Finishing up in snowy Banff with current and former Broz Lab members after the innate immunity symposium. @jakubbegan.bsky.social @kaiwenchen-lab.bsky.social @ehartenian.bsky.social @keystonesymposia.bsky.social

Thanks a lot🙌

Caspase-4 binds to LPS membranes with positive curvature for non-canonical inflammasome activation | Jakub Began I am excited to share that our study describing the molecular mechanism of caspase-4 activation has just been published in Immunity. https://lnkd.in/e68uHHAA I would like to thank all the co-authors...

www.linkedin.com/posts/jakub-...

Caspase-4 binds to LPS membranes with positive curvature for non-canonical inflammasome activation The cytosolic LPS sensor caspase-4 controls antibacterial immunity by inducing pyroptosis and cytokine secretion. Began et al. show how remodeling of LPS membranes by interferon-induced GTPase GBP1 pr...

PAPER ALERT!
I am excited to share that our study describing the molecular mechanism of caspase-4 activation has just been published in Immunity.
www.cell.com/immunity/ful...

I would like to thank all the co-authors for their valuable contributions.
Well done guys!
Link for short summary below👇