Congrats to Chase Morgan @phagemorgan.bsky.social and the phage team!

Congratulations to Doi Basu @dwaipayanbasu.bsky.social for publishing his first first-author paper from the lab!
The cryoEM structure of a tubulin-like protein from bacteriophage Goslar forms "microtubules" with nine protofilaments!
authors.elsevier.com/a/1mM253SNvc...

Graphical abstract showing the loop extrusion mechanism of the Wadjet complex, which selectively cleaves circular DNA while leaving linear DNA unaffected.

Happy to see our research on SMC Wadjet published in Molecular Cell. We showed DNA loop extrusion (LE) by a bacterial SMC, confirming LE is conserved across all life forms. Wadjet's LE activity is crucial for recognizing and restricting foreign plasmids, serving as a defense mechanism. 🧬🔬🧪

Structural diversity and oligomerization of bacterial ubiquitin-like proteins https://www.biorxiv.org/content/10.1101/2024.11.21.623966v1 Bacteria possess a variety of operons with homology to eukaryotic ubiquitination pathways that encod

Structural diversity and oligomerization of bacterial ubiquitin-like proteins www.biorxiv.org/content/10.1101/2024.11....

Mechanistic basis for protein conjugation in a diverged bacterial ubiquitination pathway https://www.biorxiv.org/content/10.1101/2024.11.21.623953v1 Ubiquitination is a fundamental and highly conserved protein post-translational modification pathway

Mechanistic basis for protein conjugation in a diverged bacterial ubiquitination pathway www.biorxiv.org/content/10.1101/2024.11....