Happiest Birthday @luispedrocoelho.bsky.social!!🎉

#2026 #Birthday #supervisor #memories #Celebrate #BDB @cmrqut.bsky.social #TRI #QUT

Whither PhDs in the Age of Claude? Publication or perish as export discipline

open.substack.com/pub/luispedr...

Links. Tweets. Photos (mid-April 2026) I have created a new section on the substack to contain the Links emails, so you can subscribe/unsubscribe to the Links emails separately from other posts.

Links & Tweets post (plus a picture found on the street)

luispedro.substack.com/p/links-twee...

Unteaching school A lot of what I do with graduate students is what I call unteaching school.

"A lot of what I do with graduate students is what I call unteaching school."

A new substack post

luispedro.substack.com/p/unteaching...

BrisJAMS is back this April and it’s shaping up to be a seriously fun night of science, stories, and good vibes 🧪🧫✨

📅 When: Wednesday, 29 April 2026 | 6:00–7:30pm
📍 Where: The Burrow (Beer Garden Room), West End.
👉 Register via the QR code on the poster!

Yes, we also got better results with multi sample! I have not yet dug into this new preprint, but definitely surprising

This simulation-cum-benchmark study on MAG making by @tkorem.bsky.social & team looks really interesting. Loads of plots and results to work through!

www.biorxiv.org/content/10.6...

The other day, I was listening to a podcast about AI in science and from people's accents while introducing themselves, I knew what everyone was going to say

Very impressive to see all the diversity hidden and generally missed by common approaches!

This, but unironically

(especially so in the Age of Claude - taste is that which is scarce)

Our work on 'hidden diversity' in unbinned contigs is now published in @natmicrobiol.nature.com :

www.nature.com/articles/s41...

See the linked threads for more details!

Bioinformaticians have been writing the same abstract for decades We have always been overwhelmed by the data explosion

We have always been overwhelmed by the current data explosion!

luispedro.substack.com/p/bioinforma...

Bioinformaticians have been writing the same abstract for decades We have always been overwhelmed by the data explosion

Full post includes links to the original papers: luispedro.substack.com/p/bioinforma...

2026

2007

1998

1994 (x2)

1994

1991

1985

1983

1967: "There is a tremendous amount of information regarding evolutionary history and biochemical function implicit in each sequence and the number of known sequences is growing explosively."

— Margaret O. Dayhoff

Bioinformaticians have been writing the same abstract for decades We have always been overwhelmed by the data explosion

We have always been overwhelmed by the current data explosion!

luispedro.substack.com/p/bioinforma...

Monthly median Received to Accepted time (days) at Nature Genetics

Data centers' heat exhaust is not raising the land temperature around where they're built A terrible paper and even worse interpretation is threatening to become common wisdom

Okay folks I've responded to the data center heat island paper. It is the worst study on AI and the environment I've ever read, by far. Thank you to @beijingpalmer.bsky.social for flagging. blog.andymasley.com/p/data-cente...

Urban soils are a small part of the world and lack the glamour of the wilderness or the economic importance of agriculture, but as most people live in cities, they are very important

Our latest preprint using long-read metagenomics reveals massive hidden diversity and function in city soils

🧵

BDB-Lab March 2026 Updates What lurks in urban soil microbiomes

Quarterly updates from the group!

Focus is our latest work on urban soil microbiomes.

They are far richer than might be expected. Our latest work using long-read metagenomics reveals massive hidden diversity and function in city soils

bigdatabiology.substack.com/p/bdb-lab-ma...

We are preparing the new edition this week, so it's a good time to look back at the past editions

GitHub - BigDataBiology/GMSC-mapper Contribute to BigDataBiology/GMSC-mapper development by creating an account on GitHub.

We released GMSC-mapper v0.2.0! GMSC-mapper queries the Global Microbial smORFs Catalog to find and annotate small proteins from metagenomic data

github.com/BigDataBiolo...

Jug 2.5.0 is out! Jug is a Python framework for parallel & reproducible computation. Write plain Python, run it across many processes or machines with no message-passing code.

pip install jug --upgrade

(Or use the conda-forge packages with conda/pixi)