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Posts by Stelios Tsagkris

I wonder if we would have mRNA therapeutics if Karikó had taken similar advice.

3 months ago 4 1 2 0
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🗨️ Just published in Nature Biotechnology: Our CellWhisperer AI enables chat-based analysis of single-cell sequencing data. You can talk to your cells & figure out the biology without writing any computer code. Paper here: www.nature.com/articles/s41.... Annotated walkthrough in a thread below (1/11)

5 months ago 64 36 2 2
Fabio Petroni, group leader at EMBL Rome. Credit: Eugenio Battaglini

Fabio Petroni, group leader at EMBL Rome. Credit: Eugenio Battaglini

After many years abroad, Fabio Petroni has returned to Italy to establish an independent research group at EMBL Rome.

Here, he will be developing AI systems to support life science research.
Read more in his interview: www.embl.org/news/?p=7718...

5 months ago 1 1 0 0
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We are looking to take on an intern at EMBL Rome, for anyone interested in CRISPR and Epigenetics training.

The traineeship is 3-12-months, in Rome (Italy), should start by July, and is supervised by the outstanding @steliostsagkris.bsky.social.

#job #internship; see info below...

11 months ago 19 15 2 0

I think people both within science and outside science don’t fully appreciate the miracle that were the Covid-19 vaccines. How much courage it took to get the sequence out, how much work had already gone into figuring out the best viral antigen and how best to present it. 1/

1 year ago 769 188 9 12
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Do you have ambitious plans to study the molecular mechanisms of environmental adaptation in mammalian model systems? Join EMBL Rome as an independent group leader: generous core funding & benefits, top-level students & core facilities. embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

1 year ago 6 7 0 0
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Paternal microbiome perturbations impact offspring fitness Nature - Disturbances in the gut microbiota of male mice manifest as fitness defects in their offspring by affecting plancenta function, revealing a paternal gut–germline axis.

As an "EIPOD" interdisciplinary postdoc in @jamiehackett.bsky.social and our lab, @denbobalab.bsky.social found that "Paternal microbiome perturbations impact offspring fitness" (2024): antibiotic treatment of male mice led to low birth weight & higher mortality in offspring

www.nature.com/artic...

1 year ago 15 6 1 1
Advert detailing a postdoctoral scientist position at EMBL Rome. Contact: jamie.hackett@embl.it

Advert detailing a postdoctoral scientist position at EMBL Rome. Contact: jamie.hackett@embl.it

Postdoc positions in epigenetics!

We have several opportunities to investigate big picture questions on (epi)genome function & mechanisms

Based @embl.org near Rome (Italy), we offer full scientific support/facilities, training & funding. Also...☀️🏛️🍕🏖️

See👇or contact me for other options. Pls RS

1 year ago 81 56 0 10

My first post - Blue sky in Orbetello, Italy

1 year ago 4 0 1 0
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Evo, a 7-billion-parameter genomic foundation model, learns biological complexity from individual nucleotides to whole genomes.

Evo, a 7-billion-parameter genomic foundation model, learns biological complexity from individual nucleotides to whole genomes.

Pretraining a genomic foundation model across prokaryotic life.

Pretraining a genomic foundation model across prokaryotic life.

Fine-tuning on CRISPR-Cas sequences enables generative design of protein-RNA complexes.

Fine-tuning on CRISPR-Cas sequences enables generative design of protein-RNA complexes.

Fig. 4. Fine-tuning on IS200/IS605 sequences enables generative design of transposable biological systems.

Fig. 4. Fine-tuning on IS200/IS605 sequences enables generative design of transposable biological systems.

Evo: A genomic language model of prokaryote genomes generates functional cas9 proteins and transposons.

@brianhiestand.bsky.social

www.science.org/doi/10.1126/...

1 year ago 59 27 0 1