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Posts by Rodrigues Lab

Assistant Professor x6 (111522-0426) - University of Warwick Title: Assistant Professor x6 (111522-0426). Application Deadline: . Position Type: Permanent

My super department @warwicklifesci.bsky.social is hiring 6 assistant profs in the wake of recent retirements. We're looking for people in microbiology/infection, cellular disease / immunity; environmental biology; and plant/crop science. #MicroSky warwick-careers.tal.net/vx/lang-en-G...

1 day ago 48 78 2 0
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Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape Bacteria, like eukaryotes, use conserved cytoskeletal systems for intracellular organization. The plasmid-encoded ParMRC system forms actin-like filaments that segregate low–copy number plasmids. In m...

Out now in @science.org
Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape | Science www.science.org/doi/10.1126/...

4 days ago 62 28 0 1
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Why do intrinsically disordered proteins appear larger than they are in SDS-PAGE? We investigate how sequence properties affect SDS-PAGE mobility using synthetic IDRs.

Conclusion: We need to consider both SDS binding and the compaction of protein-SDS complexes.

www.biorxiv.org/content/10.6...

3 weeks ago 80 24 5 2
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AlphaFold database has entered the era of complexes. Together with NVIDIA, DeepMind and EBI, we use ColabFold, OpenFold and MMseqs2-GPU to predict ~31 million complexes (homo & hetro-dimers) resulting in 1.8 million high-quality predictions
📄 research.nvidia.com/labs/dbr/ass...
🌐 alphafold.ebi.ac.uk

1 month ago 265 111 8 3
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Darwin, in his "The Various Contrivances by which Orchids are Fertilised by Insects", studied the evolution of orchid morphology and its relationship to insects. This is Angraecum sesquipedale, one of the orchids examined in this study. Fragrant at night attracting a moth for pollination.

1 month ago 3 0 0 0

Find the hot-off-the-press plasmids here!
www.addgene.org/browse/artic...

2 months ago 5 3 0 0
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'Virtual cell' captures most-basic process of life: bacterial division Researchers simulated nearly every molecule in a bacterial cell — and then watched the cell grow and reproduce.

For the first time, researchers have simulated nearly every chemical reaction in a living bacterial cell

go.nature.com/4lrAulM

1 month ago 80 30 0 2
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AF2BIND: predicting small-molecule binding sites using the pair representation of AlphaFold2 Nature Methods - AF2BIND is a logistic regression model trained on AlphaFold2 pair features to predict small-molecule binding-site residues in proteins, without multiple sequence alignments,...

Our paper with @sokrypton.org using AlphaFold2 to predict small-molecule binding sites in proteins is now out in Nature Methods! 🧵
rdcu.be/e7SnX
www.nature.com/articles/s41...

1 month ago 67 21 1 0
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Let's get ready for a full month of training in image analysis in @pasteur.fr , this summer!

Are you interested in learning how to do bioimage analysis? For light microscopy? for cryo-EM? And for cellular cryo-EM?

Stay tuned, Pasteur offers access to THREE courses, this June.

👇🎓

1 month ago 29 28 3 0
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The registration is now open for BACELL meeting on 8-9 June 2026 at University of Malaga, Spain.

Register and submit abstract for oral or poster presentation: bacell2026.eu

Deadline for abstract submission: 31 March 2026
Registration deadline: 15 May 2026

Organizer @diegromero.bsky.social

1 month ago 9 9 0 0

✨ New postdoctoral opportunity in #cell biology at UNIGE!
@sophiemartinlab.bsky.social is looking for a postdoc to study cell–cell fusion.
Spread the word and see details below 👇@mocel.bsky.social @sciencesunige.bsky.socia

1 month ago 5 3 0 0

#MicroSky

1 month ago 4 3 0 0
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Save the date for the next International Conference on Gram-Positive Bacteria which will take place between 29 June–2 July 2027. The organizers (@annadragos.bsky.social, @polonca32.bsky.social, and Ines Mandic-Mulec) look forward to welcoming you to Ljubljana, Slovenia

1 month ago 17 10 1 0
Assistant/Associate/Full Professor Computational Biology Assistant/Associate/Full Professor Computational Biology

Join us as Assistant/Associate/Full Professor Computational Biology at Institute of Biology Leiden (IBL) / @leidenscience.bsky.social / @unileiden.bsky.social

Application deadline on 15 March 2026
👇
careers.universiteitleiden.nl/job/Assistan...

1 month ago 21 22 0 0
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SNIPE is a widespread bacterial defence system that exploits the spatial organization of phage genome injection to specifically target viral DNA, distinguishing self from non-self in prokaryotic immune systems @nature.com @mitpress.bsky.social
www.nature.com/articles/s41...

1 month ago 26 19 1 0
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Convergent MurJ flippase inhibition by phage lysis proteins - Nature A common mechanism of inhibition of the essential lipid II flippase MurJ by three distinct phage-encoded single-gene lysis proteins provides insights into potential new targets for antimicrobial devel...

