Preprint: Multi-omics definition of the sex-specific glycoproteome of murine tissues - IonOpticks Kawahara et al.'s preprint on the sex-specific glycoproteome of murine tissues used an Aurora Ultimate 25×75 UHPLC column.

Kawahara et al. profile the sex-specific N-glycoproteome across 19 mouse tissues using TMT-based quantitative glycoproteomics. 26,800+ glycoforms quantified across ~1,500 glycoproteins using Aurora Ultimate 25x75 column + Vanquish Neo + Orbitrap Exploris 240.

Learn more: bit.ly/4so1FzJ

IonOpticks proudly supports YPIC’s networking event at the Annual Proteomics Gathering on April 16. Join the ECR community to celebrate shared progress + connect in a relaxed setting at The Beer Temple in Madrid.

Register via the Google Form link by Thursday April 9.

@eupaproteomics.bsky.social

NOW PUBLISHED: Lowering FAIMS resolution on the Orbitrap Astral increases peptide identifications by 6-18% across sample loads from 250 pg to 16 ng, as demonstrated in new research from the Mechtler lab using Aurora Rapid 8×75 XT columns: bit.ly/4s0GELj
@matzingerm.bsky.social
@impvienna.bsky.social

REMINDER: Join Fabrice Odefrey and @mpibiochem.bsky.social's Dr Tim Heymann for the IonOpticks Insights webinar at 9:00am CET / 4:00pm CST.

A recording will be available to everyone who registered, so if you can’t make it, register anyway and watch at your own convenience: bit.ly/416G6Ix

Nuclear speckles enable processing of RNA from GC-rich isochores Nuclear speckles are key subnuclear structures that regulate gene expression in GC-rich regions. This work shows that the evolution and expansion of core speckle proteins were crucial for the increase...

The @aktast.bsky.social lab dismantled nuclear speckles for the first time to probe their role in genome organisation and RNA processing. In global quantitative proteome profiling, peptides were separated on an Evosep One coupled to a timsTOF SCP with Aurora Elite 15x75 CSI columns.
bit.ly/3PTia97

It's great to see Aurora Series columns featured in Heymann et al.'s new BioRxiv preprint in collaboration with SCIEX - and the results speak for themselves. Congrats to all involved on this milestone.

lnkd.in/gv_9Y3Kc

Want to hear more from Dr. Heymann? Register for our webinar: bit.ly/4lPxNe1

IonOpticks proudly supported #MMSDG in Montréal this week. Dr Brendon Seale (LTRI) showcased how Aurora Series® columns enable reproducible, high-throughput proteomics without sacrificing depth, while reducing operational burden & facility overheads. Thanks to MMSDG & Dr Seale for the opportunity.

IonOpticks Certified as a Great Place to Work® - a reflection of its people as the company scales globally. As a globally recognised certification based entirely on independently verified employee feedback, the result is grounded in what employees themselves have said about their experience. The 2026 survey...

IonOpticks, a world-leading manufacturer of liquid chromatography solutions, has today been officially Certified as a Great Place To Work®

Based on an independently verified employee survey, 90% of staff agree, highlighting a strong culture as the company scales globally from its Melbourne origins.

REGISTRATION NOW OPEN: Join @mpibiochem.bsky.social's Dr Tim Heymann and Fabrice Odefrey for the IonOpticks Insights webinar on Thursday, March 26 at 9:00am CET / 4:00pm CST.
Can’t attend live? A recording will be available to registered participants 48 hours post-event.
Register now: bit.ly/4lPxNe1

Generation 4 Aurora Series capillary flow column range - IonOpticks Resolution and speed without compromise Generation 4 Aurora Series® 150 μm capillary flow columns deliver exceptional stability throughout both individual runs and extended research campaigns, maintai...

Powering proteomics at scale: Aurora Series 150 µm columns deliver robust, reliable performance with high sensitivity, deep coverage, and exceptional reproducibility - keeping high-throughput labs running. Explore online: bit.ly/AuroraSeries150

IonOpticks’ Fabrice Odefrey will be in Hong Kong on March 30–31 and has limited availability to meet with local researchers. If your lab is working in proteomics or LC-MS workflows and would like to connect, please contact Fabrice directly via LinkedIn or WeChat to arrange a time during his visit.

Join IonOpticks and Dr Tim Heymann (@mannlab.bsky.social Max Planck Institute) for our webinar on March 27, combining advanced MS with optimised separations. Learn how workflows on Orbitrap Astral and ZenoTOF 8600 enable reproducible, high-performance proteomics. Registration opens Friday March 13.

IonOpticks recently visited China to meet researchers & partners across leading labs including Shanghai Jiao Tong University, PiHub, Suzhou Institute of Systems Medicine & Roche Shanghai. With our distributor OmicSolution, the team discussed LC-MS workflows & future collaboration across the region.

Also, as promised, since my #USHUPO2026 poster didn’t have some of my most recent data, @ionopticks.com columns were used in our preprint www.biorxiv.org/content/10.6... & they are my go to column moving forward! Looking forward to trying their new trap column the next opportunity I get.

Brunken et al. investigated the process that drives CIN through mechanisms relevant to early cancer development. Peptides separated on a Vanquish Neo with Aurora Rapid 8x75 XT column. MS performed on an Orbitrap Astral.

