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Posts by Timme-Laragy Lab

Want to know how much the Bluesky #zebrafish community has grown? We now follow half as many shoal members compared to the peak of Twitter (2.2k).

If you work with cool teleost models in biomedical, developmental or evolutionary research, we want to follow you! Reach out if this describes you 🙏 🧪

2 months ago 23 7 1 0
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UMass Amherst Researchers Help Uncover Hidden Genetic Drivers of Diabetes | UMass Amherst A new study from epidemiologists Cassandra Spracklen and Chi “Josh” Zhao shows key Type 2 diabetes genes act outside blood, highlighting the roles of the pancreas, liver and muscle.

New research co-led by Prof. Cassandra Spracklen UMass Amherst School of Public Health and Health Sciences reveals hundreds of hidden genetic drivers that directly influence Type 2 diabetes—clear targets for future therapies. @helmholtzmunich.bsky.social
https://bit.ly/4tcKov4

2 months ago 1 1 0 0

Yeah, turns out they don’t have a placenta…🙄

8 months ago 1 0 1 0
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These are the most challenging times for early-career scientists and engineers.

My team is doing its bit to help by maintaining and even expanding our database of funding opportunities for early-career researchers.

We found 437 of them.

Download it freely here: research.jhu.edu/rdt/funding-...

8 months ago 315 201 6 3

Big misalignment between #MAHA
(Make America Healthy Again) statements and slashed funding of research, which can damage this important field for a long time (pollution research) 🔽

10 months ago 16 6 1 0
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Trump Has Cut Science Funding to Its Lowest Level in Decades (Gift Article) The lag in funding extends far beyond D.E.I. initiatives, affecting almost every area of science: chemistry, computing, engineering, materials and more.

NSF Physics was cut by 85%, basically wiping out most of its capacity for supporting research.

NSF Astronomy was cut by 53%

Undergrad education was cut by 71% and research on learning by 79%

Graduate education was cut by 100% to ZERO.

#GiftLink ⚛️🔭

www.nytimes.com/interactive/...

11 months ago 1164 804 38 90
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Trump’s NIH And NSF Cuts Estimated To Cost The U.S. Economy $10 Billion Annually Economists find public R&D drives a quarter of U.S. productivity growth — and pays for itself

Trump’s proposed $23 billion in cuts to NIH & NSF could cost the U.S. economy at least $10 billion a year, according to new research. Public science funding drives innovation, productivity, and long-term growth. Slashing it isn’t saving money; it’s losing our future. www.forbes.com/sites/johndr...

11 months ago 19 16 0 2
Image of the logo for the Zebrafish Disease Models Conference (ZDM18). Text that reads 'ZDM18 Boston, MA, USA 2025' and two silhouettes of zebrafish that are black and red.

Image of the logo for the Zebrafish Disease Models Conference (ZDM18). Text that reads 'ZDM18 Boston, MA, USA 2025' and two silhouettes of zebrafish that are black and red.

Attention ZDMS Members and greater fish community:

A message from the Local Organizing Committee for #ZDM18!

The Zebrafish Disease Models Society is excited to host ZDM18 in Boston in October! Read this thread for more about the conference and its upcoming deadlines. (1/8)

11 months ago 7 6 2 0
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a cartoon says hey everybody an old man 's talking while bart simpson looks on ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on

Bluetorial: My NIH grant got funded; The money is in the bank

What happens behind the scenes with NIH fund transfers

1 year ago 323 97 3 20
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As we learn Gene Hackman had severe Alzheimer’s, we find out that Trump and Musk are killing research into Alzheimer’s cures.

The Trump/Musk crime spree has to be stopped. Get their hands off our government.

1 year ago 364 129 10 2
Phylogenetic tree showing relationships between zebrafish, mice and cartilaginous fishes. It shows the 3R genome duplication event in teleost lineage. Credit to MacDonald et al. 2018.

Phylogenetic tree showing relationships between zebrafish, mice and cartilaginous fishes. It shows the 3R genome duplication event in teleost lineage. Credit to MacDonald et al. 2018.

Did you know the last common ancestor of #zebrafish & humans was ~450 million years ago? A whole genome duplication event (3R) occurred early in the teleost fish phylogeny. Despite this event, zebrafish & humans have about the same number of chromosomes (25 & 23, respectively). #ZebrafishFunFacts 🧪

1 year ago 66 11 2 1
2025 Cellular and Molecular Mechanisms of Toxicity Conference GRC The 2025 Gordon Research Conference on Cellular and Molecular Mechanisms of Toxicity will be held in Andover, New Hampshire. Apply today to reserve your spot.

For more information about the 2025 Gordon Research Conference (GRC) and trainee-led Seminar (GRS), please check out our website:
www.grc.org/cellular-and...

We hope you'll join us in August!

1 year ago 2 2 0 0
The Company of Biologists 100 logo to the left and QR code to the right.
 
Portrait of Daniel Gorelick to the left, text to the right
 
100 extraordinary biologists

Daniel Gorelick

Daniel Gorelick is the current Editor-in-Chief of Biology Open, aiming to improve author experience by providing fair and timely decisions on manuscripts. Dan is Associate Professor and Zebrafish Core Director at Baylor College of Medicine, USA, investigating endocrine-disrupting chemicals’ influence on embryonic development.

