Complex Patterns of Hitchhiking Mutation Load Among Stickleback Populations. New paper led by Jana Nickel out in GBE @genomebiolevol.bsky.social doi.org/10.1093/gbe/...

Genomic signatures of selection are enriched in differentially expressed genes in sticklebacks adapting to contrasting environments www.biorxiv.org/content/10.64898/2026.02...

Genomic signatures of selection are enriched in differentially expressed genes in sticklebacks adapting to contrasting environments www.biorxiv.org/content/10.64898/2026.02...

New paper out in Heredity: 'Evidence of long-term purging of mutation burden in killer whale genomes'. Time calibration of purging was through inclusion of an ancient (7.5Kyr) genome which was close to directly ancestral to the present-day population with signature of purging.
rdcu.be/eM25j

Experimental rewilding of stickleback drives phenotypic shifts that oppose long-term evolutionary trajectories in Daphnia in Alaskan lakes www.biorxiv.org/content/10.1101/2025.10....

Transposable elements drive much of naturally occurring genetic lethality in Drosophila melanogaster www.biorxiv.org/content/10.1101/2025.10....

'Ancient stickleback genomes reveal the early stages of parallel adaptation' - now published online in Evolution @journal-evo.bsky.social‬

Ancient stickleback genomes reveal the chronology of parallel adaptation www.biorxiv.org/content/10.1101/2025.04....

Rare Jackpot Individuals Drive Rapid Adaptation in Threespine Stickleback www.biorxiv.org/content/10.1101/2025.03....

Rare Jackpot Individuals Drive Rapid Adaptation in Threespine Stickleback www.biorxiv.org/content/10.1101/2025.03....

Clinical progression of clonal hematopoiesis is determined by a combination of mutation timing, fitness, and clonal structure www.biorxiv.org/content/10.1101/2025.02....

Blood-based Epigenetic Instability Linked to Human Aging and Disease www.biorxiv.org/content/10.1101/2025.02....

It’s not been working for me as well. The whole day :-(

Tracing the Spread of Celtic Languages using Ancient Genomics www.biorxiv.org/content/10.1101/2025.02....

Coancestry superposed on admixed populations yields measures of relatedness at individual-level resolution www.biorxiv.org/content/10.1101/2024.12....

Removal of toxic steroidal glycoalkaloids and bitterness in tomato is controlled by a complex epigenetic and genetic network A complex regulatory network controls the removal of toxic steroidal glycoalkaloids during tomato ripening.

Tomatoes lose their bitterness and toxicity as they ripen thanks to DNA demethylation, the hormone ethylene, and key transcription factors, finds a new #ScienceAdvances study. scim.ag/4bfdr8u

Estimating gene conversion rates from population data using multi-individual identity by descent www.biorxiv.org/content/10.1101/2025.02....

Accelerated genome shuffling associated with rapid evolution of sexual conflict in seed beetles www.biorxiv.org/content/10.1101/2025.02....

Local Adaptation of Life-History Traits in a Seasonal Environment www.biorxiv.org/content/10.1101/2025.02....

Not just mutations: Inbreeding depression persists without genetic variation www.biorxiv.org/content/10.1101/2025.02....

Variant effects depend on polygenic background: experimental, clinical, and evolutionary implications www.biorxiv.org/content/10.1101/2025.01....

Viral Simulation Reveals Overestimation Bias in Within-Host Phylodynamic Migration Rate Estimates Under Selection www.biorxiv.org/content/10.1101/2025.01....

Happy new year 🎆

I wish Zach Bryan’s Bathwater was much longer. What a beautiful song.

I’ve learned to be measured in all my dealings. It’s helped me to avoid a lot of unnecessary altercations.