminars from invited experts on display technology

His next big idea might emerge from something small: Stephen Quake joins IPI Board Biophysicist Stephen Quake has held many titles. He’s invented devices, developed diagnostics and launched companies. He’s won dozens of prizes and been

IPI welcomes Stanford biophysicist Stephen Quake to our Board of Directors!

He brings a wealth of experience with HHMI, CZI and more, and his unique perspective will be instrumental in launching the next era of protein science.

Read more: buff.ly/9coNPo2

Multiple protein structure alignment at scale with FoldMason Protein structure is conserved beyond sequence, making multiple structural alignment (MSTA) essential for analyzing distantly related proteins. Computational prediction methods have vastly extended…

A team at Seoul National University (@martinsteinegger.bsky.social) recently introduced FoldMason @science.org—an open-source tool to compare MSTA of 1000s of proteins. We see big potential to analyze proteins w/ conserved structure & limited sequence conservation

2026 Yeast Display Technology for Antibody Discovery A five-day course in June 2026 combining lectures and hands-on laboratory sections to train participants in the core principles of yeast display technology.

Scientific progress is built on shared knowledge, accessible learning, and hands-on training. So this June we’re teaching a 5 day immersive course on the #yeastdisplay principles, applications and practical workflows that drive our #antibodydiscovery campaigns.

Apply by March 30 ⬇️
buff.ly/n8crLD0

That's right. Feel free to reach out to us at antibodies@proteininnovation.org with any additional questions!

You can find more data here:
NRXN3α - proteininnovation.org/wp-content/u...
NRXN3β - proteininnovation.org/wp-content/u...