How artificial intelligence is reengineering protein engineering Over the past decades, protein engineering has matured into a field of its own, driven by computational modeling and high-throughput wet lab experiments, with broad application in therapeutics, diagnostics, agriculture, and manufacturing. In recent years,...

Our review on AI for protein engineering is out now, about this too-fast-moving field full of hype and overclaim, yet one that is having a real impact on the world and can be described in a coherent manner without histrionics. www.science.org/eprint/666XR...

ICLR Poster Unlocking Guidance for Discrete State-Space Diffusion and Flow ModelsICLR 2025

Hunter Nisonoff and Junhao Xiong are at ICLR presenting their poster on how to correctly do guidance for diffusion and FM in discrete state spaces, such as for protein engineering (joint w Stephan Allenspach). Go chat with them! iclr.cc/virtual/2025...