Interorgan crosstalk typically occurs via the bloodstream. We showed that brain-heart-gut interplay also occurs in their electrophysiology at infra-slow timescales. We found that fluctuations in the gut are typically followed by the brain and heart after tens of seconds.
doi.org/10.64898/202...

Very excited to share new findings from an NIMH-funded R21 on the neurodevelopment of worry! Manuscript led by super 🌟 Postdoctoral Scholar in the lab @ceciwestbrook.bsky.social , check it out! 👇👇👇 @psychiatry.pitt.edu

On Tues, 4/28, 10am, Host Dr. @brainbodylab.bsky.social & the #BrainBodyResearchInstitute are EXCITED to welcome UCLA's Dr. @skhalsa.bsky.social 👉 "Interoceptive Neuroscience as a Catalyst for the Next Era of Translational Neurobiology" Register Here ➡️ mountsinai.zoom.us/webinar/regi...

GastroPy is now out in early beta! Please to share our Python toolbox for electrogastrography and stomach-brain coupling analyses. It includes tools for cleaning, visualising, and analysing EGG data, plus fMRI stomach-brain coupling workflows. Docs, code, and preprint below. osf.io/preprints/ps...

Circadian-independent light regulation of mammalian metabolism - Nature Metabolism Rao and Xue discuss emerging evidence in mice and humans of circadian-independent regulation of metabolic responses by light.

#Throwback 🧪

PERSPECTIVE | Circadian-independent light regulation of mammalian metabolism

F Rao & T Xue

Wow

I am pleased to announce the Embodied Minds Summit, a two-day gathering on interoception, consciousness, and the future of self-understanding in the age of artificial intelligence. May 2–3, 2026 | Los Angeles
embodiedminds.ai

Mesocorticolimbic connectivity and motivational sensitivity: sex-specific effects of puberty in early adolescence Neuropsychopharmacology - Mesocorticolimbic connectivity and motivational sensitivity: sex-specific effects of puberty in early adolescence

How does puberty shape how brain connectivity relates to environmental stimuli? And might this inform sex differences in psychiatric risk during this period? Excited to share new work now out in @npp-journal.bsky.social @acnporg.bsky.social examining this! rdcu.be/e9ASG tinyurl.com/56dhse2t. A 🧵1/n

Low-intensity focused ultrasound to human amygdala reveals a causal role in ambiguous emotion processing and alters local and network activity The amygdala shows abnormal metabolism in depression, a disorder marked by altered emotion, motivation, and learning. Yet its causal role in these pro…

Very happy our first paper using ultrasound stimulation (TUS) to stimulate the human amygdala (BLA) got out in @cp-neuron.bsky.social today! 🎉🥳🔊Great FUN with co-first authors @mirunmigyu.bsky.social @lilweb.bsky.social in @mkflugge.bsky.social 's lab!
www.sciencedirect.com/science/arti...

🚨FREE WEBINAR ANNOUNCEMENT🚨

Get an early start to #statnerdsummer with a free seminar on how multilevel models and structural equation models intersect.

I'll be showing this through MLM and SEM growth curves.

Sign up for free! Share widely!

You can register here: smart-workshops.com/workshops

Graphical abstract showing four panels. Panel 1: a person in an MRI scanner with blue cognitive thought bubbles drifting from their head and pink body thought bubbles from their torso, with organs glowing inside. Panel 2: blue bubbles for cognitive items (Self, Words, Focus, Images, Future, Past) are larger than pink bubbles for body items (Breathing, Movement, Stomach, Heart, Skin, Bladder), with arrows showing body thoughts link to more negative and less positive emotion. Panel 3: physiological traces (EGG, ECG, respiratory) show higher arousal with body-wandering; a bar chart shows cognitive items (Past, Future, Repetitive, Vivid) correlate with more ADHD and depression symptoms while body items (Breath, Stomach, Skin, Heart) correlate with fewer. Panel 4: medial brain with thalamus, somatomotor cortex, and interoceptive regions highlighted, plus a chord diagram showing connectivity between these three regions.

New paper in PNAS! When the mind wanders, it often drifts to the body. We call this "body-wandering". These thoughts are often negative, but are associated with reduced ADHD & depression symptoms, driven by a distinct interoceptive-allostatic brain signature. pnas.org/doi/10.1073/pnas.2520822123

🎉 Excited to share our publication in PNAS! 🎉
What happens when our stream of consciousness turns towards the body? Our fMRI study of 536 individuals finds that 'body-wandering' is associated with patterns of brain connectivity, physiology, affect, and mental health:
www.pnas.org/doi/full/10....

📣 The 2026 SMaRT Workshops schedule is officially LIVE — with workshops covering SEM, MLM, dyadic methods, time series, machine learning, clinical trials design, and more.

STATS NERD SUMMER is HERE.

Come learn something. 🧑‍🎓

smart-workshops.com/workshops

Please share and RP🙏

More info 👇

1/n

Flyer with details of the upcoming speaker series event.

Save the date for the next Child Study Center Speaker Series event with psychology Professor Vanessa LoBue!

