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6 Common Medications That May Lower Your Dementia Risk

People who receive the shingles vaccine may have a lower risk of developing dementia, with some studies estimating a 15-20% reduction.

Includes research by @pascalge.bsky.social supported by a Knight Initiative for Brain Resilience Pilot Grant.

Read more: www.nytimes.com/2026/04/17/w...

44 minutes ago 2 1 0 0
Michael Greicius, Stanford Neurologist, Knight Initiative for Brain Resilience Steering Committee member, and founding director of the Stanford Memory Disorders Center.

Michael Greicius, Stanford Neurologist, Knight Initiative for Brain Resilience Steering Committee member, and founding director of the Stanford Memory Disorders Center.

Victor Henderson, Stanford Neurologist

Victor Henderson, Stanford Neurologist

Stanford neurologists Michael Greicius and Victor Henderson explain what science knows about why women develop Alzheimer’s disease at higher rates than men—and the many things science doesn’t yet know.

Learn more: med.stanford.edu/news/insight...

4 days ago 3 1 0 0
Kathleen Poston is a neurologist and division chief for movement disorders at Stanford Medicine. She's also a member of the steering committee for the Knight Initiative for Brain Resilience at Wu Tsai Neuro.

Kathleen Poston is a neurologist and division chief for movement disorders at Stanford Medicine. She's also a member of the steering committee for the Knight Initiative for Brain Resilience at Wu Tsai Neuro.

Todd Coleman, Kathleen Poston, and Linda Nguyen speak at the 2025 Wu Tsai Neurosciences Institute Symposium.

Todd Coleman, Kathleen Poston, and Linda Nguyen speak at the 2025 Wu Tsai Neurosciences Institute Symposium.

Symptoms like constipation, sleep disturbances, and loss of smell can appear years before Parkinson's diagnosis. In today's podcast, Kathleen Poston discusses ongoing research exploring where Parkinson's begins and how to slow its progression.

Listen now: neuroscience.stanford.edu/news/could-p...

5 days ago 3 1 0 1
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From humble beginnings to unlocking lysosomal secrets Monther Abu–Remaileh will receive the ASBMB’s 2026 Walter A. Shaw Young Investigator Award in Lipid Research at the ASBMB Annual Meeting, March 7-10 in Washington, D.C.

Congratulations to Institute Scholar @abu-remaileh.bsky.social on receiving the ASBMB Walter A. Shaw Young Investigator Award in Lipid Research!
His journey from East Jerusalem to Stanford highlights resilience and passion for science and mentorship:

1 week ago 9 3 1 0
Wu Tsai Neuro Faculty Affiliate Kalanit Grill-Spector participates in a brainstorming session with other Institute affiliates at the 2024 Wu Tsai Neurosciences Institute Scientific Retreat.

Wu Tsai Neuro Faculty Affiliate Kalanit Grill-Spector participates in a brainstorming session with other Institute affiliates at the 2024 Wu Tsai Neurosciences Institute Scientific Retreat.

Postdoc Scholar Pilleriin Sikka shares a scientific talk titled "Anesthesia-Induced Dreaming: Frequency, Safety, and Therapeutic Outcomes" at the 2024 Wu Tsai Neurosciences Institute Retreat.

Postdoc Scholar Pilleriin Sikka shares a scientific talk titled "Anesthesia-Induced Dreaming: Frequency, Safety, and Therapeutic Outcomes" at the 2024 Wu Tsai Neurosciences Institute Retreat.

Wu Tsai Neuro faculty affiliates and members of their labs share their scientific discoveries and spark new collaborations at the 2024 Institute Retreat poster session.

Wu Tsai Neuro faculty affiliates and members of their labs share their scientific discoveries and spark new collaborations at the 2024 Institute Retreat poster session.

2024 Wu Tsai Neurosciences Institute Retreat attendees gather for a group photo.

2024 Wu Tsai Neurosciences Institute Retreat attendees gather for a group photo.

We invite Wu Tsai Neuro faculty affiliates and members of their labs to join us on Monday, May 18, at our 2026 Institute Retreat.

⚠️ Attendance is limited. Registration required.

🧠 Learn more: neuroscience.stanford.edu/events/2026-...

🎟️ Register here by April 21: wutsaineuro-retreat-26.zite.so

1 week ago 3 1 0 1
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Life Science Research Professional 1 in School of Medicine, Stanford, California, United States Stanford University is seeking a Life Science Research Professional 1 to study the mechanisms of aging and rejuvenation, particularly in a variety of....

