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Posts by Sarah Cobey

I’ve noticed a disturbing lack of ventilation in many hotel and motel rooms (even with the HVAC on) and unrelenting indifference from management. I have wished simple ventilation stats were available for hotel rooms, or that they didn’t pass their inspection in the first place.

3 days ago 4 0 1 0

🧪Totally disingenuous. The question is not whether the speakers you chose are popular or unpopular. The question is whether or not they are qualified. And an administrator cutting science for political purposes and suppressing scientific studies is not "advocating for scientific reforms".

1 week ago 146 15 0 0
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Remembering public health pioneer Barry Bloom: a scientist, a mentor, a mensch Marc Lipsitch and Yonatan Grad pay tribute to their former colleague and mentor Barry R. Bloom.

“It was Barry who discovered that lymphocytes-not macrophages, as some hypothesized-that carry immune memory. showed that lymphocytes signal to macrophages through a chemical they termed MIF-which, together w/ interferon, were the 1st cytokines discovered” www.statnews.com/2026/03/30/b...

3 weeks ago 13 4 0 0
Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success.

Data source: https://report.nih.gov/nihdatabook/report/302

Graph of award probability of R35 and R01 from NIH factbook as a function of review rank percentile. As is apparent, 2025 is a significant departure, with lower award probabilities at all scores <40 and significant departures from norm, where even being in the top 10% is no longer a nearly certain indicator of success. Data source: https://report.nih.gov/nihdatabook/report/302

The data is in: the NIH goalposts have shifted.

What were once almost certain fundable scores have become coin flips and what used to be likely grants have become aspirational, leading to fewer awards.

Another manifestation of how HHS policies have led to fewer awards and less science.

1 month ago 694 423 19 62

Here’s the full clip @whyshoulditrustyou.bsky.social

1 month ago 13 9 1 1

I completed an Open Science poll recently that asked what fraction of my papers were replication studies and struggled to remember a project that didn’t involve replication of others’ published work in some stage.

2 months ago 4 2 1 0

Dr. Bhattacharya recently came to U. Chicago for an "off the record" event. My strong impression was that he is truly unfamiliar with how most biomedical research works.

2 months ago 46 12 3 0
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We found that while close contact contributed to elevated risk (rate ratio 1.16 per doubling daily time, 95%-CI 1.01–1.33), time spent in shared classrooms and poor air quality had larger effects (RR 3.17, 95%-CI 1.96–5.17 and RR 1.90 95%-CI 1.23–2.94) respectively).

2 months ago 74 28 1 2

I get it, I just meant the purifiers that try to be ultra portable and don’t plug in aren’t solving any problem. N95 when moving or something small that plugs in that gives highest CFM at the filtration level you need.

2 months ago 2 0 0 0

(Some of the suggestions have been for purifiers to be worn around the neck, which isn’t as good as a N95.)

2 months ago 2 0 2 0

That’s true! I was thinking of more diverse exposures en route. Then whatever gives the best CFM at MERV-13 or whatever you need to filter out.

2 months ago 3 0 1 0

Your best bet is a N95.

2 months ago 2 0 1 0

This is a targeted attack on science media.

Bhattacharya has slammed science media for what he calls biased coverage, but how are our readers — the global scientific community — supposed to understand his new agency priorities if we can't even get in the door?

2 months ago 298 61 5 1

👯‍♂️👯‍♀️👯👯‍♂️

2 months ago 1 0 0 0

Just spoke to The Hill about how the dismantling of the NIH is impacting science in America. We still face a cliff of unfathomable heights, w easily 1000+ labs poised to close in the next year due to funding ending. A generation of young scientists lost because there is nowhere for them to train.

3 months ago 250 121 3 6
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Yes, we have a problem.

The problem starts at the top.

The problem is worsened by leadership of @nature.com & other journals & professional organizations who think that power demands a platform without scrutiny.

3 months ago 29 3 1 0

Isn’t it opening the wrong way?

