Key points from the Review Article "GLP-1 Receptor Agonists"
A new review by Clifford J. Rosen, MD, and Julie R. Ingelfinger, MD, describes a new generation of treatment with GLP-1 receptor agonists for persons with obesity with or without diabetes or prediabetes. Learn more: nej.md/4sUFlys
@tuftsmedschool.bsky.social @cjrosenlab.bsky.social
@cjrosenlab.bsky.social - welcome
go.bsky.app/N31Rm2w
We are thrilled to welcome Ruixin Feng, medical student at University of New England, to the Rosen lab! Ruixin has a strong interest in understanding how weight loss impacts bone health and will be working under the guidance of @carolynchlebek.bsky.social.
What are the mechanisms of weight loss induced bone loss? Check out our recent review of the current literature on the mechanistic pathways and clinical consequences of weight loss–induced bone loss:
doi.org/10.1038/s414...
Huge congratulations to Dr. Victoria DeMambro, recipient of the 2025 Soft Bones Maher Family Research Grant for hypophosphatasia! This grant will support her research to understand underlying causes of muscle weakness & chronic fatigue symptoms in adult HPP patients
lnkd.in/eutXHxNK
Let's do it! @asbmr.bsky.social do you manage a bone starter pack?
Congratulations to lab member, Linyi Liu, on his recent promotion to Staff Scientist I! 🎉
Shoutout to our lab manager, Phuong, for representing the Rosen lab in the MHIR Costume Contest and securing first place!! 🥇🎉
Happy Halloween from the Rosen lab! @demambrove.bsky.social @carolynchlebek.bsky.social
How does calorie restriction change the skeleton in obese mice? Check out our latest paper, out now in Bone. Spoiler: calorie restriction leads to bone loss and shifts the metabolome in the cortex! Congratulations, @carolynchlebek.bsky.social
doi.org/10.1016/j.bo...
New lab photo for the Rosen lab! 📸
Curious about how weight loss strategies affect bone health in patients with obesity? Check out this recent review article published in #JBMR @asbmr.bsky.social
doi.org/10.1093/jbmr...
Earlier this month, medical student Stephanie Lam represented the Rosen lab at the University of New England College of Medicine's Fall Research Forum! Stephanie shared her findings on changes to animal behavior during caloric restriction, generated through her work with @carolynchlebek.bsky.social
We are excited to have Samuel Rubin continue in our lab as a Research Assistant I! Sam started with us as a part-time learner and is now managing an independent research project - go, Sam! Stay tuned to hear about all his exciting research.
Huge congrats to lab member @demambrove.bsky.social on a fantastic talk this morning at #ASBMR2025! 🎉🦴 if you didn’t get a chance to ask your question at the session, be sure to find Dr. DeMambro at this meeting! @asbmr.bsky.social
Huge thanks to @natalieasims.bsky.social for featuring Dr. DeMambro’s abstract during this morning’s session! We are also so excited for this presentation! Join us at noon in Room 6E (TODAY!) #ASBMR2025 @asbmr.bsky.social
Planning out which amazing @asbmr.bsky.social sessions you want to hit tomorrow? Be sure to go to Room 6E tomorrow at noon to hear about treating adult HPP mice with Ilofotase Alfa from @demambrove.bsky.social! (Abstract #1020) Plus so many other great rare bone talks in this session! 🦴
Are you at the @asbmr.bsky.social /RBDA Symposium on Rare Bone Diseases? Check out Dr. DeMambro’s poster on Ilofotase Alfa treatment in adult HPP mice, which was recognized by a Pre-Meeting Young Investigator Travel Grant for the top Young Investigators presenting today 🎉
Interested in the role of bone in whole-body energy metabolism? Check out this recent review in @natrevendo.nature.com ! Co-authored by lab leader, Dr. Cliff Rosen 🦴
Calling all #ASBMR2025 attendees! Do you have a stunning image, video, or graphical abstract that reveals the beauty and complexity of the musculoskeletal system?
📣Announcing an image competition!
Proof that beach days are good for #bones!
We love seeing our lab members featured in the MHIR Newsletter! Congrats, again Dr. DeMambro! 🎉
We are SO excited that Dr. Victoria DeMambro successfully defended her PhD 🎉 Dr. DeMambro’s thesis, entitled “Tissue Nonspecific Alkaline Phosphatase: more than a pro-mineralizing enzyme”, focused on hypophosphatasia 🦴
We are SO excited to welcome Dr. Madhura Nijsure @madhura0327.bsky.social to the Rosen lab this week! As a postdoc, she is excited to explore how diet and nutrition influence bone health and homeostasis at the molecular level. Stay tuned for her amazing research!
Can the new wave of GLP1 medications be useful for treating Type 1 Diabetes? Check out this editorial and the associated articles in the @nejm.org to learn more!
evidence.nejm.org/doi/abs/10.1...
Looking for a fun Friday read? Check out our most recent paper exploring the inflammatory responses and lipid metabolism in bone marrow adipocytes after high calorie feeding and fasting in humans! Huge congratulations to Dr. Costa & team for such exciting work!
doi.org/10.3389/fend...
We are excited to welcome #UNECOM student Stephanie Lam to the Rosen lab! Stephanie will be working with @carolynchlebek.bsky.social to understand the effects of calorie restriction on bone and other organ systems.
Congratulations to the @asbmr.bsky.social Harold M. Frost Young Investigator Award recipients! We are excited to see our own @carolynchlebek.bsky.social among the awardees 🎉 Attend the @orssociety.bsky.social Musculoskeletal Biology Workshop to hear from the awardees about their exciting research!
Last week, we said goodbye to Dr. Costa, but we cannot wait to hear about her amazing postdoctoral research ahead at the University of Pittsburgh! Congratulations again to Dr. Costa on a fantastic thesis and research career at MaineHealth! You will be missed!