Learn more: bit.ly/4d3UuIH

Image from Brunken et al. bioRxiv (2026):

Armed and ready: How Alejandro Brenes is uncovering the hidden lives of neutrophils in brain cancer Dr. Alejandro Brenes, a Wellcome Trust Early Career Fellow at the University of Edinburgh’s Institute for Regeneration and Repair, is uncovering hidden neutrophil populations in glioblastoma that coul...

Single-cell proteomics revealed neutrophil populations in glioblastoma that transcriptomics missed. Some may be blocking blood vessels & worsening outcomes. @ajbrenes.com on the hidden complexity of "soldier cells" & his journey from accidental researcher to Wellcome Trust fellow: bit.ly/46HuIGu

We're proud to support the next Montreal Mass Spectrometry Discussion Group event, including a featured talk by our nominated guest speaker, ‪@brendonseale.bsky.social

Join us Monday, March 17 from 6pm – 8pm at @umontreal.ca Université de Montréal – MIL Campus.

Great knowledge sharing initiative.

Brain and neural cell type proteomics reveal extracellular matrix proteins enriched in progressive multiple sclerosis - Nature Communications The underlying molecular mechanisms of neuroinflammation and axonal damage in progressive multiple sclerosis remains unclear. Here, authors show proteomics results of human progressive multiple sclero...

Wang et al. shed light on the proteomic landscape of PMS, potential implications for biomarker discovery and future therapeutic targeting of neuroinflammatory pathways.
Data acquired on Orbitrap Fusion Lumos + EASY-nLC 1200, peptides separated on Aurora Ultimate 25x75 column.

go.nature.com/46lY3Gd

With day 2 about to kick off, #USHUPO2026 is in full swing. Still building your agenda? With so many excellent poster presentations, here are some that we think are worth checking out today - all in the Regency Ballroom from 4:30pm - 6:30pm.

See the full list: bit.ly/3NZ3IMa

At SCIEX's #USHUPO2026 Seminar, Dr Tim Heymann showed how the ZenoTOF 8600 + Evosep Eno + Aurora XS columns deliver robust, high-quality data across single-cell, global & targeted proteomics, without rebuilding workflows. Up to 4,700 proteins from a single cell with low CVs using 1400ms ZT Scan DIA.

Day 1 of #USHUPO2026 is underway with strong interest in our Nanoshield™ trap columns and Aurora 150 µm analytical range for robust, high-throughput workflows. Dr. TJ Blackburn’s trap comparison poster engaged valuable discussion. Visit Booth 7 to meet our team and discuss your separations needs.

Join SCIEX’s #USHUPO2026 lunch seminar to hear Tim Heymann present how pairing the ZenoTOF 8600 with Aurora XS columns delivers high-sensitivity, stable, and reproducible proteomics workflows, powering applications from single-cell analysis to large-scale discovery studies.

Are you at #USHUPO2026? Catch Dr. TJ Blackburn's lightning talk from 3:15pm to 4:30pm (Grand DE).

Can’t make it? TJ will also share this work as a poster presentation P10.03 in the Regency Ballroom from 4:30pm - 6:30pm.

Learn about our full scientific presence at US HUPO: bit.ly/3NZ3IMa

Beyond the ‘wizard in the basement’: How Luke Gamon is simplifying spatial proteomics for clinical discovery Assistant Professor Luke Gamon, at the University of Copenhagen, is rethinking how we study heart disease by zooming in on the microscopic battles that occur within atherosclerotic plaques. Throughout...

"If you know your sample well, you can do meaningful spatial proteomics with just your hands and a microscope, basically." @lgamon.bsky.social is proving that breakthrough science doesn't always need expensive automation. Read about his accessible approach to heart disease research: bit.ly/3MDkjVc

Not long until #USHUPO2026 - check out Dr. TJ Blackburn’s lightning talk & poster presentation P10.03 on Mon, Feb 23 from 3:15pm. Learn the science behind NanoShield™ trap columns, how they perform in real workflows, and what that means for your robustness and consistency.
Learn more: bit.ly/3NZ3IMa

Today we recognise and celebrate the women of IonOpticks on the UN's International Day of Women & Girls in Science. This year's theme reflects the importance of inclusion, opportunity & progress. Thank you for the talent, care & impact you bring to our team & the scientific community every day.

IonOpticks was proud to attend the @ubuntuproteomix.bsky.social Summer School for 2026. Dr @jsandow.bsky.social presented on chromatography fundamentals, we sponsored three students & provided our popular IO hats for all. Thanks to the organisers for another great event & we look forward to 2027.

Heard the hype about NanoShield™? Join Greta Briedytė at #LorneProteomics poster #105 to see how our new trap column improves sample cleanliness, extends analytical column life, reduces loading time, and delivers near direct-injection performance. Grab the application note at our booth.

After a great day of talks and posters at #LorneProteomics 2026, it was fantastic to host our IonOpticks Peaks and Pints event at the Lorne Hotel. Thanks to the 68 guests who joined us for a relaxed evening of conversation and catching up. Looking forward to another great day ahead.

Poster Spotlight: Emery-Corbin et al, #LorneProteomics poster #34, benchmark plasma proteomics workflows using Aurora® Ultimate™ 25×75 and Elite™ 15×75 columns. Their study shows workflow selection must be cohort-specific, revealing distinct sub-proteomes across clinical and translational settings.