Interested in aging and rejuvenation?

We have a new Research Assistant position to understand aging at the cellular level!!

Come join our team!!! 😎

careersearch.stanford.edu/jobs/life-sc...

1 week ago 23 14 1 0
Rahul Nagvekar, a Genetics PhD candidate at Stanford University in the Brunet Lab, presents his research in a talk titled, "Engulfment by brain myeloid cells of a short-lived vertebrate."

Rahul Nagvekar, a Genetics PhD candidate at Stanford University in the Brunet Lab, presents his research in a talk titled, "Engulfment by brain myeloid cells of a short-lived vertebrate."

Jordan Moore, a Postdoc at Stanford University in the Buckwalter Lab, shared his research in a talk titled, Injectable Drug-Eluting Scaffold To Improve Cognition after Ischemic Stroke."

Jordan Moore, a Postdoc at Stanford University in the Buckwalter Lab, shared his research in a talk titled, Injectable Drug-Eluting Scaffold To Improve Cognition after Ischemic Stroke."

Jordan Moore, a Postdoc at Stanford University in the Buckwalter Lab, shared his research in a talk titled, Injectable Drug-Eluting Scaffold To Improve Cognition after Ischemic Stroke."

Jordan Moore, a Postdoc at Stanford University in the Buckwalter Lab, shared his research in a talk titled, Injectable Drug-Eluting Scaffold To Improve Cognition after Ischemic Stroke."

Rahul Nagvekar, a Genetics PhD candidate at Stanford University in the Brunet Lab, presents his research in a talk titled, "Engulfment by brain myeloid cells of a short-lived vertebrate."

Rahul Nagvekar, a Genetics PhD candidate at Stanford University in the Brunet Lab, presents his research in a talk titled, "Engulfment by brain myeloid cells of a short-lived vertebrate."

Yesterday, Jordan Moore, a postdoc in the Buckwalter Lab, discussed his research, "Injectable Drug-Eluting Scaffold To Improve Cognition after Ischemic Stroke." Rahul Nagvekar @brunetlab.bsky.social shared his research in a talk, "Engulfment by brain myeloid cells of a short-lived vertebrate."

1 week ago 3 1 0 0
Monther Abu-Remaileh | Intra-lysosomal lipid metabolism and neurodegeneration
Monther Abu-Remaileh | Intra-lysosomal lipid metabolism and neurodegeneration YouTube video by American Society for Biochemistry and Molecular Biology (ASBMB)

Monther Abu–Remaileh (@stanford-chemh.bsky.social) is advancing lysosomal lipid #biochemistry — earning the 2026 ASBMB Walter A. Shaw Young Investigator Award. His lab focuses on how lysosomal dysfunction contributes to neurodegenerative disease.

⏯️Watch his #ASBMB26 talk: youtu.be/BugAr1mMyJ4?...

2 weeks ago 5 3 0 0
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An array of fifteen portraits on a green and purple striped background.

An array of fifteen portraits on a green and purple striped background.

From rejuvenating brain plasticity with magnetic stimulation to tracking genome changes with age, Stanford researchers are exploring new paths to brain aging and resilience.

The Knight Initiative is supporting 4 of 8 new seed grant projects. Read more: brainresilience.stanford.edu/news/new-ide...

2 weeks ago 2 1 0 0
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Pythons’ feast-and-famine life hints at new weight-loss pathway Pythons eat huge meals after monthslong fasts. Researchers identified molecules that skyrocket in their blood after a meal. One caused obese mice to eat less and lose weight, similar to semaglutide.

Institute Scholar Jon Long & team studied the extreme metabolism of pythons—snakes that gorge themselves and then go months without eating—leading to discovery of an appetite-reducing molecule that could be a starting point for new weight-loss drugs:

3 weeks ago 2 1 0 0
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Winter 2026: Predicting lifespan, lysosome atlas, Alzheimer’s beginnings Recent advances in the science of healthy brain aging from the Knight Initiative for Brain Resilience at Stanford University. Watching a lifetime in motion hints at the architecture of aging By midlif...

A clearer picture of brain aging is emerging.

Explore recent research supported by the Knight Initiative on early signals of lifespan, cellular recycling in the brain, and mechanisms underlying neurodegeneration in our Winter 2026 review.

www.linkedin.com/pulse/winter...

