On the newest episode of #GenomicsFutures, we discuss if the term “global health” is as global as we think, how certain aspects of life can erode the microbiome, and the opportunities and limitations for ‘digital twins’. 🦠
Listen here ⤵️
www.sanger.ac.uk/innovation/o...
Read 'Genomic evolution and natural history of myeloproliferative neoplasms on therapy' by @sangerinstitute.bsky.social and @cuh.nhs.uk in @aacrjournals.bsky.social here ⤵️
aacrjournals.org/cancerdiscov...
Uncovering patterns in DNA could help improve diagnosis, monitoring and treatment of rare blood cancers. 🩸
A new decades-long study has revealed why some patients' blood cancer remains stable while others worsen and even suggests some patients may be misdiagnosed.
www.sanger.ac.uk/news_item/de...
Dr Ayesha Noorani, a member of @crukcamthoracic.bsky.social and @cancerresearchuk.org-funded Clinician Scientist at the @sangerinstitute.bsky.social and @cuh.nhs.uk, has been named a rising star shaping the future of cancer research!
🔗 www.nature.com/articles/d41...
Sequencing all complex life in the UK & Ireland could add up to £3bn to the economy over 30 years, a new report finds.
Explore the impact of the Darwin Tree of Life Project ⤵️
www.sanger.ac.uk/news_item/unlocking-the-...
2/ Their thoughts have been captured in a new report and a limited podcast series, with the first episode now live.
Find out more here: www.sanger.ac.uk/innovation/sanger-genomi...
What will genomics look like in 2050? 🤔
25 years on from the first draft of the human genome, the Genomics Futures workshops brought together experts from across the world to talk about what the future could bring.
Read 'Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity’ by @sangerinstitute.bsky.social and collaborators in @nature.com ⤵️
www.nature.com/articles/s41...
Autoimmune diseases may be driven by DNA changes that build up over time in our immune cells. 🧬
New research has identified previously unseen DNA changes that may contribute to thyroid autoimmunity, where the immune system attacks the thyroid gland. 👇
www.sanger.ac.uk/news_item/hi...
Scientists have loaded a complete virus genome onto a quantum computer for the first time. 🚀
This is a huge step towards transforming genomics and may lead to faster disease tracking or unlocking rare genetic insights.
Read the full story 👇
https://bit.ly/4mma5pJ
Scientist wearing gloves analyses a tissue sample on a Xenium spatial machine.
How did spatial transcriptomics become a cornerstone of modern biology? 🔎🧬
Explore the journey at the Sanger Institute – from early methods to today’s high-resolution maps of gene activity in tissues.
sangerinstitute.blog/2026/04/09/the-history-o...
Read 'Evolution of Pandemic Cholera at its Global Source’ from @sangerinstitute.bsky.social, @amberbarton.bsky.social, icddr,b, PGIMER, and others in @nature.com, here ⤵️
www.nature.com/articles/s41...
Cholera-causing bacteria are locked in an evolutionary arms race with their viral nemesis found in the human gut, according to a new study. 🦠
Find the full story here ⤵️
www.sanger.ac.uk/news_item/on...
James McCulloch out in the woods doing fieldwork, sampling for invertebrates.
Meet @jamesimcc.bsky.socialy.social, the UK's national recorder for springtails and a PhD student here at the Sanger Institute.
James merges taxonomy expertise with genomics for a deep-dive into springtail DNA.
Learn more ⤵️
sangerinstitute.blog/2026/03/26/studying-soil...
If you want to find out more about Jukka Corander, senior author, check out this recent blog article diving into his work, and how his passion has shaped his career 👉 sangerinstitute.blog/2026/02/24/i...
Read ‘Identification of transporter-dependent capsular K loci associated with invasive potential of Escherichia coli’ from @sangerinstitute.bsky.social, University of Oslo, and others in @natmicrobiol.nature.com
www.nature.com/articles/s41...
The first large-scale genetic study of E. coli’s protective armour has found 5 capsule types that account for 70% of multidrug-resistant bloodstream infections in Europe.
Creating a blueprint of E. coli’s armour can help design new ways to tackle the strains that cause infections.
bit.ly/41wdOY4
Microscopic view of Haemonchus contortus, also known as barber’s pole worm.
Parasitic worms might not be cute, but they are fascinating.
From global health impacts to cutting-edge genomics, we explore why helminths matter more than you think.
Read more 👉 sangerinstitute.blog/2026/03/17/what-the-hel-...
A genomic blueprint has been created for Aeromonas, a type of bacteria which can cause antibiotic-resistant diarrheal disease, with symptoms often misidentified as cholera.
This could help develop a rapid test in the future. Find out more ⤵️
www.sanger.ac.uk/news_item/un...
Why does sepsis affect people so differently? Scientists are using genomics to identify distinct immune response patterns that could help identify and treat sepsis early.
Learn more 👉 sangerinstitute.blog/2026/03/10/decoding-seps...
Dr Jyoti Nangalia stands smiling at the camera. Jyoti is wearing a purple academic gown and is standing next to a member of the Royal College of Physicians who is wearing a gold and black academic gown, and and she is handing the Fellowship to Jyoti. Others are sat in the background in front of book cases.
Congratulations to Jyoti Nangalia on being appointed a Fellow at the @rcphysicians.bsky.social 🙌
The Fellowship recognises Jyoti's unwavering commitment to cancer genomics, clinical practice and improving outcomes for patients.
