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Posts by Dan Sprockett

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Computational Biology Program Scientist MIT - Computational Biology Program Scientist - Cambridge MA 02139

Interested in a *staff computational scientist* position? We are looking for an experienced computational biologist (ideally with microbiology experience) to support published packages while also driving new research. Pay range $73k-$111k w excellent benefits. careers.peopleclick.com/careerscp/cl...

9 hours ago 39 69 1 0
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REMINDER - Abstract submission deadline for MEEHubs2026 is April 19! Get you abstract in and present at one of the hubs August 3-5, 2026✨You'll be in great company! We have a fantastic lineup of speakers‼️

Links and more info here: meehubs.org

2 weeks ago 8 12 0 3
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I am excited to share our latest paper, Uniform bacterial genetic diversity along the gut, now out in Nature Communications! www.nature.com/articles/s41.... (1/n)

3 weeks ago 69 32 3 1
Image of the cover of the 1st volume of ISME Host Microbe a new official journal of the International Society for Microbial Ecology. Cover images shows a plant stomata with bacteria around and entering.

Image of the cover of the 1st volume of ISME Host Microbe a new official journal of the International Society for Microbial Ecology. Cover images shows a plant stomata with bacteria around and entering.

Excited to announce our new journal from @isme-microbes.bsky.social ISME Host Microbe is live and now accepting submissions. Look forward to receiving your papers! #Microsky 🧫 🦠

1 month ago 120 82 3 1
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Environmental microbiota transfer from forest soil into urban homes: a proof-of-principle study - Microbiome Background Urban lifestyles are characterized by reduced encounters of environmental microbe stimuli that activate immunoregulatory pathways. This has been linked to an increased risk of inflammatory ...

If I had only realized that my kids were running experiments all weekend!

"Microbiota transfers were performed with repeated seeding of forest soil onto rugs placed in the home entryway."
link.springer.com/article/10.1...

3 weeks ago 7 0 1 0
YouTube Share your videos with friends, family, and the world

This is great, thank you! The National Science Board said there would be more information about this year's GRFP today, but I haven't seen anything yet: www.youtube.com/live/qacDcWu...

As an aside: You an I are probably in a very small cohort of people who went from Kent State to Stanford+Harvard.

1 month ago 1 0 1 0
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Students, faculty mystified as NSF turns back applications for prestigious fellowship program Applicants to a prestigious National Science Foundation fellowship program say many submissions have been mysteriously “returned without review.”

The lack of information about this has been incredibly frustrating:

Students, faculty mystified as NSF turns back applications for prestigious fellowship program
www.statnews.com/2026/02/11/n...

Another excellent piece by @jonathanwosen.bsky.social at @statnews.com

2 months ago 2 0 0 0
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New Preprint 📢 from our team 🔎 Critical assessment of #intratumor and #low #biomass #microbiome using #longread sequencing

Some studies suggest bacteria 🦠 live inside tumors and influence cancer treatment. But there’s also been a major #debate: in these very​ low-microbe tissue samples, how much 1/

2 months ago 43 19 2 0
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New preprint from my lab (with Arya Kaul, @fernpizza.bsky.social, and @brinda.eu), in which we explore new genes hitchhiking on the beneficial deletion that fused them together, and find them in the LTEE, M. Tb/bovis, and across the bacterial tree of life

3 months ago 87 36 5 3

Sometimes you find that you need a tool that does a specific thing, and the universe just manifests it...

(...or maybe it was years of hard work by very clever colleagues).

3 months ago 3 0 0 0
Kara Marshall PHD-History of Science in America - Trilogy at Tehaleh 04/27/25
Kara Marshall PHD-History of Science in America - Trilogy at Tehaleh 04/27/25 YouTube video by Steve Lawson

I think everyone can relate to the importance of science for healthcare, and I’ve been sharing these slides for people to use and adapt with their own stories! youtu.be/BY_SFgi-Cig

4 months ago 6 3 1 0
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Special Research Seminar – 12/10/2025 Daniel Sprockett from Wake Forest University School of Medicine will be visiting Duke to present some of his research to…

I'll be @dukemedschool.bsky.social next week presenting my research: “Ancient Partnerships, Modern Insights: Tracing the Assembly, Transmission, and Evolution of Mammalian Gut Microbes”.

sites.duke.edu/microbiome/2...

Come say Hi! @duke-university.bsky.social #microbiome

4 months ago 6 0 0 0
Human Microbiome: From Models and Mechanism to Medicine | Keystone Symposia Join us at the Keystone Symposia on Human Microbiome: From Models and Mechanism to Medicine, January 2026, in Banff, with field leaders!

Poster deadline for the Keystone Microbiome Meeting in Banff is December 30th www.keystonesymposia.org/conferences/...

Will be a great meeting focused on human microbiomes, spanning basic, mechanistic, and applied. Organized by myself, @amibhatt.bsky.social , and Harry Sokol. Join us!

4 months ago 11 12 0 0
STREAMS guidelines: standards for technical reporting in environmental and host-associated microbiome studies - Nature Microbiology This Consensus Statement presents the standards for technical reporting in environmental and host-associated microbiome studies (STREAMS) guidelines.

Proud to have contributed to this important work!