4 months ago 7 0 2 0
Video

A bad thing is unfolding at NIH this week: It looks like the Trump administration is trying to replace key civil servant scientific leaders, the Institute Directors, with political hires. These directors control the NIH budget, tens of billions.

A bit of a video explainer here: 1/ 🧪

5 months ago 692 446 16 35
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Philanthropy, to the Rescue Having donated more than $19 billion since 2019, MacKenzie Scott ’92 is setting a new model for philanthropy, not just in the scope, but also in the way she gives

Her net worth is dropping: paw.princeton.edu/article/mack...

5 months ago 6 0 1 0

It was surreal to be quizzed on “freedom of inquiry” and other values in my mandated U. Chicago/NIH/NSF research security training tonight given the restrictions to our research over the past eight months. Jeremy describes the experience perfectly below. (His piece is outstanding.)

6 months ago 6 1 0 0
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Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404

6 months ago 127 127 4 1

Immigrants, particularly on H1Bs, are the lifeblood of American innovation. If you wanted to hurt US competitiveness in the next century, I can think of few more effective ways than a move like this

Even when found illegal, the mere intent will have irreparably harmed our future

7 months ago 129 36 5 1

This doesn’t affect your main point, but I think the imprinting/“original antigenic sin” hypothesis, in which differences in mortality arise from differences in early influenza exposures by birth cohort, has much more support.

7 months ago 5 1 1 0

But it does not *want* to do that. It has the personality and confidence of a 10x coder, and *absolutely lies to your face* to maintain the illusion.

It races to establish huge frameworks, call up parallel agents, and build you something that gives an output.

8 months ago 182 9 3 3
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Removed datasets: "Percent Positivity of Viral Detections Among Enrolled Children in the New Vaccine Surveillance Network (NVSN), Acute Respiratory Illnesses (ARI), 2017–Present" and "Pathogen Detections Among Enrolled Children in the New Vaccine Surveillance Network (NVSN), Acute Respiratory Illnesses (ARI), 12 Month Rolling Period"

Removed datasets: "Percent Positivity of Viral Detections Among Enrolled Children in the New Vaccine Surveillance Network (NVSN), Acute Respiratory Illnesses (ARI), 2017–Present" and "Pathogen Detections Among Enrolled Children in the New Vaccine Surveillance Network (NVSN), Acute Respiratory Illnesses (ARI), 12 Month Rolling Period"

Chart showing the deletion of data from the CDC's website over time, it starts with 1,488 items last year and currently stands at 1,398 items.

Chart showing the deletion of data from the CDC's website over time, it starts with 1,488 items last year and currently stands at 1,398 items.

NEW: I just observed two interesting data deletions from the CDC's website. Both having to do with vaccine surveillance in children. There's nothing about these datasets that would have tripped any "gender" flags.

You can still download them from our site: www.statnews.com/2025/02/14/t...

9 months ago 153 74 5 4

Just few days left to apply to one of these postdoc positions in my infectious disease modelling Unit at @pasteur.fr in Paris!

9 months ago 25 22 1 0

Coauthors are Bjarke Nielsen, Emily Howerton, and Bryan Grenfell. This work was mostly funded by the Life Sciences Research Foundation and NIH. Daniel is no longer on social media but is happy to answer any questions. [8/8]

9 months ago 4 0 0 0

Overall, quantifying pathogen resilience offers a new perspective on understanding how pathogens respond to both large and small perturbations. These insights have important implications for pathogen persistence, prediction, and model validation. [7/8]

9 months ago 2 0 1 0
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We've focused on resilience in the context of large perturbations. We also showed that resilience determines how sensitive a system is to smaller stochastic perturbations, with less resilient systems exhibiting greater deviations from deterministic trajectories under demographic stochasticity. [6/8]

9 months ago 2 0 1 0
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What determines how resilient a pathogen is? It depends on the per-capita rate of replenishment of the susceptible population. Faster replenishment = more resilient dynamics, where the rate of replenishment depends on the duration of immunity and basic reproduction number (R0). [5/8]

9 months ago 3 0 1 0