While this is Round 62, it may be listed as Round 64 on the EBI CAPRI page; we are investigating if this can be changed. (it not, then this will be Round 64)

We are happy to announce CAPRI Round 62, featuring a total of nine antigen/antibody targets.

Registration opens tomorrow, Jan 23rd.

The targets will be offered in two prediction periods, with prediction of the first five targets starting Feb 16th, and of the last four targets starting Mar 16th.

A new CAPRI round is coming up with 4 antibody-antigen targets! The registration opens next Monday (Sept. 22nd). Check it out at www.ebi.ac.uk/pdbe/complex...

Navigating the Pre- and Post-AlphaFold Divide: CAPRI 8th evaluation meeting, February 12-14, Grenoble, FR Navigating the Pre- and Post-AlphaFold Divide: CAPRI 8th evaluation meeting, February 12-14, Grenoble, FRAlexandre M.J.J. Bonvin1 and M. F. Lensink21 Bijvoet Centre for Biomolecular Research, Faculty ...

Navigating the pre- and post-AlphaFold divide: CAPRI 8th evaluation meeting

www.authorea.com/users/348903...

We are happy to announce CAPRI Round 60, with one target: an antibody-peptide complex.

Registration is open.
Prediction starts June 9th.

www.ebi.ac.uk/pdbe/complex...

After a busy CASP/CAPRI year we resume our rolling CAPRI rounds, announcing the 1st target of 2025.

It consists of an antibody-glycan complex. The glycan is heptyl α-D-mannopyranoside.

Registration for this target is now open.

pdbe.org/capri

Early December, the CASP16 Meeting was held in the Palladium resort in Punta Cana, Dominican Republic. Nick Grishin, myself, and Qian Qong presented the assessment of the monomeric structure predictions, the assembly predictions and of monomers in their oligomeric context. 1/n

CAPRI conclusions from the CASP16 assembly session

CAPRI conclusions from the CASP16 assembly session

Improvement in performance with availability of MassiveFold data. Round 58 (CASP stage2 vs stage1)

CASP16 CAPRI ranking on relative model quality

CAPRI ranking on relative model quality (highlighting predictors that do well on the more difficult targets)

CASP16 CAPRI ranking on absolute model quality

The CAPRI ranking on absolute model quality for CAPRI Round 57 (CASP16 session)

And the main conclusions for this years multimer predictions

CASP16 Critical Assessment of Structure Prediction Get tickets on Humanitix - CASP16 Critical Assessment of Structure Prediction hosted by Critical Assessment of Structure Prediction. Grand Palladium Resort, Avenida Francia, Higüey 23000, Dominican Re...

events.humanitix.com/casp16-criti...

How much has the protein assembly modeling field progressed the past two years?

At the CASP16 conference in Punta Cana early December we will present the results of the CASP/CAPRI joint blind prediction round: Round 57 (normal), Round 58 (with MassiveFold data) and Scoring (also with MassiveFold)

MassiveFold: unveiling AlphaFold’s hidden potential with optimized and parallelized massive sampling - Nature Computational Science Although AlphaFold is very efficient for protein structure prediction, massive sampling is a very GPU demanding task. MassiveFold overcomes this limitation, being capable of parallelizing structure pr...

MassiveFold: unveiling AlphaFold’s hidden potential with optimized and parallelized massive sampling.

Out now.

www.nature.com/articles/s43...

CASP16 / CAPRI Round 57 has started.

The first target was released today.

CAPRI-Q: The CAPRI resource evaluating the quality of predicted structures of protein complexes Protein interactions are essential for cellular processes. In recent years there has been significant progress in computational prediction of 3D struc…

www.sciencedirect.com/science/arti...

Joint Integrative Computational Biology workshop and CAPRI Meeting Integrative Computational Biology workshop and 8th CAPRI assessment meeting:Integrative Computational Biology workshopfrom Mo. February 12 at 13:30 to Wed. February 14 at 12:30The first part of the w...

workshops.ill.fr/event/392/

Impact of AlphaFold on structure prediction of protein complexes: The CASP15-CAPRI experiment

doi.org/10.1002/prot...

Welcome to the bluesky presence of the community-wide CAPRI protein docking and assembly modeling experiment.

Please note the 8th CAPRI assessment meeting will be held Feb 12-16 in Grenoble, France, back-to-back with the Integrative Computational Biology meeting. Details to follow.