3 weeks ago 2 1 0 0
Bruker's manufacturer representative, Saaussan Madi, shared datasets on marmoset brains, which exemplified how isotropic resolution allows precise determination of fiber tracks. Image courtesy of J. Hata and H. Okano of Keio University, CIEA, Kanagawa, Japan.

Bruker's manufacturer representative, Saaussan Madi, shared datasets on marmoset brains, which exemplified how isotropic resolution allows precise determination of fiber tracks. Image courtesy of J. Hata and H. Okano of Keio University, CIEA, Kanagawa, Japan.

Apply for Neuroimaging Pilot Grants and explore the possibilities of MRI in neuroscience research!

The Neurosciences Preclinical Imaging Lab invites Stanford researchers of all career stages to apply. Awards up to $6,000.

Learn more and apply by April 10: neuroscience.stanford.edu/shared-resou...

4 weeks ago 4 3 0 0
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Announcing the 2026 Neurosciences Postdoctoral Scholars How do we advance our understanding of the mind and brain in aging, disease, and daily experience? How

Congrats to our 2026 Neurosciences Postdoc Scholars!

They bring expertise in biology, chemistry, engineering, genetics, physiology, neuroscience, psychiatry, and radiology to research projects spanning different scales of neuroscience.

Learn more: neuroscience.stanford.edu/news/announc...

4 weeks ago 2 1 0 0
Pythons produce a hunger-suppressing molecule called pTOS after meals. The same molecule tells human and mouse brains it's time to stop eating. 

Image description: Yellow python with a black background. 

Image credit: Denis Doukhan/Pixabay.

Pythons produce a hunger-suppressing molecule called pTOS after meals. The same molecule tells human and mouse brains it's time to stop eating. Image description: Yellow python with a black background. Image credit: Denis Doukhan/Pixabay.

New study on Pythons—snakes that can go a year without eating—hints at a potential weight-loss drug with fewer side effects than GLP-1 drugs. Research led by the Long Lab at Stanford and supported in part by the Knight Initiative.

Learn more: brainresilience.stanford.edu/news/study-p...

1 month ago 2 1 0 0
Christoph Thaiss is a Wu Tsai Neurosciences Institute affiliate, an assistant professor of pathology at Stanford Medicine, and a core investigator at the Arc Institute in Palo Alto.

Christoph Thaiss is a Wu Tsai Neurosciences Institute affiliate, an assistant professor of pathology at Stanford Medicine, and a core investigator at the Arc Institute in Palo Alto.

Could boosting gut–brain communication prevent memory loss?

New research by @christophthaiss.bsky.social suggests restoring vagus nerve activity can reverse cognitive decline in aging mice. He joins us to discuss microbes, memory, and internal senses.

neuroscience.stanford.edu/news/could-b...

1 month ago 3 2 0 1
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Dr. Kaestner works with a research subject in the Koret Human Neurosciences Lab at Wu Tsai Neuro.

Dr. Kaestner works with a research subject in the Koret Human Neurosciences Lab at Wu Tsai Neuro.

Interested in leveraging EEG and/or TMS in your research? The Koret Human Neurosciences Lab at Wu Tsai Neuro invites Stanford researchers to apply for Human Neuro Pilot grants, awarding up to $10,000 per grant.

Learn more and apply by April 10: neuroscience.stanford.edu/shared-resou...

1 month ago 4 1 0 0
Annie Goettemoeller, a Wu Tsai Neurosciences Institute Postdoctoral Scholar supported by the Knight Initiative for Brain Resilience, in her lab.

Annie Goettemoeller, a Wu Tsai Neurosciences Institute Postdoctoral Scholar supported by the Knight Initiative for Brain Resilience, in her lab.

Annie Goettemoeller looks through a microscope in her lab. Photo by Andrew Brodhead.

Annie Goettemoeller looks through a microscope in her lab. Photo by Andrew Brodhead.

Ongoing research explores how epilepsy-like activity may influence the spread of Alzheimer’s pathology in the brain. This work is led by Brain Resilience Postdoc Scholar Annie Goettemoeller in the Soltesz Lab @stanfordmedicine.bsky.social.

Learn more: brainresilience.stanford.edu/news/qa-prob...

1 month ago 2 1 0 0
Meena Chakraborty, PhD Candidate, Stanford University, presents her research at the March 2026 Brain Resilience Seminar.

Meena Chakraborty, PhD Candidate, Stanford University, presents her research at the March 2026 Brain Resilience Seminar.