Read more ⤵️
https://bit.ly/4rjDzFv
Text card that reads: The understanding that we live whole lives, and the support given for things that happen outside of work. “I lost my husband 2 years ago and was dreading coming into the office. I was overwhelmed with the support, encouragement and care that I received from my colleagues. Their gestures of taking me for a coffee and a chat or for lunch helped me get through each day then, and still does now. The support from my colleagues had a large impact on my career and has helped me through the past 2 years for which I am really grateful.” Julie McKeown, Personal Assistant
Text card that reads: Having supportive colleagues who help give you the confidence to apply for new opportunities. “When I was considering changing from a lab-based role to one in Research Governance, I had a few doubts, but my colleagues were really encouraging. I have heard that women are less likely than men to apply for a job if they don’t have all the requirements listed. Instead of not applying, I reached out to the hiring manager to find out more, and I am happy to say I’ve now been in the role for 3.5 years. This support from friends, colleagues, and my future employer may have been small, but together they really helped support my decision to pursue my biggest career change to date.” Jessica Petty, Research Governance Assistant
Text card that reads: My relationship with my mentor. “Since I started working with my mentor, I have hugely developed in my role as a Software Developer and decided to take a secondment into culture work, an entirely new role for me. By developing my skills in the workplace and having a mentor to discuss ideas, strategies, and ambitions with, my confidence and visibility have increased.” Jessica Cox, Equity, Diversity and Inclusion Manager.
Text card that reads: Access to training opportunities that build both technical and leadership skills. “Working at the Wellcome Sanger Institute has enabled me to grow both technically and professionally, through opportunities such as the Herschel Programme for Women in Technical Leadership and the Technical Commitment Network. The combination of technical development and leadership training has strengthened my confidence, expanded my skills, and allowed me to support others as they step into genomics.” Vaishnavi Gangadhar, Informatics Technical Officer
Read more of the responses ⤵️
Text card that reads: “International Women’s Day 2026. What has been the most impactful support you have received in your career?” on a purple background.
Text card that reads: Learning and growing through mentorship. “The most transformative support I have received thus far in my career has been mentorship through the NIHR Mentoring Programme. I was incredibly fortunate to have been assigned an empowering woman mentor and leader who validated my challenges and equipped me with the self-assurance to navigate them. I entered the mentoring relationship as an underconfident employee and emerged as a determined scientist with a pioneering mindset.” Britt Hanson, Postdoctoral Fellow. *NIHR is the National Institute for Health and Care Research
Text card that reads: Being a part of a community that recognises and uplifts everyone. “What has been a constant impact on my career is having people around me who genuinely uplift and support one another. When someone takes the time to recognise your strengths, it builds confidence and reminds you what you’re capable of. Being part of that kind of supportive community pushes me to keep growing, to be present and to attempt to give my best every day.” Anna Milizia, Team Administrator
Text card that reads: Having managers who encourage me to explore new opportunities. “One example is Dr Henrique Girão, my supervisor during my first job in science. From the beginning of this role, I asked to be involved in activities that were outside my job description. With Dr Girão’s support, I attended lab meetings to engage in scientific discussions, assist with more complex experiments, and earn additional certifications. His encouragement helped shape my development and was one of the first steps that eventually led me from Portugal to the Wellcome Sanger Institute.” Diana Adão, Advanced Research Assistant
Ahead of International Women’s Day, we asked our colleagues to share what has helped them in their careers.
Scroll through to see what they said ⤵️
Congratulations to Iñigo Martincorena and Omer Bayraktar, who have both received a @cancergrand.bsky.social award 🎉
Read more about their projects ⤵️
www.sanger.ac.uk/news_item/sanger-scienti...
Alice Mann stands next to a quote about AI's importance in genomics research. The quote reads: "AI plays a critical role in understanding and solving complex problems in genomics, and this initiative will provide financial and mentoring resources to empower the fellow as they pursue their own independent research."
We’re excited to announce a new Google DeepMind Fellowship, hosted at the Wellcome Sanger Institute. 📣
The fully funded Fellow will be mentored by Google DeepMind researchers and AI experts.
Read more about the opportunity here 👇
https://bit.ly/4bl3ckx
Yvette wearing a blue lab coat and green gloves smiles while working with lab equipment at a workstation in a bright laboratory.
Meet Yvette Hooks, Senior Technical Specialist in histology. She is the expert behind the scenes, making the invisible visible – one ultra-thin slice at a time.
Read Yvette’s story 👇
sangerinstitute.blog/2026/03/03/slicing-and-d...
Now online! In this review, we cover four major topics on butterflies and moths: their evolutionary history and diversification dynamics, genomics, global diversity patterns, and conservation 🦋🌏 (1/8) @natrevbiodiv.nature.com
www.nature.com/articles/s44...
What stories can DNA tell us about how animals have survived in the face of a changing environment? 🧬 Listen to the latest episode of the #ZSLWildScience podcast to learn more: open.spotify.com/episode/6VXY... @sangerinstitute.bsky.social
Ahead of Rare Disease Day, we are resharing our blog with Professor Matt Hurles on the power of genomics to accelerate rare disease diagnosis and research.
Check it out 👉 sangerinstitute.blog/2025/02/28/five-question...
Jukka in a red beanie and glasses smiling outdoors in a misty forest, wearing a black jacket, with hand raised holding a berry.
What do games, pies, raves & bacterial evolution have in common? Jukka Corander.
From stats to genomics — read his journey👇
sangerinstitute.blog/2026/02/24/i-am-reborn-a...