These images show live embryos of animals (jellyfish, crustacean, worm, sea urchin, sea squirt, beetle) and one of animals closest single-celled relatives. They were captured taking advantage of fluorescent proteins localised on the outer membrane of cells, allowing us to observe cell outlines. 1/9

I'm so pleased to see this work on neural crest development out in Nature today! This was a truly fantastic collaboration with @gleesonlab.bsky.social, Keng loi (Harry) Vong and @xiaoxuyang.bsky.social. Huge thanks to everyone involved 👏 🧪🐣 #devbio

www.nature.com/articles/s41...

It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪

Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis Gene expression patterns underlie development, but their systematic detection in whole embryos has remained elusive. We introduce a whole-embryo imaging platform using multiplexed error-robust fluores...

Very happy to see this out. 👏 @yinanwan.bsky.social
Bogdan Bintu and team.
Whole-embryo spatial transcriptomics at subcellular resolution from gastrulation to organogenesis | free link Science www.science.org/eprint/5MHTM...

The molecular evolution of vertebrate organs Nature Ecology & Evolution - This Review discusses recent advances in the molecular evolution of vertebrate organs, including rates of evolution of organs and cell types, molecular mechanisms...

Our internal organs are evolutionary marvels. New technologies are transforming our understanding of the evolution of vertebrate organs. You can find more by reading here:
rdcu.be/e5EgU
#EvoBio #EvoDevo 🐟🦎🐢🦇🐊🦜

Thank you for sharing!

@armilabs.bsky.social @unimelb.edu.au @stanfordpress.bsky.social #devbio #zebrafish

New morphometric analysis tool developed by Lu et al. applied to skeletal muscle cross-sections of four different juvenile teleost fish species. Main finding: Mosaic hyperplasia, i.e., the addition of new myofibers in the deep myotome, is near-zero in the small Danionella but dramatically enhanced in the giant danio relative to the intermediate grower zebrafish, establishing this mode of hyperplasia as a main driver of skeletal muscle growth in differently sized fishes.

Beautiful work led by Yansong (Kevin) Lu on skeletal muscle growth in zebrafish, giant danio, Danionella cerebrum, and killifish. HCR, new image analysis tool, scRNA-seq, and CRISPR. New international collaborations between Uni Melbourne, NCVC/Osaka, Stanford & ARMI www.biorxiv.org/content/10.6...

We have a postdoc position available. Please forward to anyone who may be interested.

Congratulations, Hadeer 🥳

Whole-body Single-cell Spatial transcriptomic atlas of adult Danionella ~1 cm long

scRNAseq
MERFISH (500-gene)
HCR

Endothelial cell podxl+ (Fig S8)

Vascular vs Visceral mural cell (Fig S10)

Peter Reddien lab bioRxiv 2026
www.biorxiv.org/content/10.6...

Injury-induced electrochemical coupling triggers organ growth Organ repair and growth rely on coupling tissue-wide membrane depolarization with intracellular proliferative signaling.

New paper alert!🤩Super proud that our story led by superstar postdocs @liujinghui.bsky.social and @nerlielisa.bsky.social is finally out! We found how electrical signals are key for promoting organ regenerative growth!!! A thread 🧵https://www.science.org/doi/10.1126/sciadv.aec0687

If you are interested in a PhD on protein science in a very pretty part of Southern Germany, consider this amazing opportunity to work with @hadeerelhabashy.bsky.social.

Can we tune a plant’s epigenetic toolkit to disrupt plant homeostasis in ways that enable phenotypic innovation?

🌱Check out our new Opinion Paper with @thanvisrikant.bsky.social discussing this topic in @cp-trendsplantsci.bsky.social!

www.sciencedirect.com/science/arti...

Congratulations!

We have a new preprint on bioRxiv from postdoc Delai Huang and colleagues. It's not about peacocks. www.biorxiv.org/content/10.6...

Development's Pathway to Independence Programme Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...

Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:

Mentoring
Profile raising
Leadership training
Network building

Spread the word...

www.biologists.com/grants/devel...

Exciting new #Zebrafish research from the #WeinsteinLab, led by Jong Park!
“Specialized gas-exchange endothelium of the zebrafish gill” —

www.biorxiv.org/content/10.6...

Amazing to see red blood cells moving through the gills! Don’t forget to check out the supplemental movies ;-)

***Super cool-project alert***⚠️ Come work with @dirkmetzler.bsky.social and me in trying to understand how transcriptional noise evolves in a phylogenetic context 🧬 Deadline 15th Dec 2025 (Project funded by @dfg.de @gevol.bsky.social)

Come join us in Heidelberg for the first German fish meeting 👩‍🔬👨‍🔬🧬🔬🐟🐠

How does messenger RNA (mRNA) get out of the nucleus to become a protein? Eukaryotic mRNA is packaged, exported, and then translated in the cytoplasm. But how do these steps work? And what are open questions? Check out our new review for our take: www.annualreviews.org/content/jour... (1/3)

Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv:
www.biorxiv.org/content/10.1...

Insertion of an invading retrovirus regulates a novel color trait in swordtail fish For over a century, evolutionary biologists have been motivated to understand the mechanisms through which organisms adapt to their environments. Coloration and pigmentation are remarkably variable wi...

I am so excited to share new work on a TE insertion that regulates iridescence in swordtails, led by fantastic grad student @nadiahaghani.bsky.social and with help from many coauthors! In a time that has been so difficult to navigate, this & other projects have kept my spirits up: shorturl.at/NE65A

🔍 In our review, led by Tina Munch, a hydrocephalus neurosurgeon, we explore this question. We examined the role of cilia in human hydrocephalus and highlight a key insight: primary cilia may play a more critical role than motile cilia, particularly through their influence on brain development.

Dual transcriptional activities of PAX3 and PAX7 spatially encode spinal cell fates through distinct gene networks How do transcription factors, with pleotropic functions, generate organized cellular diversity in developing tissues? This study shows that PAX3 and PAX7 orchestrate spinal cord patterning by acting a...

Good to see this study from Ribes & co in print: PAX3/PAX7 transcription factors control neural tube patterning by simultaneously repressing ventral fates via H3K27me3 deposition at silencers & activating dorsal fates as pioneer factors at enhancers
@ribes
journals.plos.org/plosbiology/...

1/2 Want to become up to date with pangenomes and genome graphs and their history? Check out this fantastic review by @zbao.bsky.social!

Complexity welcome: Pangenome graphs for comprehensive population genomics
#pangenomes #plantscience #genomegraphs
www.cambridge.org/core/journal...

The Question: We know the spinal cord has 11 molecularly distinct progenitor domains generating distinct neurons, but how are these linked by actual LINEAGE relationships? When do progenitors commit to specific cardinal neuron fates, and how early is that commitment resolved?

Thank you Leo. The labour of many people!

Cell-cell communication as underlying principle governing color pattern formation in fishes The diverse pigmentation patterns of animals are crucial for predation avoidance and behavioral display, yet mechanisms underlying this diversity remain poorly understood. In zebrafish, Turing models ...

Thank you to all involved labs, especially @dparichy.bsky.social for decades of passion for these species. Worth a read: cell-cell communication as underlying principle governing color pattern formation in fishes www.biorxiv.org/content/10.1... @zebrafishrock.bsky.social @mpi-bio-fml.bsky.social

Happy to have contributed to this big story. We present new genome assemblies, genus-wide complementation and allele-specific expression analyses in hybrids between zebrafish and closely related Danio species with divergent pigment patterns. A vertebrate model genus for basic comparative biology.