📢 To all healthcare professionals seeing patients with NCDs: here’s a set of recommendations from our ACTIVATE consensus for how to assess, prescribe and promote #physicalactivity in clinical practice.
Link of paper bjsm.bmj.com/content/earl...
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@stskou.bsky.social @exerciseworks.bsky.social @erc.europa.eu @sdu.dk @sduiob.bsky.social @natmed.nature.com @progrez.bsky.social
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Thank you for reading this Thread!
If you found it interesting, please share it!
Follow my profile @abricca.bsky.social for more on #exercise and #physicalactivity science
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Blood pressure benefits look promising, but we still need more research to understand how exercise therapy affects other physiological markers in this complex population.
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Combined with the primary MOBILIZE results—showing improved HRQoL at 12 months—this adds to the evidence that exercise therapy is a valuable component of care for people with multiple long‑term conditions.
www.nature.com/articles/s41...
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Key finding:
👉 The programme lowered systolic blood pressure.
No meaningful changes were seen in blood sugar, cholesterol, or inflammatory markers.
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We looked at:
• systemic low‑grade inflammation
• glycaemic control
• lipid profiles
• blood pressure
Compared the programme + usual care vs usual care alone.
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We ran a secondary analysis of the MOBILIZE trial to see whether a 12‑week personalised exercise therapy + self‑management programme could improve physiological markers in people living with #multimorbidity.
🧵 www.nature.com/articles/s43...
Increases in MVPA of 5 min/day might prevent up to 6% of all deaths in a high-risk approach and 10% of all deaths in population-based approach.
Reducing sedentary time by 30 min/day might prevent a smaller, but still meaningful, proportion of deaths.
www.thelancet.com/journals/lan...
Many thanks--appreciate it!
I’m very pleased to have the opportunity to continue researching & educating students about the pros and cons of #exercise and #physicalactivity as an Associate Professor at @sduiob.bsky.social
Connect if you have a keen interest in exercise & physical activity for chronic conditions 🙏
🌍 We tested whether a structured exercise and education program could improve HRQoL in people with multimorbidity.
✅ Key finding: Participants in the exercise program had better HRQoL at 12 months compared to usual care.
👉 Full study in @natmed.nature.com www.nature.com/articles/s41...
To dispel the misconception that exercise therapy wears down knee cartilage, clinicians should proactively address these concerns when treating patients with knee #osteoarthritis
open.spotify.com/episode/4JVh...
Exercise therapy and self-management support are more effective than usual care alone in improving health-related quality of life at 12 months in adults with multimorbidity, without compromising safety. #multimorbidity
@erc.europa.eu @natmed.nature.com @sdu.dk
🧵
www.nature.com/articles/s41...
Managing #multimorbidity (two or more chronic health conditions) is one of the biggest challenges in healthcare today. It affects daily life, mental wellbeing, and overall functioning.
We have some good news www.nature.com/articles/s41...
@exerciseworks.bsky.social 🙏
The most effective #digital health interventions for promoting #physicalactivity in individuals with chronic conditions include #exercise combined with self-management, delivered via mixed technologies, or #web #app platforms.
pubmed.ncbi.nlm.nih.gov/40639802/
@ispah.org
Even small increases in moderate-to-vigorous physical activity (MVPA) appear to be associated with low-grade inflammation in individuals with multimorbidity.
onlinelibrary.wiley.com/doi/10.1002/...
Secondary analysis of the #MOBILIZE trial published Nature Medicine lnkd.in/eHQ3kxUU
Getting ready for #ECSS
I’ll be talking about exercise for people with multiple chronic conditions and its impact on inflammation, lipids, blood pressure, triglycerides, and cholesterol.
From a secondary analysis of the #MOBILIZE trial.
www.nature.com/articles/s41...
The Illusion of Simplicity in Therapeutic Exercise
Therapeutic exercise requires personalization, supervision, and continuous adaptation.
Read how we took this into account in our Nature Medicine paper www.nature.com/articles/s41...
#Exercise continues to be the best medicine. A personalized exercise therapy and self-management support program is more effective than usual care alone in improving health-related quality of life at 12 months in adults with multimorbidity @naturemedicine.bsky.social www.nature.com/articles/s41...
Dopo 12 mesi, chi ha seguito il programma (terapia fisica e supporto all'autogestione) ha riportato una qualità della vita relativa alla salute migliore rispetto a chi ha seguito solo le cure abituali, senza ⬆️ i rischi per la salute in persone affette da più patologie croniche. 1/2
New research from the MOBILIZE project, just published in Nature Medicine, shows that an exercise therapy + self-management program = better quality of life for people with multimorbidity.
www.nature.com/articles/s41...
#Science #Multimorbidity #Healthcare #NatureMedicine #MOBILIZE
Necessari ulteriori studi di conferma per indagare anche la rilevanza clinica di tale differenza tra i gruppi. Ottimo lavoro @abricca.bsky.social e considerate caldamente l'esercizio fisico come uno dei "farmaci" più potenti per la nostra salute: un investimento per il futuro! 2/2 💪🏼🔥
Grazie @mattscie.bsky.social per contribuire a diffondere questo messaggio!
Il nostro trial #MOBILIZE è il primo che dimostra che si può migliorare la qualità di vita in questi pazienti 🤞
La strada è ancora lunga ma la direzione è giusta!✅
www.nature.com/articles/s41...
Exercise therapy - still too underrepresented in many countries and in health providers catalogues…
www.nature.com/articles/s41...
9/10 Thanks for reading this thread and don't forget to read the full text of the paper for more info.
If you find it useful please share it!
Follow my profile @abricca.bsky.social for more on exercise and health in people with chronic conditions.
8/10 The takeaway:
While more research is needed to understand the full impact, this study gives hope that tailored exercise therapy and self-management programs can improve life for those living with multimorbidity. #MOBILIZEtrial #multimrobidity
7/10 So what does this mean?
A personalized mix of exercise therapy and self-management support might help people with multiple chronic conditions feel better—without adding risk.
