Nav1.8 Variant I206M as a Latent Susceptibility Factor in Postaxotomy Ocular Pain | Neurology Genetics Background and ObjectivesA small proportion of patients develop persistent ocular pain after corneal refractive surgery, which injures the distal axons of trigeminal ganglia neurons innervating the ey...

Our new paper is out in Neurology Genetics: Nav1.8 Variant I206M as a Latent Susceptibility Factor in Postaxotomy Ocular Pain. www.neurology.org/doi/10.1212/...

Matching sodium channel availability to resting membrane potential: Biophysical logic across excitable cell types Abstract figure legend Matching sodium channel availability to resting membrane potential defines excitable cell function. Top, schematic summary illustrating how the relative alignment between Nav c...

Excited to share our new paper in @jphysiol.bsky.social: Matching sodium channel availability to resting membrane potential: Biophysical logic across excitable cell types.

physoc.onlinelibrary.wiley.com/doi/10.1113/...

High-throughput multiplex voltage-clamp/current-clamp evaluation of acutely isolated neurons Nature Protocols, Published online: 13 June 2025; doi:10.1038/s41596-025-01194-0This Protocol describes an automated high-throughput patch-clamp approach that enables the simultaneous and unbiased analysis of acutely dissociated neurons in their native state, with diverse applications ranging from the assessment of neuronal biophysics to drug development.

New Article! High-throughput multiplex voltage-clamp/current-clamp evaluation of acutely isolated neurons

Frontiers | Brain stimulation enhances dispositional mindfulness in PTSD: an exploratory sham-controlled rTMS trial

Pleased to share this new paper: www.frontiersin.org/journals/psy...

In Vitro Inhibition of Voltage-Dependent Sodium Currents by the Antifungal Drug Amorolfine Voltage-gated sodium (Nav) channels are critical for electrical signaling, and their pharmacological modulation can be leveraged for the development o…

Pleased to share our new paper: www.sciencedirect.com/science/arti...

Targeted ubiquitination of NaV1.8 reduces sensory neuronal excitability Chronic pain and addiction are a significant global health challenge. Voltage-gated sodium channel NaV1.8, a pivotal driver of pain signaling, is a clinically validated target for the development of n...

Our new study: Targeted #ubiquitination of #NaV1.8 reduces sensory neuronal excitability. #pain @yale.edu
www.biorxiv.org/content/10.1...

Endocannabinoid contributions to the perception of socially relevant, affective touch in humans - Neuropsychopharmacology Neuropsychopharmacology - Endocannabinoid contributions to the perception of socially relevant, affective touch in humans

The first @pact-lab.bsky.social paper of 2025 is out now in @npp-journal.bsky.social 🤩

Led by @madeleinejones.bsky.social & @connorhaggarty.bsky.social
ft. @abby-lunge.bsky.social @cannabrain.bsky.social & others

www.nature.com/articles/s41...

BOOM! Big advance in our understanding of the pharmacology of CBD, CBN, and most importantly CBG. New work from the Waxman lab showing these "minor" cannabinoids act on Nav1.8: www.pnas.org/doi/10.1073/...