Graphical abstract showing three panels. Left panel, "Multiorgan Interoception Measures," depicts a translucent human body silhouette with anatomically rendered heart (red) and lungs (blue), accompanied by schematic icons for three psychophysical tasks: the Respiratory Resistance Sensitivity Task (RRST), Heart Rate Discrimination Task (HRDT), and an auditory control condition. N = 241 participants. Center panel, "Psychophysical Modelling and Individual Differences," shows a fan of overlapping sigmoid psychometric curves in blue-to-red gradient representing individual variation in perceptual threshold (α) and precision (β), a hierarchical Bayesian model diagram, and icons for metacognitive bias and M-Ratio efficiency. Right panel, "Key Finding: No Cross-Modal Relationship," displays a scatterplot of cardiac versus respiratory sensitivity with a flat regression line (r ≈ 0, BF₀₁ > 6), a compact Bayes Factor heatmap with mostly blue null-supporting cells and one orange cell indicating that subjective confidence is shared across modalities (r = 0.51***). Takeaway: interoceptive ability is modality-specific.

Is there a single "interoceptive sense"? Our new study in
@commspsychol.nature.com says: probably not. In 241 participants, cardiac and respiratory interoception were completely uncorrelated — only subjective confidence was shared across domains. www.nature.com/articles/s44... #psychscisky 🧪

Congrats, Leah! Always fascinated by your work🫀😍

So happy to see our work on organ-specific interoception is out! 🫀🫁
Here is the thread detailing the results when preprinted 🧵:
bsky.app/profile/leah...

Mental Disorders as Homeostatic Property Clusters This narrative review explores the idea of understanding mental disorders according to homeostatic property clusters rather than through typical classification systems.

Hey friends, my new paper was just published in JAMA Psychiatry. I draw on biological species classification to sketch a new framework for psychiatric nosology.

Brief summary follows below.

Full text link: jamanetwork.com/journals/jam...

🧪 #PsychSciSky #MentalHealth

Unexplained pain and affectionate touch — two self-report questions that outperform a 42-item interoception battery in predicting mental health osf.io/preprints/ps...

Translocation of bacteria from the gut to the brain in mice Recent studies link gut dysbiosis to neurological disease, but the underlying mechanisms remain unclear. This study shows that a high-fat diet increases gut permeability and enables bacterial transloc...

Bacteria in our BRAINS??!

We observed translocation of bacteria from the gut to the brain via the vagus nerve.

This occurred after high fat diet, or without dietary changes in mouse models of Alzheimer’s, Parkinson’s, and autism.

journals.plos.org/plosbiology/...

The thirsty brain: Integrating molecular signals, neural circuit and behavior Drinking behavior, for most organisms, is essential for maintaining fluid homeostasis and fundamental to survival and normal physiological functions. Physiologically motivated drinking is typically…

This review systematically discusses the neural and hormonal mechanisms that regulate thirst generation and drinking behavior by integrating molecular pathways and peripheral-central nervous system communication, while highlighting key research gaps for future clinical translation.

So much gratitude to you and @eriknook.bsky.social! Absolutely loved the preconference🖤

A 3D cartoon alien with a round pink face looks forward. It has large green eyes, a small pink nose, bright blue lips, and short orange eyebrow shapes above its eyes. Blue ear-like shapes stick out on both sides of its head. Two thin antennae rise from the top of its head and bend outward, each ending in shiny, speckled spheres. The background is plain light gray.

How do humans learn to weight signals when reasoning about emotions? Children change both kinds of cues they rely on and the ways they use cues in their reasoning. New work from Andrea Stein using adorable stimuli, too. 🧪 dx.doi.org/10.1111/desc... #cogsci #devsci #AffectSci
#PsychSciSky

Intestinal interoceptive dysfunction drives age-associated cognitive decline - Nature Age-related microbiome changes increase medium-chain fatty acid-producing bacteria, driving GPR84-mediated myeloid inflammation, impaired vagal signalling and hippocampal dysfunction; targeting this g...

Intestinal interoceptive dysfunction drives age-associated cognitive decline www.nature.com/articles/s41...

See you tomorrow at @affectscience.bsky.social #SAS2026!

'A dual-function framework of interoception: the information and coordination modes of interoceptive signaling'

by Catherine Tallon-Baudry, Marie Loescher (@marieloescher.bsky.social) & Anthony Clément

www.cell.com/trends/neuro...

Every time you experience something new, your brain faces a decision: Should it update an existing memory or create a new one?

In our new paper in @sfnjournals.bsky.social #JNeurosci, we isolate that exact decision, moment-by-moment during learning 🧵

Thrilled that this first empirical paper out of the lab is posted, led by Sandarsh Pandey, asking:

Depression (and other internalizing disorders) involve profound changes to sense of self. How can we study these differences using rigorous decision-making methods?

(alt link: tinyurl.com/2kk59dje)

2. I will also present a poster (with @jennenge.bsky.social and Derek Spangler), titled "Associations between child maltreatment and somatic amplification are moderated by emodiversity," in Poster Session 1.

I look forward to seeing everyone at #SAS2026!