🦈🧠2 JOB OFFERS in the brand-new Neuroshark group starting at the Institute of Neuroscience Paris-Saclay (NeuroPSI)?
Lab manager:
www.linkedin.com/posts/idoia-...
Bioinformatician:
www.linkedin.com/posts/idoia-...
Curious about the lab but not your profile? Feel free to contact me
Posts by Mari Sepp
By applying for an MSCA Postdoctoral Fellowship with the University of Tartu, you can access 3 funding pathways: MSCA, ERA Fellowships, and national funding schemes.
Get in touch if interested in brain development, autism spectrum disorders, and single-cell genomics.
ut.ee/en/content/p...
Thrilled to present our comparative study on the evolution of zygotic genome activation (ZGA)!! 🥚🧬
Amazing PhD work of @campobes.bsky.social together with @fedemantica.bsky.social and many collaborators! @melisupf.bsky.social @crg.eu. Thread below 1/15
www.biorxiv.org/content/10.6...
Congrats!
Very proud of this and so cool that enhancer-level models can predict the effect of genetic variation. There is so much personal variation in terms of gene regulation in the human brain, it is fantastic to uncover this thanks to technology (whole-genome sequencing and single-cell multiomics) and AI
Exciting study by @lenakutscher.bsky.social and @doctorpauln77.bsky.social on male bias in medulloblastoma:
“testosterone and the XY genotype cooperate to increase the abundance of specific cerebellar progenitor populations”
Elegant use of Four Core Genotypes mice + recapitulation in organoids
Amazing Margarida and her amazing research. Curiosity and enthusiasm in action 💙
Also out today - A quick intro piece on the role of the cerebellum in cognition. What does it do? How will we find out? This is what @actlab.bsky.social and I think the critical questions are right now. It was fun to write - especially the section on evolution....
journals.plos.org/plosbiology/...
interested in working on sex differences during development and in tumor initiation! come join our lab via the MSCA MasterClass
Inhibitory neurons are among the most transcriptomically diverse class of neurons in the CNS, with some brain regions having 60+ distinct cell types. Do humans share the same repertoire as rodents? Birds? Fish? 1/13
Warm congratulations to The Brain Prize winners 2026, Professor David Ginty and Professor Patrik Ernfors, for their pioneering work on how the nervous system detects and processes touch and pain.
Karolinska Institutet
HHMI
#Neuroscience #BrainPrize2026
A beautiful 😍 review on vertebrate organ evolution - from molecular basis and evolutionary forces to the emergence of novel forms and functions.
It was a wonderful opportunity to reflect on our work on the development of the mammalian cerebellum.
We thank our editors, Alexandra Joyner and James Li!
Special thanks to Henrik @kaessmannlab.bsky.social for his unwavering support and mentorship!
How have concerted and mosaic evolutionary mechanisms shaped the expansion of the human cerebellum?
Our review with @tyamadat.bsky.social and @ioansarr.bsky.social available free till March 29:
authors.elsevier.com/a/1ma2wFzn7a...
Ramsey Najm and I have a joint postdoc position advertised through the @hlsalliance.bsky.social Interinstitutional Postdoc call! Our project proposes to generate better posterior cerebellar organoids to improve fidelity of pediatric medulloblastoma models.
www.health-life-sciences.de/opportunitie...
Hiring a PhD student! 🎓
Looking for a PhD student to work on the prediction of complex diseases by integrating genetics, multi-omics, and electronic health records. Details: genomics.ut.ee/sites/defaul...
Please share with anyone interested!
Some friends and I wrote a review with @biologists.bsky.social !! Together with Esther Becker and Simone Mayer, we explore the state of the cerebellum organoid field and offer practical guidance on getting this model system started in your own lab. journals.biologists.com/dmm/article/...
Congrats to @urmovosa.bsky.social and the international research team behind this achievement, including colleagues at @estbiobank.bsky.social!
Thank you!
I've started my own lab 🎉
PhD/postdoc positions available - reach out if curious about cerebellum evo-devo and autism spectrum disorders.
We’re based at Uni Tartu, Institute of Genomics (home to Estonian Biobank), and funded by @simonsfoundation.org @embo.org, and the Estonian Research Council.
This paper marks the end of a long but rewarding project - and the start of something new (more below👇).
Massive thanks to @kaessmannlab.bsky.social, @ioansarr.bsky.social, @tyamadat.bsky.social, our amazing collaborators @steinaerts.bsky.social, Stefan Pfister, Rüdiger Behr and the entire team! 💙
Big congrats to @kmatlik.bsky.social and all the EMBO Installation Grantees 2026! 👏🎉
TF-MINDI is out! A new method to learn cis-regulatory codes through rich embeddings of TF binding sites. TF-MINDI decomposes motif neighbourhoods, and works downstream of any sequence-to-function deep learning model. We deeply study the enhancer code in human neural development, check out the thread
We are looking for a Postdoc at the Center for Gene Expression in Copenhagen. Deadline for applications is the 11th of January. If you are interested in 3D chromatin, SMC complexes, and super-resolution microscopy, join us. www.nature.com/naturecareer...
Really happy to join NeuroPSI at Paris Saclay to lead a research group funded by an ERC Consolidator grant #ERCCoG . We'll study the origins of the vertebrate brain using shark embryos. 🦈 🧠 Reach out if you are interested in joining the team 🤍
Join us at SMBE26! We are in a golden period for understanding the evolution of gene regulation.
Aged mice and human samples show patterned loss of Purkinje cells in the cerebellum, revealing a spatial signature of ageing that may help explain why motor coordination and behaviour decline over time.
In 2018, Tomasz Nowakowski received our Fellows-to-Faculty Award to jumpstart his new lab. We spoke with him about his research and the Fellows-to-Faculty program, which is open for apps: www.simonsfoundation.org/fellows-to-faculty-alum-...
#ERCCogG granted!!! Immensely grateful for this opportunity. Thanks @erc.europa.eu . Many news coming soon. New lab opening and will be posting positions. 🦈🧠🤍 Go sharkies!