#100biologists #biologists100

The Company of Biologists 100 logo to the left and QR code to the right. Portrait of Daniel Gorelick to the left, text to the right 100 extraordinary biologists Daniel Gorelick Daniel Gorelick is the current Editor-in-Chief of Biology Open, aiming to improve author experience by providing fair and timely decisions on manuscripts. Dan is Associate Professor and Zebrafish Core Director at Baylor College of Medicine, USA, investigating endocrine-disrupting chemicals’ influence on embryonic development. #100biologists #biologists100

Our next extraordinary biologist this week is Daniel Gorelick, current Editor-in-Chief of @biologyopen.bsky.social and Associate Professor at @bcmhouston.bsky.social, USA. To know more about Dan’s visions for BiO, read this Editorial: doi.org/10.1242/bio.....
#100biologists

1 year ago 11 8 1 1
18th Zebrafish Disease Models Society Annual Conference (ZDM18), October 13 - 15, 2025, Boston University, Boston, MA - Meetings - Confluence

[Meeting]
18th Zebrafish Disease Models Society Annual Conference (ZDM18), October 13 - 15, 2025, Boston University, Boston, MA

#zebrafish

1 year ago 3 3 0 1

Your regular reminder that the US air & water pollution laws passed in the 60s & 70s -- and the elaborate federal bureaucracy created to administer them -- constitute one of the most successful gov't interventions in history. WILDLY successful. The envy of the world.

1 year ago 11587 2903 195 120
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We’ve landed on BlueSky!

Excited to join the conversation and bring you the latest SOT news, toxicology updates, and more! Stay tuned for insightful research, event highlights, ways to connect with the SOT community, and more! #Toxicology #ScienceMatters #SOT

1 year ago 10 2 0 1
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Nature Story "Revealed: NIH research grants still frozen despite lawsuits challenging Trump order"

(with non-paywalled link)

archive.ph/7h6Im

1 year ago 180 102 9 18

Just my 14 yo who has a bet with his aunt for 25 cents on the eagles….

1 year ago 1 0 0 0
Image of a mummichog (Fundulus heteroclitus). Image credit to Julia Wood at NCFishes.com

Image of a mummichog (Fundulus heteroclitus). Image credit to Julia Wood at NCFishes.com

Toughest fish on Earth? Mummichogs are a euryhaline species, which means they can survive a range of salinities from freshwater to water that has 110g salt/L. Heralded as the first fish species in outer space, they even evolved resistance to toxic chemicals that would kill other fish. #TeleostTalk 🧪

1 year ago 37 10 0 0

This is really bleak, they're attacking all animal research with the ranking Democrat, Shantel Brown, agreeing with Nancy Mace. Brown goes on to state that AI and 3D printing give us "better and more accurate results" compared to actual biology.

1 year ago 360 119 18 44

A depressing question with a lot of great answers. We need #devbio to understand birth defects, cancer, stem cell biology (and the resultant therapeutics) and so much more. And, frankly, because it's just amazing how a single cell can make a complex organism.

1 year ago 14 4 1 0

Right here. I'm fascinated by how it all manages to go well, but also how it can go wrong. If we can bring answers to any families dealing with congenital anomalies, it will be worth it.

1 year ago 6 2 1 0

Same.

1 year ago 0 0 0 0

I'm thrilled to announce that our paper describing Marigold, a free machine learning-based webapp for zebrafish behavioral analysis, is officially published! Marigold features a user friendly graphical user interface to enable training of a neural network for analyzing behavioral recordings.

1 year ago 102 30 7 4
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Multidimensional library for the improved identification of per- and polyfluoroalkyl substances (PFAS) - Scientific Data Scientific Data - Multidimensional library for the improved identification of per- and polyfluoroalkyl substances (PFAS)

We are so excited to share our latest manuscript containing a multidimensional PFAS database with LC retention times, IMS collision cross sections (CCS) and MS characteristics for 175 PFAS and their 281 resulting ion types! We hope it helps others!
www.nature.com/articles/s41...

1 year ago 23 6 0 0
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Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease?

I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵

1 year ago 320 118 6 10
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Scientists at NIH can’t purchase supplies for their studies after Trump administration pauses outside communications | CNN Scientists at the National Institutes of Health have been told the communications pause announced by the Trump Administration earlier this week includes a pause on all purchasing, including supplies f...

Instead of lowering prices, the Trump Administration is disrupting the work of researchers who are studying life-saving medicines and treatments.

1 year ago 443 191 15 17
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Trump's NIH Freeze Puts Scientific Research at Risk America’s best scientific minds are scrambling to determine the impact of the disruption.

Excellent perspective by @lisamjarvis.bsky.social @bloomberg.com on the deep freeze at NIH

1 year ago 220 93 5 6
The Trump administration has imposed a range of restrictions on the National Institutes of Health, affecting meetings, travel, hiring, funding, and communications.

The Trump administration has imposed a range of restrictions on the National Institutes of Health, affecting meetings, travel, hiring, funding, and communications.

The Trump administration has canceled meetings and frozen hiring at the NIH.

In today’s episode, @casey_crownhart joins us to discuss this and other other big science stories of the week. Plus, what is a meme coin?

Listen here 🎧: https://buff.ly/3Mut28J

1 year ago 746 168 59 15

If you had a study section or similar NIH travel canceled, or indeed if you have not, can you reply with the dates of the meeting and whether it's on or not? Would be good to get a sense of what time period this applies to for now (esp if NIH is muzzled and can't announce it...)

1 year ago 49 19 6 2