Trump Slashed Funding for Science. Now the U.S. Faces a Costly Brain Drain.

Trump Slashed Funding for Science. Now the U.S. Faces a Costly Brain Drain. www.nytimes.com/2026/04/04/b...

📢Interested in #CancerMetabolism and #leukemia using mouse models in vivo? Come join us!! We're looking for a #postdoc to help us drive one of our multiple currently funded projects! Friends & colleagues, please RT!
👇👇👇
jobs.rutgers.edu/postings/262...

That’s one hell of a cover…..

Today is the anniversary of the April 1 RIFs at NIH and HHS.

Thinking of my colleagues who lost their jobs last year.

These cuts did no improve efficiency. They undermined the functioning of our government.

I’d be even more surprised if he actually shows up and plays the gig 🤣

I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

CANTAO: guiding clustering and annotation in single-cell RNA sequencing using average overlap - Molecular Systems Biology Single-cell RNA sequencing allows defining cellular identities based on transcriptional similarity using unsupervised clustering. However, a single clustering resolution may not yield groups of cells ...

You can find his results applying CANTAO and finally being able to distinguish DN thymocyte populations in scRNAseq data here 👇🏽👇🏽👇🏽

link.springer.com/article/10.1...

Proud of Chris being the first PhD minted from the Lab jointly with @hkhiabanian.bsky.social! @rutgerscancer.bsky.social

New approach methodologies: Don’t throw the baby out with the bathwater The NIH has recently called for expanding use of new approach methodologies (NAMs) to reduce use of animals in research. Arany discusses the need not to forget the irreplaceable aspects of animal rese...

SO much on point, thanks for pushing back Zoltan!

www.cell.com/cell-metabol...

This week's cover @thelancet.com

Screening, sorting, and the feedback cycles that imperil peer review The process of peer review is vital to contemporary science, but is also under enormous strain. This study uses mathematical models to dissect the threats to the long-term viability of peer review, su...

1. Kevin Gross and I have a new paper out today PLOS Biology.

We used economic models based around screening games and the market for unpaid labor to highlight a meltdown cycle threatening peer review.

F.D.A. Refuses to Review Moderna Flu Vaccine

NEW: The F.D.A. refused to accept an application from Moderna for its mRNA flu vaccine.

Its reason: The agency did not think Moderna compared the new vaccine to one of the best flu shots available. The company spent $750M+ on a 41,000 person study.

www.nytimes.com/2026/02/10/h...

Is your funding for hematology research "Between a rock and a hard place" #fightforhematology funds from ASH members and fans now provide a new program:
A R C H hematology.org/awards/caree...
NOTE: Are you doing well? .....your donations go 100% to lab support in the ARCH program.

Cite them as referencing to Product#XX or Other Significant Product#YY…add bold, line breaks, etc with html tags.
But overall, not sure who likes this new format tbh…

Bruce Springsteen - Streets Of Minneapolis (Official Audio) YouTube video by Bruce Springsteen

youtu.be/wWKSoxG1K7w?...

U.S. government has lost more than 10,000 STEM Ph.D.s since Trump took office A Science analysis reveals how many were fired, retired, or quit across 14 agencies

U.S. government has lost more than 10,000 STEM Ph.D.s since Trump took office | Science | AAAS www.science.org/content/arti...

No more calling them ICE. Time to call them Trump’s Death Squads.

Dear Ms. Fogel: I had applied for the position of Director of the National Institute of General Medical Sciences (NIGMS) on November 21, 2025. I was subsequently informed that I had passed the first level of review (although I have no idea what that means). I am writing today to withdraw my application. As I mentioned in my materials, it would be hard for me to consider this position, even it were to be offered, given two-career issues with my family. I saw this video this morning, posted on the official NIH Director's X account (https://x.com/NIHDirector_Jay/status/2013752138493559265). This made me fully realize that I should not waste my time or yours with my application as I cannot imagine working for NIH leadership that has so little respect for facts, the NIH and its staff, and the American public (and, I might add, themselves). Thank you for your attention to this matter. Sincerely yours, Jeremy M. Berg

I just withdrew my application for the NIGMS Director position....

From A1 percentile 10th to A0 ND…🤯

Line graphs of the new and competitive renewal awards from 2021 to 2026. The fiscal year 2026 curve is essentially zero with only 42 awards compared with more than 1200 through the same date in previous fiscal years.

Here is the curve for new and competitive renewal (Type 1 and Type 2) awards.

This reveals that only very few (42) new and competitive renewal awards have been made thus far in fiscal year 2026.

This compares with more than 1200 through the same date in previous fiscal years.

3/6

How am I supposed to live in the same country with people who believe or say such things, or with people who choose such representatives?

Fundamentally incompatible. This faction of US politics has to be defeated and has to face justice for its actions.

Nutrient requirements of organ-specific metastasis in breast cancer - Nature How the complex interplay between multiple nutrients within the microenvironment dictates potential sites of metastatic cancer growth is explored.

new out in Nature www.nature.com/articles/s41...

🤣

When I explain to people what is involved with writing a successful grant, they simply don’t believe me.

I explained it once to a famous person from Pixar, and he looked me square in the eye and said: You mean all the cancer and Alzheimer’s grants work that way? You’ve gotta be &$%#ing kidding me!

Congrats to both!! @kharaslab.bsky.social @bloodgenes.bsky.social

Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation Somatic mutations that increase the fitness of hematopoietic stem cells (HSCs) drive their expansion in clonal hematopoiesis (CH) and predispose individuals to blood cancers. Population variation in t...

New @science.org today
Discovery of a genomic variant that protects against blood cancer by reducing risk of CHIP (blood stem cell mutation clones, common with aging)
@bloodgenes.bsky.social
@kharaslab.bsky.social
science.org/doi/10.1126/...

Magic Johnson was the grand marshal of the Rose Parade today, and as someone who remembers his November 1991 HIV announcement: if you had told anybody that day that he would be alive and healthy 34+ years later, I don't think they would have believed you. Medicine and research—they work.

A dietary pan-amino acid dropout screen in vivo reveals a critical role for histidine in T-ALL Dietary interventions show therapeutic potential in cancer, but systematic comparisons are lacking. We performed a dietary pan-amino acid dropout screen in an orthotopic model of NOTCH1-driven T-cell ...

Which amino acid is most required for T cell leukemia?
Did you guess...histidine?
excited to see this out, congrats to Komal and @herranzlab.bsky.social and coauthors!
www.biorxiv.org/content/10.6...

A dietary pan-amino acid dropout screen in vivo reveals a critical role for histidine in T-ALL www.biorxiv.org/content/10.64898/2025.12...

Thanks so much to the funding agencies that supported these studies, most prominently @ludwigcancer.bsky.social and The V Foundation.

Now, may the review Gods be with us! 🤞