Bianca Palushaj presents her research at the March 2026 Brain Resilience Seminar.

Bianca Palushaj presents her research at the March 2026 Brain Resilience Seminar.

Imani Porter presents her research at the March 2026 Brain Resilience Seminar.

Imani Porter presents her research at the March 2026 Brain Resilience Seminar.

Julian Garcia, Brain Resilience Postdoc, shared his research in a talk titled "The light side of the force."

Julian Garcia, Brain Resilience Postdoc, shared his research in a talk titled "The light side of the force."

In our monthly seminar, Julian Garcia of the Wendy Liu Lab presented his research in a talk titled "The Light Side of the Force." Meena Chakraborty of the Bhatt Lab discussed her research, "The gut-immune-brain connection in Parkinson's Disease," with lab mates Bianca Palushaj and Imani Porter.

1 month ago 3 1 0 0
Katrin J Svensson, Associate Professor of Pathology

Katrin J Svensson, Associate Professor of Pathology

Nirao Shah, Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator), of Neurobiology and, by courtesy, of Obstetrics and Gynecology

Nirao Shah, Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator), of Neurobiology and, by courtesy, of Obstetrics and Gynecology

Longzhi Tan, Assistant Professor of Neurobiology

Longzhi Tan, Assistant Professor of Neurobiology

How does pregnancy reshape the mother's brain at a molecular level?

In today’s podcast, Nirao Shah and Katrin Svensson discuss the new Stanford Neuro-Pregnancy Initiative with Longzhi Tan and what neuroscience can tell us about pregnancy.

neuroscience.stanford.edu/news/new-neu...

1 month ago 3 1 0 1
Laura Gwilliams (left), Jill Kries (second from left) and other members of the Gwilliams lab discuss the neuroscience of language. In the lab's latest paper, Kries, Gwilliams, and  KU Leuven's Maaike Vandermosten investigated the underlying mechanisms of post-stroke aphasia. Image by Jess Alvarenga.

Laura Gwilliams (left), Jill Kries (second from left) and other members of the Gwilliams lab discuss the neuroscience of language. In the lab's latest paper, Kries, Gwilliams, and KU Leuven's Maaike Vandermosten investigated the underlying mechanisms of post-stroke aphasia. Image by Jess Alvarenga.

In stroke patients with aphasia, the brain spends too little time processing ambiguous sounds, suggesting new targets for precision therapies. (@lauragwilliams.bsky.social, @kriesjill.bsky.social)

Read the story by @stellamayerhoff.bsky.social here: neuroscience.stanford.edu/news/why-bra...

1 month ago 12 3 0 1
Courtesy of Ian Guldner, Stanford University

Courtesy of Ian Guldner, Stanford University

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

Read the full story by @thetransmitter.bsky.social here: www.thetransmitter.org/aging/aging-...

1 month ago 3 1 0 0

Silencing during iPSC differentiation is a major but underrecognized challenge and hard to fund. We are deeply grateful to @chanzuckerberg.bsky.social for supporting this project.
Also, thanks to @brainresilience.bsky.social and @hdfcures.bsky.social for supporting my postdoctoral fellow!

2 months ago 1 1 0 0
Please wait whilst we redirect you All content on this site: Copyright © 2026 Elsevier B.V., its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.

Losing sleep over #iPSC transgene silencing after differentiation?
Same here.

Bright in iPSCs.
Gone after differentiation.

Our paper in @cp-cellstemcell.bsky.social maps what actually keeps expression on👇
www.cell.com/cell-stem-ce...
🔗 Free access (50 days):
www.sciencedirect.com/science/auth...

2 months ago 12 11 1 0
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Aging slows breakdown of synaptic proteins, raising disease risk Recent research unveils new links between the brain’s waste management systems and neurodegeneration.

Ian Guldne, @carolynbertozzi.bskyverified.social, @abu-remaileh.bsky.social & team are exploring relationship between synapse loss & defective protein recycling in the aging brain, offering new insights into brain health & disease risk news.stanford.edu/stories/2026... @brainresilience.bsky.social

2 months ago 3 2 0 0
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Vinod Menon, Rachel L. and Walter F. Nichols, MD., Professor of Psychiatry & Behavioral Science at Stanford Medicine, Wu Tsai Neurosciences Institute affiliate.

Vinod Menon, Rachel L. and Walter F. Nichols, MD., Professor of Psychiatry & Behavioral Science at Stanford Medicine, Wu Tsai Neurosciences Institute affiliate.

