Multiple modes of cholesterol translocation in the human Smoothened receptor Multiple competing hypotheses concerning the cholesterol accessibility of oncoprotein Smoothened are quantitatively assessed and experimentally validated, showing that cholesterol takes two pathways from...

Multiple modes of cholesterol translocation in the human Smoothened receptor

https://www.biorxiv.org/content/10.1101/2025.08.20.671365v1.full.pdf

1/ 🔬 Thrilled to share our new preprint: ESMDynamic: Fast and Accurate Prediction of Protein Dynamic Contact Maps from Single Sequences
📄 Now on bioRxiv: t.co/xVxDf2zm3M

Congratulations to the newest doctor from our group Dr. Xuenan Mi!