STREAMS guidelines: standards for technical reporting in environmental and host-associated #microbiome studies. www.nature.com/articles/s41... @natmicrobiol.nature.com

4 months ago 5 3 0 0
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GitHub - COMBINE-lab/mim: A small, auxiliary index to massively improve parallel fastq parsing A small, auxiliary index to massively improve parallel fastq parsing - COMBINE-lab/mim

Ok; mim (github.com/COMBINE-lab/...) preprint submitted! Excited for folks to see it and share thoughts. The key takeaway; mim allows the quick, one-time, building of a small auxiliary index that then allows scaling gzipped FASTQ parsing linearly in # of threads. 1/2

4 months ago 27 13 1 3
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"The Assembly, Evolution, and Clinical Implications of the Gut Microbiota in Early Life" With Daniel Sprockett, PhD, MSc | Center for Gastrointestinal Biology and Disease

If anyone happens to be around UNC Chapel Hill this week, I'll be speaking on Tuesday: www.med.unc.edu/cgibd/event/... @microbiomeunc.bsky.social #microbiome

7 months ago 5 5 1 0
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Prehistoric Global Migration of Vanishing Gut Microbes With Humans The gut microbiome is crucial for health and greatly affected by lifestyle. Many microbes common in non-industrialized populations are disappearing or extinct in industrialized populations. Understand...

Excited to share a new preprint w/ the Sonnenberg lab, led by Matt Carter, @zzzhiru.bsky.social & @mattolm.bsky.social. We analyzed the microbiomes of two non-industrialized populations from opposite sides of the globe to try to reconstruct the recent evolutionary history of our gut microbiota.

8 months ago 66 21 2 0
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Prehistoric Global Migration of Vanishing Gut Microbes With Humans The gut microbiome is crucial for health and greatly affected by lifestyle. Many microbes common in non-industrialized populations are disappearing or extinct in industrialized populations. Understand...

Check out this incredible analysis!

Prehistoric Global Migration of Vanishing Gut Microbes With Humans
www.biorxiv.org/content/10.1...

8 months ago 11 6 0 0
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Junior, Assistant, or Associate Specialist – Xue Lab University of California, Irvine is hiring. Apply now!

The Xue lab at UC Irvine is looking for a staff scientist to support our work investigating how microbes interact and evolve in the gut microbiome! Open to a wide range of previous experience levels, see ad for more.
recruit.ap.uci.edu/JPF09601

9 months ago 117 112 0 3
Garud Lab

I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!

9 months ago 84 99 1 4

Looks like it'll be a good one!

8 months ago 3 0 0 0

Excited to share the Compendium Manager -- our new tool for scaling bioinformatics pipelines! Launch thousands of analyses, track progress, and maintain reproducibility. Developed by @richabdill.com. Check it out: arxiv.org/abs/2505.11385

11 months ago 16 4 1 0
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Mobile integrons encode phage defense systems Integrons are bacterial genetic elements that capture, stockpile, and modulate the expression of genes encoded in integron cassettes. Mobile integrons (MIs) are borne on plasmids, acting as a vehicle ...

#NatureMicroPicks

Microbial integrons in focus 🦠🧬

Two studies showing microbial integrons encoding phage defense systems

#MicroSky

www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

11 months ago 40 14 1 0

One thing I think I want to ban entirely is using AI-generated citations. You can't really cite something if you haven't read it yourself.

And even if AI hallucinations get better, I think the risk is far too great.

11 months ago 1 0 0 0

One thing that comes to mind that could be very positive is assistance with coding and data analysis. But how do I ensure that lab members have a deep understand of how every line/function works?

11 months ago 2 0 0 0

A very open-ended question:

Has anyone developed a lab policy for for AI use in their biomedical research that they'd be willing to share?

Have people even thought about defining what should be allowed/encouraged, and what should be outright banned?

Please share with anyone who might have ideas.

11 months ago 4 0 2 0
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Ecologically expanding the One Health framework to unify the microbiome sciences | mBio Microbiome research rapidly expanded in the last two decades, with nearly 200,000 peer-reviewed articles that use the word “microbiome” and significant microbial lineage discoveries reshaping the evol...

🔬 New Perspective in mBio (@asm.org)!

We call for a shift from disease surveillance to microbial stewardship, and highlight testable, cross-system hypotheses to unravel central rules of microbial life–spanning multiple scales, taxa, and environments. 🦠🌎
journals.asm.org/doi/10.1128/...

11 months ago 11 8 0 1
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‘We can change diet to generate a healthier microbiome and a healthy individual’ Microbiologists Justin and Erica Sonnenburg are working to understand the complex microbial community that resides within the human gut and its potential for helping people live healthier, longer live...

From 2 of my favorite scientists:
“We are deeply concerned about the current funding climate. When we think about new professors or postdocs starting their own labs, we worry that funding challenges could easily result in losing a generation of talented scientists.”
news.stanford.edu/stories/2025...

11 months ago 7 5 0 0
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Do people in the same household share strains when they have the same species?

How many cells transmit when a strain is shared?
Can strain composition be dynamic when species composition is stable?

We answer these and related questions for the facial skin microbiome in our latest paper.

🧵[1/10]

11 months ago 140 67 4 1
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Register Register for your free STAT account.

This is exciting! Top reporting on Science, Biotech, Health Policy, and Public Health news.

Wake Forest University School of Medicine affiliates can access @statnews.com for the next 2 weeks!

Visit www.statnews.com/register/ & enter a valid @wakehealth.edu email address

@wakeforest.bsky.social

11 months ago 0 0 0 0