From Our Neurons to Yours, Wu Tsai Neurosciences Institute, Stanford University.

From Our Neurons to Yours, Wu Tsai Neurosciences Institute, Stanford University.

Why do our minds wander?

Our podcast is back! Today, we speak with cognitive scientist Vinod Menon about the brain's default mode network behind daydreaming, rumination, and our sense of self—and its links to ADHD, depression, and Alzheimer’s disease.

neuroscience.stanford.edu/news/why-do-...

2 months ago 4 1 0 0
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Aging brains pile up damaged proteins Proteins that start life inside neurons build up faster in old age and spread to other brain cells—a

Proteins that start inside neurons accumulate faster with age and increasingly appear in microglia, the immune cells that prune damaged synapses, according to new research supported by the Knight Initiative. Led by Ian Guldner in the Wyss-Coray Lab.

brainresilience.stanford.edu/news/aging-b...

2 months ago 2 1 0 0
Kit Vodehnal, a neurosciences PhD candidate in the lab of Marius Wernig, presented their research in a talk titled "Neuron-glia interactions in regulating protein aggregation in human cell models."

Kit Vodehnal, a neurosciences PhD candidate in the lab of Marius Wernig, presented their research in a talk titled "Neuron-glia interactions in regulating protein aggregation in human cell models."

Birgitt Schuele, an associate professor at Stanford Medicine: Department of Pathology, discussed emerging research about "Neurodegeneration across Borders: Resilience, Fieldwork, and Gene Therapy."

Birgitt Schuele, an associate professor at Stanford Medicine: Department of Pathology, discussed emerging research about "Neurodegeneration across Borders: Resilience, Fieldwork, and Gene Therapy."

In yesterday's monthly seminar, Kit Vodehnal of the Wernig Lab discussed "Neuron-glia interactions in regulating protein aggregation in human cell models," and Birgitt Schuele, an associate professor of pathology, shared "Neurodegeneration across Borders: Resilience, Fieldwork, and Gene Therapy."

2 months ago 4 1 0 0
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The Spatio-Temporal Dynamics of Phoneme Encoding in Aging and Aphasia During successful language comprehension, speech sounds (phonemes) are encoded within a series of neural patterns that evolve over time. Here we tested whether these neural dynamics of speech encoding...

A new study by @lauragwilliams.bsky.social, @kriesjill.bsky.social, and team suggests that phonetic features are robustly encoded in healthy older adults, but show reduced encoding strength in individuals with post-stroke aphasia during speech comprehension.

www.jneurosci.org/content/46/4...

2 months ago 7 3 0 1
Text: Knight Initiative for Brain Resilience Winter 2026 Symposium. 

Image collage, top row, from left: 1. Dr. Brit Mollenhauer, University Medical Center Göttingen. 2. Dr. James Olzmann, University of California at Berkeley. 3. Dr. Michael Ward, National Institutes of Health.

Bottom row, from left: 1. Dr. Gaurav Chattree, Stanford University. 2. Dr. Daisy Ding, Stanford University. 3. Dr. Frank Longo, Stanford University.

Text: Knight Initiative for Brain Resilience Winter 2026 Symposium. Image collage, top row, from left: 1. Dr. Brit Mollenhauer, University Medical Center Göttingen. 2. Dr. James Olzmann, University of California at Berkeley. 3. Dr. Michael Ward, National Institutes of Health. Bottom row, from left: 1. Dr. Gaurav Chattree, Stanford University. 2. Dr. Daisy Ding, Stanford University. 3. Dr. Frank Longo, Stanford University.

Our symposium is today!

We look forward to scientific talks by Brit Mollenhauer of UMG, James Olzmann of @ucberkeleyofficial.bsky.social, Michael Ward of NIH, Gaurav Chattree of @stanfordhealthcare.bsky.social, Daisy Ding of @stanfordneuro.bsky.social, and Frank Longo @stanfordmedicine.bsky.social.

2 months ago 2 1 0 0
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A new atlas could help guide researchers studying neurological disease The database of lysosomal proteins is already helping researchers study how brain cells’ waste and

A new atlas maps lysosomal proteins across brain cell types, helping researchers study how breakdowns in cellular waste and recycling systems contribute to Alzheimer’s and Parkinson’s disease. Supported by a Knight Initiative Catalyst Momentum Award.

brainresilience.stanford.edu/news/new-atl...

2 months ago 2 1 0 0