and finally... Amardeep recently put together an excellent review on non-native B12 enzyme catalysis.

10.26434/chemrxiv-2025-sv6l4

Payal finished off a study of conformational changes relevant to metal-dependent modulation of prolyl oligopeptidase activity by genetically encoded BpyAla residues. Our final effort from a MURI in collaboration with Benoit Roux.

10.26434/chemrxiv-2025-61n8b

Xuzhong recently reported the first example of enantioselective C-C bond formation by a flavin dependent halogenase via halogenative semi-pinacol rearrangement. Very cool…

10.26434/chemrxiv-2025-fdcwp

We contributed some engineered flavin dependent halogenases to a study by the Sherman group that were used for selective modification of the Antimalarial Premarineosin A:

www.nature.com/articles/s42...

Selective Phosphorylation of Phenols and Benzenediols by the Kinase PsiK and Variants Thereof PsiK from Psilocybe cubensis phosphorylates a diverse set of substituted phenols and benzenediols beyond its native substrate. High-throughput screening of active site mutant libraries using DESI-MS ...

Way behind on promoting work from folks in the group… not sure I ever plugged Autumn’s work on selective phosphorylation of small molecule substrates with the kinase PsiK. Great collaboration with Graham Cooks’ group at Purdue and Ryan Phelan at AbbVie:

onlinelibrary.wiley.com/doi/10.1002/...

very sorry to hear this… such a great legacy in his music.

Opinion | Christianity Is a Dangerous Faith

so close, yet so, so far away. an edit striking a few unnecessary details:

But life properly lived is dangerous. It’s dangerous to people who refuse to hate those they are told to hate, to people who refuse to oppress, to conquer, to exploit.

www.nytimes.com/2025/12/21/o...

had to buy one of those little guys when my fam was there last summer. shop owner showed me a list of common symbols in tanuki statues

i still enjoy watching music videos

Silicon Valley is Wrong about Federal University Funding Modern universities are more like a national research labs than colleges. Killing them would handicap America for generations.

Excellent article on the importance of US academic research for US private enterprise, and in particular for Silicon Valley.
open.substack.com/pub/theahura...

Accessibility Update Learn more about the features and functions provided by the NERV Disaster Prevention app.

downloaded for the name, but it is quite good!

nerv.app/en/about.html

i have felt this way since grad school. at this point i don’t even pay attention to them.

Chinese Students Flocked to Central Illinois. Their Food Followed.

america is already great folks www.nytimes.com/2025/07/14/d...

i NEEDED an overpriced 808 tshirt!

fam has had an awesome start to our visit to japan, this pic was preceded by a great time in harajuku before the rain, and i had no clue there was a roland store here, apparently the only one in japan, but the rain was the perfect setting for finding that the store was… closed on tuesdays! so close!

Frame of preference A story of early Mac settings told by 10 emulators.

This is utterly brilliant - Macintosh System Software 1.0, all the way to Mac OS X 10.3 Panther, all with emulations of the software that actually work!! Incredible.

aresluna.org/frame-of-pre...

still hilarious and all too accurate every time

it appears that one of the trial locations is just a couple blocks from the hotel my family and i will stay at in shinjuku later this week. daughters will go crazy over this. thanks!

any record stores that cannot be missed in tokyo, nagoya, kyoto, or osaka?

she was originally a so-cal girl. here she is back in pasadena in 2008.

had to say goodbye to Panda today. seventeen great years with this crazy border collie.

arnold group alums out in force at tom ward’s repartzymes (repurposed and artificial metalloenzymes) conference. great science and awesome community!

Exciting news from the IU Biology Greenhouse!

Wally, our corpse flower (Amorphophallus titanum), is officially preparing to bloom! 🪴🌸

🎥You can watch the livestream: go.iu.edu/8tM8

📷: Jessica L. Hooten, Department of Biology

publican and smart bar are two of my favorite places in chicago. this bathroom in basel looks like the child of their bathrooms’ pagan union.

have to give them a pass on this…

i was initially put off by alchemist in basel because the glassware was not properly assembled, but i found out i could order absinthe feuerzangenbowle-style. and that you get forceps and a mortar/pestle at table… also the food was excellent. shared pak choi, spätzli, lamb shank, and pork belly.

having a great time in basel. plattfon record store is a strong recommend.

wording makes it sound like this could affect grad students also, but i didn’t read the bill text…

that could have gone on for an hour or so…

ICBIC 2025, Long Beach California Join the prestigious International Conference on Biological Inorganic Chemistry (ICBIC) in Long Beach, California in 2025. Discover the latest advancements in the field of biological inorganic chemist...

The International Conference on Biological Inorganic Chemistry (ICBIC) is taking place in Long Beach, CA from July 28 - Aug 1! There is still time to register and submit an abstract! www.icbic21.org