Leopard-EM: an extensible 2D template-matching package to accelerate in situ structural biology In situ cryo-EM coupled with 2D template matching (2DTM) holds the potential to visualize the cellular structureome in context, but further developments are required to make this a reality. We describ...

Now out in full form. Again, a big thanks to #teamtomo and @alisterburt.bsky.social for developing the infrastructure to build this on. journals.iucr.org/d/issues/202...

CZII - CryoET Object Identification Find small biological structures in large 3D volumes

For the #ML and #CryoET folks out there:

Are folks on here submitting to the CZII CryoET Object Identification competition: www.kaggle.com/competitions... ?

The leaderboard is really interesting, and the forums are full of insights.

How many of the latest picking models have been submitted?

Hi Bluesky folks! I’m a Computational Biology PhD student at the Lucas Lab, UC Berkeley. I’m currently working on designing ML algorithms to find macromolecules within cryo-EM images of crowded cell environments! Excited to connect with likeminded people here!