A disease model resource reveals core principles of tissue-specific cancer evolution - Nature The Mouse Cancer Cell line Atlas (MCCA) provides major advances towards a mechanistic understanding of cancer genomes.

new out in Nature www.nature.com/articles/s41...

Excellent study showing that the plasminogen system regulates immune suppression in pancreatic cancer. Congratulations Chiara!

🚨 Our new #preprint is out!
doi.org/10.1101/2025...
We used #PerturbMap spatial functional genomics in pancreatic cancer to track tumor clone dynamics and uncover how extracellular factors like Serpine1 and Serpinb2 drive immune evasion. 🧵 (1/8)