What an amazing #Fungal26✨ Feeling very inspired– thank you to everyone who shared science and ideas! Thank you to the organisers for my poster award, @gensocuk.bsky.social for sponsoring my attendance and huge thank you @talbotlabtsl.bsky.social for these past years! I will miss the Talbot Lab.
Image from Claude ai
Shout out to the myco-skeeters 🦋 at #fungal26
It's been fun live posting with you!
@germhuntermd.bsky.social @talbotlabtsl.bsky.social @audreykward.bsky.social @angusb.bsky.social @hyphaltip.bsky.social @uehlinglab.bsky.social
Césarée Morier-Gxoyiya @cesaree-mg.bsky.social asks what is causing the rise of wheat 🌾 stem rust?
Is the rising temperature 🥵 in the UK to blame for this increase?
Unlikes the rusts, Césarée will end this cycle (aka her PhD) looking for a postdoc
#fungal26
Megan McDonald speaking at the Fungal26 conference.
The one and only @mcdonaldmeganc.bsky.social at #Fungal26 talking about ToxA’s journey throughout the stars in different Starships!
Starships in fungi are so intriguing & have clearly had enormous (& diverse) impacts on genome evolution. @mycomile.bsky.social So many questions- the catalytic mechanism of YR Captains, target-site selection, how they move between fungi? (anastomosis/ role for parasexuality?) Amazing #Fungal26
Want to hear about gene regulation driving pathogenicity in the rice blast fungus? Come to my talk this afternoon at the Cell Wall Synthesis and Remodelling session at 16:40! Or my poster tonight! 🍄 #Fungal26
AI-tools to study fungal effector function introduced by @ahbucknell.bsky.social #Fungal26 #FungalAI @thesainsburylab.bsky.social
Phosphoproteomic analysis of TOR signalling during appressorium development of Magnaporthe @mattwengler.bsky.social #fungal26
Magnagenes- an open science resource for the Magnaporthe research community with many new functions is being developed
@thesainsburylab.bsky.social
by Neha Sahu
#Magnafest26 #Fungal26
I’ll be talking today at the #Fungal26 concurrent session: AI in Fungal Research. I’ll be presenting on protein design in M. oryzae at 15:20 in the Fred Farr Forum.
I’ll also be presenting my poster (#651A) tonight - come say hi!
Goodbye #Magnafest26, and hello #Fungal26!
A big thanks to @osesmir.bsky.social and @frankmenke.bsky.social for organising this year’s meeting, as well as all the presenters!
Looking forward to seeing the research in the greater fungal research community at FGC!
Fabio Dos Santos Barbosa on dissecting the Sln1 turgor-sensor pathway and its role in appressorium function. #Magnafest26 #Fungal26 @thesainsburylab.bsky.social
Here is our very own 'PhosphoJave' Bautista introducing his family of phosphorylated fungal effectors and their potential regulation #Magnafest26 #Fungal26
Euan Cawston on investigating the role of Mst7 and identifying potential scaffolds of the Pmk1 MAPK pathway #Magnafest26 #Fungal26 @thesainsburylab.bsky.social
En route to #Fungal26 with the @talbotlabtsl.bsky.social group
Out in New Phytologist!
The annotated blueprint: integrated functional genomic resources for a model tetraploid wheat cv. Kronos 🌾
chromosome-scale genome, high-conf annotations, manually curated 1000+ NLRs, ~3000 remapped datasets
🔗 doi.org/10.1111/nph....
#Plants #Genomics #FunctionalGenomics
One week left to apply for the PhD position in my group in Stockholm!
So happy to have @mcdonaldmeganc.bsky.social with us for the day!
Delighted that our work on the Sanctuary Starship #transposon is now published! A big thanks to all co-authors, especially to the ever-amazing @mcdonaldmeganc.bsky.social for her mentorship!
doi.org/10.1128/mbio...
Yes! During my extremely brief foray into Rust, the error messages (there’s been a lot!) have been extremely helpful.
I’m hoping to put in some proper time into learning Rust soon. Do you have any advice for those who have only worked with high-level languages?
I talk a lot about Rust for building high-perf (& even non-perf critical) software, & scientific software in particular. I often discuss what's interesting to me, but wanted to offer the chance to those interested for me to answer their questions about Rust in science. Fire away with questions!🧬🖥️
There’s plenty of plotting libraries now, I’ve settled on Makie - and am quite frankly loving it.
I’ve heard terrible things about the runtime startup speeds in the past. For me now it’s completely usable, but anecdotally Python is noticeably faster.
For me, the biggest issue is error message!
I’ve switched to Julia now for a lot of the tasks you’ve mentioned, having previously used a combination of Python and R. Can really recommend it for most of these uses, but only used Quarto rather than Jupyter.
I’ve also thought about giving Rust a try, so looking forward to this thread!
You designed binders for your favourite protein and wish there was a way to experimentally screen them within 24h w/ only a set of pipettes and a plate reader?
Check out our Cell-Free 2-Hybrid approach (CF2H)
Full post: tinyurl.com/48cz5nb6
Preprint: www.biorxiv.org/cgi/content/...
#2025ISMPMI Agnus Bucknell of the Talbot lab gives an exciting presentation to engineer fungal effectors recognizing immune sensors based on Pik1. Great and clear talk.
#2025ISMPMI Want to know about transcriptional regulation driving pathogenicity in the blast fungus? Come to my poster (P-156) session today!
From 13:30 to 15:15 🌾
A man giving a presentation at a lectern with an MPMI logo
@angusb.bsky.social wants to engineer plant resistance proteins (NLRs) from scratch.
Can we create protein domains to integrate into NLRs to catch pathogen effectors? New tech makes this possible now.
Chose Magnaporthe and Fusarium effectors as targets - many steps later, it worked!
#2025ISMPMI
@adamrbentham.bsky.social
Sounds great - see you all there!
Scientific presentation with a PowerPoint slide showing a global map with sample locations and ToxB genotype
@mcdonaldmeganc.bsky.social presents on the ToxB fungal effector. Pacbio long-read sequencing ~doubles detection of transposons compared to short-read. Helpful for finding where the multiple copies of ToxB -flanked by TEs- are throughout the genome. Sometimes in tandem copies! #2025ISMPMI