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Posts by Patrick Moynihan

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Facultative predation expands the ecological repertoire of Streptomyces | mBio Soil is a rich environment for microbes, where they compete for space and resources. Streptomyces bacteria are well known for their ability to synthesize natural products, particularly antibiotics, th...

This is one of the cooler papers I have seen in a while: journals.asm.org/doi/10.1128/...

20 hours ago 3 1 0 0
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Chemoproteomic Elucidation of β-Lactam Drug Targets in Mycobacterium abscessus The pathogen Mycobacterium abscessus (Mab) can cause severe and difficult-to-treat chronic lung infections. Despite the rising incidence and clinical concern of Mab infections, treatment options are l...

New work from my team: pubs.acs.org/doi/10.1021/...
We used probes to ID targets of carbapenems in M. abscessus. 17 targets active in both carbon starved and replicating cultures. Includes validation of 9 targets. Part of a special issue ("NTM Pathogens – Biology, Infection, and Drug Discovery).

1 day ago 5 3 0 0

Lovely to visit. Thanks for listening!

6 days ago 3 0 0 0
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Wonderful to have @pmoyniha.bsky.social from Western University, Canada (hosted by @lislowe.bsky.social) giving a @mhd-newcastle.bsky.social seminar @medicalsciencesncl.bsky.social @newcastleuni.bsky.social #mycobacterium #tb #cellwalls

6 days ago 21 2 1 1

Each publication in a #Microbio26 journal helps fund 4 student travel grants. Please publish with us if you can!

1 week ago 22 15 0 1

Beautiful!! Will have to visit some time.

1 week ago 0 0 1 0
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Always nice to have the chance to visit a UNESCO site. Giant’s Causeway, NI.

1 week ago 12 0 2 0
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Looking forward to attending the @microbiologysociety.org annual general meeting in Belfast. I'll be speaking in the Mycobacteria session on Tuesday. Also plenty of posters from the group!

1 week ago 6 1 0 0

If you are working on staphylococci you might want to travel to Banff this September

banff.isssi2026.com/event/ISSSI/...

1 week ago 0 2 0 0

Track saw?

2 weeks ago 0 0 0 0

But I agree. It should start from the “normal” and then reinforce by teaching the exceptions.

3 weeks ago 1 0 0 0

Biology always there to spoil rules. Leaderless transcripts quite common in mycobacteria.

3 weeks ago 1 0 1 0
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Genomic epidemiology of Salmonella and Campylobacter in poultry production: Quantifying the contribution of primary breeders | PNAS The US broiler production system processes over 9.3 billion chickens annually through a highly integrated pyramid structure where two primary breed...

www.pnas.org/doi/10.1073/...
If you ever need lto be convinced by how bad the "Contributed by" track is at @pnas.org ...

Only author: David Lipman, handling editor: David Lipman. Only integrity-free person not embarrassed by such a paper: David Lipman.

Even uses "I did" in the abstract. Shameful.

3 weeks ago 8 3 0 0
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Please Repost 🔄

Global Staphylococcus research community is heading to the Canadian Rockies!

Join the 20th International Symposium on Staphylococci and Staphylococcal Infections
📅 September 20–24, 2026

📍 Banff Centre for Arts and Creativity, Banff, Canada

#ISSSI2026
#Staphylococcus

4 weeks ago 11 18 2 1

PSA: If you are thinking about putting a 3D data plot into an output that will primarily be viewed in 2D, don't.

3 weeks ago 2 0 0 0

I should add this is just the tip of the iceberg. Plenty more to come on this story from our group, @proftracypalmer.bsky.social, @lislowe.bsky.social and others. There is such an astonishing diversity of toxins in these bacteria and so much we don't yet fully understand.

3 weeks ago 9 0 0 0

A Type VII-secreted toxin enables inter-mycobacterial competition www.biorxiv.org/content/10.64898/2026.03...

3 weeks ago 6 5 0 0
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*objectively.

well done Sam.

3 weeks ago 2 0 0 0
Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

Cartoon representing the mycobacterial oxidative phosphorylation system, including cytochromes, NDH-2, and ATP synthase. Taken from Figure 1 of the article.

#Microbiology

The anti-tuberculosis drug bedaquiline targets the mycobacterial ATP synthase, but how that leads to bacterial death is unclear

Here the authors clarify how bedaquiline works

@jnblab.bsky.social @morwan.me
#TBSky #antibiotics #AMR

http://dlvr.it/TQjZ0W

2 months ago 37 21 3 0

We've been we've been working on this for quite a while now (hopefully published soon). Grateful to @proftracypalmer.bsky.social for concinving me & @lislowe.bsky.social that mycobacteria produce inter-bacterial toxins. Team science, led by @sambenedict5.bsky.social www.biorxiv.org/content/10.6...

3 weeks ago 48 26 4 6
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CIHR Project Grant Cycle Restructuring Dear colleagues, Below you will find a draft letter regarding the proposed transition to a single annual CIHR Project Grant competition, and to invite you to sign on if you are in agreement with its c...

With the rumblings around CIHR wanting to move to one cycle per year not going away, in consultation with a diverse stakeholder group, we have put together a letter for CIHR leadership. Please consider signing this letter and share/RT: docs.google.com/forms/d/e/1F... @cannabrain.bsky.social

3 weeks ago 34 31 4 2

I feel that today 🤣😂

4 weeks ago 0 0 1 0

Thanks. Same!

4 weeks ago 1 0 0 0

This job really knows how to ruin your day sometimes.

4 weeks ago 3 0 3 0
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Research Fellow (Postdoctoral) at University of Birmingham Explore an exciting academic career as a Research Fellow (Postdoctoral). Don't miss out on other academic jobs. Click to apply and explore more opportunities.

Two post-doctoral positions open in our lab. We're looking for people with expertise in molecular microbiology and/or genome-scale tools. Initially 3 yrs, posts could be extended for upto 8 yrs. If you'd like to know more about us take a look at www.graingerlab.com

www.jobs.ac.uk/job/DQY475/r...

4 weeks ago 27 52 0 1
QR code to access 'Structural diversification of phage tail fibres enables recognition of diverse type IV pili'

QR code to access 'Structural diversification of phage tail fibres enables recognition of diverse type IV pili'

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New paper showing how tailed #phages recognize diverse #Pseudomonas #T4P! Outstanding work by PhD candidate Ikram Qaderi, building on work started a decade ago during my sabbatical in the McArthur lab and in collaboration with the Guarné lab, now at #McGill. @mcmasteriidr.bsky.social

1 month ago 33 13 2 0

When it rains myco publications in pours myco publications!
Now out in PNAS tinyurl.com/2a6833n4
When @zestytoast.bsky.social accidentally isolated the long-chain acyl-CoA carboxylase, we quickly realized we were looking at a fascinating machine essential for building the mycobacterial membrane...

1 month ago 46 17 2 0
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Out now in EMBO J ahead of World #TB day!
Our friends at the TB Drug Accelerator identified EtfD as a high-priority target for fast acting treatments so @courbongautier.bsky.social jumped into action.
Our EtfD assay & struct are already being used to help find new therapeutics
tinyurl.com/3cb2j5k9

1 month ago 32 8 0 0

Ah gotcha. Best of luck and welcome to Canada when you get here!

1 month ago 1 0 1 0

No judgement whatsoever. We moved from the UK to Canada despite much better funding options there. Just sharing that the situation in Canada for research is currently not great.

1 month ago 1 2 1 0