It was a blast to speak today at @leicamicrosystems.bsky.social launch event of the new SCAPE system! As a light-sheet fan, can't wait to see the cool applications the system will have.

EMBL Barcelona has so much to learn

#czechcellence on tap

A stride towards a better liver model By altering the growth environment, the Huch lab at MPI-CBG has developed a liver model that extensively mimics the heterogeneity of the real organ.

By altering the growth environment, the group of @merihuchlab.bsky.social @mpi-cbg.de with first authors Javier Bregante & Flaminia Kaluthantrige has developed a liver model that extensively mimics the heterogeneity of the real organ. @cp-cellreports.bsky.social. www.mpi-cbg.de/news-outreac...

Empowering the next generation of bioimaging experts! 🌎

After many months crafting the Lightsheet Image Analysis Workshop 2026 with @bruvellu.bsky.social & @cuencam15.bsky.social. Seeing students finally crack their toughest project data on day 5 made every hour of prep worth it! 🧵👇

Happy to present for the first time my postdoc project, characterizing airway organoid architecture at the EMBO organoid conference #EESOrgan Stop by on Friday on poster #80!
@events.embl.org

The Secret to a Smooth Pasta Sauce Wins Ig Nobel Prize Italian researchers studied how the ingredients of the traditional Roman dish cacio e pepe emulsify into a creamy sauce, winning the 2025 Physics Ig Nobel Prize.

Truly chuffed for our fearless food physicists @mpipks.bsky.social + collabs from AT @istaresearch.bsky.social, IT & ES who won this year’s Ig Nobel - the #NobelPrize of hearts❤️for cracking the science of perfect pasta !🍝Kudos to all for intrepidly consuming lots of cheese in the name of science!😋

Congrats Ryan!! Looks amazing ✨

(1/14) I’m happy and proud to introduce: SpinePy – a framework to detect the "spine" of gastruloids and measure biological and physical signals in a local dynamic 3D coordinate system. www.biorxiv.org/content/10.1...

So happy to see the cephalic furrow combo out back-to-back! This was a wonderful collaborative endeavor 🥹

Super congrats!!!

Flies evolved a shock-absorber tissue used during embryonic development The role of tissue that forms between the head and trunk of a fly embryo has been unclear. It turns out that it absorbs forces when nearby cells move and divide.

Thanks to Mary Abraham for editorial help with the N&V and huge thanks to @levayerr.bsky.social for proofreading/fact-checking it. Fly development can be a bit far from my comfort zone, so it’s always reassuring to have an expert in your corner. www.nature.com/articles/d41...

Some of the work behind this paper. Honoured to be part of it!
Special thanks to @paveltomancak.bsky.social for giving me a space in his lab at @mpi-cbg.de and to @bruvellu.bsky.social for being such an inspiring scientist.

Mechanical forces drive evolutionary change A small tissue fold present in fruit fly embryos buffers mechanical stresses and may have evolved in response to mechanical forces.

Dresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social ‬ & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...

Wow! I just learnt about annual killifish development and was amazed!

Great opportunity at EMBL HD!

Day 11 of #LISH25
Not everyone in the pic but wanted to give a big shout out to the stars of the course. The amazing students that survived us and went home with amazing data!

@olafselchow.bsky.social
@olafselchow.bsky.social
@bundschuhst.bsky.social
@paveltomancak.bsky.social

Super happy and honoured to have been able to share once with these guys in love with microscopy #LISH25

Dresden will always feel like home.

@ereynaud.bsky.social
@mpi-cbg.de
@paveltomancak.bsky.social
@olafselchow.bsky.social
@bundschuhst.bsky.social

#LISH25 final student team presentations. #The_Holy_de_Broglies

#LISH25 final student team presentations. #Liv_and_Dye

Thank you @paveltomancak.bsky.social @olafselchow.bsky.social @dvonwangenheim.bsky.social @bundschuhst.bsky.social @ereynaud.bsky.social @cuencam15.bsky.social Vlado, Stephan for a life-changing lightsheet experience towards even more beautiful and high-quality science

#LISH25 final student team presentations. #Specimen_Illuminati

... and @dvonwangenheim.bsky.social's great video montage of a few of the samples. #LISH25
🔬🌍: www.intelligent-imaging.com/AxL

Walking into the brain of an Alzheimer’s mouse. I overloaded the mouse with therapeutics (pink) and labeled vessels (green), and was clearing the brain for almost 2 months. Thanks to Stephan for a nice movie from #Blaze microscope at #LISH25 #LISH2025

Day 11 of #LISH25
Last lectures of the course, closing with beautiful plant light sheet imaging by Maria Cuacos and organoids by Gustavo Madeiros.

From now on, data transfer, analysis and presentation preparation!

@paveltomancak.bsky.social
@bundschuhst.bsky.social
@mpi-cbg.de

Day 10 of #LISH25
Late night image analysis as the end approaches.
Tired but still going on!

@paveltomancak.bsky.social
@mpi-cbg.de
@bundschuhst.bsky.social
@events.embl.org

Day 9 of #LISH25
Some field trip to haunt for tasty specimens

@paveltomancak.bsky.social
@bundschuhst.bsky.social

Day 8 of #LISH25
Instructors also are getting their hands dirty, but looking cool

@paveltomancak.bsky.social
@bundschuhst.bsky.social
@mpi-cbg.de

Light sheet close up

Day 7 of #LISH25
After a well deserved day off we came back BIG.
Mesoscopic light sheet imaging of lost and found specimens in the wild. Caught by @giuliaserafini.bsky.social

@mpi-cbg.de
@whyvinca.bsky.social
@paveltomancak.bsky.social
@bundschuhst.bsky.social

We miss u @ereynaud.bsky.social

Bye bye #lish25... Time to cry for 12 hours in trains... Will miss you all even @paveltomancak.bsky.social Keep up the good work!
@bundschuhst.bsky.social @cuencam15.bsky.social