Convergent MurJ flippase inhibition by phage lysis proteins www.nature.com/articles/s41...

1 month ago 30 12 0 0

How was the sleeper train to Glasgow? I love sleeper trains but only if they are smooth rides. Did Osaka to Tokyo and that was a dream. Sydney to Melbourne was horrible!

1 month ago 0 0 1 0
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The Origins of Agar First introduced into laboratories in 1881, agar remains indispensable as a culture medium.

The origins of agar
www.asimov.press/p/agar

1 month ago 28 10 1 4
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PhD & Postdoc Positions at the Dept of Microbial Population Biology of the MPI for Evolutionary Biology (Plön, Germany) to work on jumbo phages & HGT of genomic islands. An amazing research team led by the one and only Paul Rainey, one of the most hard-core evolutionary micro/biologists of our time!

2 months ago 8 9 1 0

In recognition of International Day of Women and Girls in Science, @plosone.org brings together perspectives from Section Editors and an insightful conversation with @clairebrockett.bsky.social from @sheffielduni.bsky.social on why inclusion matters ⬇️

#IDWGS2026 #WomenInScience

2 months ago 11 12 0 0
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The NUBee lab @Newcastle University have an exciting, fully funded opportunity to study Varroa, a major driver of honey bee colony losses.

The PhD complements ongoing work.
For more info (lnkd.in/eXKTNFcN) or contact Prof. Giles Budge.

2 months ago 3 2 0 0
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Dynamic DnaA–DnaB interactions at oriC coordinate the loading and coupled translocation of two DnaB helicases for bidirectional replication Abstract. Bidirectional replication is a conserved principle requiring coordinated translocation of the two replicative helicases loaded at the origin. In

Dynamic DnaA–DnaB interactions at oriC coordinate the loading and coupled translocation of two DnaB helicases for bidirectional replication url: academic.oup.com/nar/article/...

2 months ago 17 6 0 1
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Institut Pasteur (@pasteur.fr) is recruiting new young PIs to open new groups in the Institute. Deadline is February 9th! Don't miss the opportunity!

2 months ago 34 49 0 0

Check out these tools to detect co-evolution in protein-protein interactions developed by postdoc @chrislbgraham.bsky.social

Very useful as a hypothesis generator, complementing protein interaction prediction from Alphafold.

www.biorxiv.org/content/10.6...

2 months ago 16 8 2 0
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Identification of sporulation genes in Bacillus anthracis highlights similarities and significant differences with Bacillus subtilis How good is Bacillus subtilis as a model for the spore-forming pathogen Bacillus anthracis? Using high throughput genetics to identify B. anthracis sporulation genes and cytological analysis of the mu...

Fer’s tour de force in B. anthracis is out! Fer got Tn-seq running, built an ordered knockout library, defined all essential sporulation genes, and found a peptidoglycan deacetylase inhibitor critical for engulfment. Including our first one-by-all Alphafold screen! journals.plos.org/plosbiology/...

4 months ago 42 23 0 0
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PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

@poojag96.bsky.social work on the bioenergetics of spore germination is now published- Pooja had a really nice summary that I've put below but essentially we think the role of bioenergetics in spore germination has been completely overlooked!

www.pnas.org/doi/10.1073/...

3 months ago 16 8 1 0

I would love to attend this, but as things stand in the USA, I will have to miss it. Shocking incidents in the last couple of days...

3 months ago 1 0 1 0
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Just got word that we are a go for the Bacterial Cell Biology and Development GRS and GRC at Southern New Hampshire University!

GRS will be on June 5-6, 2027

GRC will be from June 6-11, 2027

Block off your calendars Prokaryotic Cell Biologists!

More details to come! Please repost!

4 months ago 62 37 3 2
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📢 Postdoc position: Biochemistry & Bacterial cell biology

in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"

🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025

Please repost. #Postdoc

5 months ago 29 31 1 1
Diagram of an E. coli cell showing polysomes pushing sister chromosomes apart.  Bottom heatmaps show cell-cycle-dependent
changes in DNA and ribosome density distributions, and constriction  formation. The top right corner shows normalized mid cell amounts from these heatmaps (integrated between the dashed horizontal lines).

Diagram of an E. coli cell showing polysomes pushing sister chromosomes apart. Bottom heatmaps show cell-cycle-dependent changes in DNA and ribosome density distributions, and constriction formation. The top right corner shows normalized mid cell amounts from these heatmaps (integrated between the dashed horizontal lines).

Our latest work is out in PNAS!🎉
We show that nonequilibrium polysome dynamics help drive sister chromosomes apart. The closing division septum also contributes via steric interactions.👇
www.pnas.org/doi/10.1073/...

#MicroSky #Microbiology #Biophysics #CellBiology

5 months ago 25 10 1 1