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Posts by James McDonald

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Call for papers! πŸ“„

Letters in Applied Microbiology invites articles exploring African soil microbiomes and their relation to soil degradation, desertification, salinisation, climate resilience, and food security. 🌱

Submit your research today πŸ”— https://ow.ly/cSNA50YNB8M

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Microbiome Medal featuring Earth at center surrounded by detailed microbial shapes and laurel wreath border.

Microbiome Medal featuring Earth at center surrounded by detailed microbial shapes and laurel wreath border.

Know a leader in microbiome research? 🧬

Nominations are open for the Microbiome Medal (est. 2025), recognising excellence in discovery & service. Open to scientists at any career stage.

πŸ“… Deadline: 10 April
πŸ”— www.psu.edu/news/researc...

#Microbiome #OneHealth #Microbiology

1 month ago 5 2 1 1

Really pleased to be speaking at this event. Come and join us in Switzerland!

1 month ago 6 3 0 0

Sending my sympathies, that’s rage inducing 😬

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Cool paper showing that microbiomes of mature trees can be resilient, with a preview by @zrojer.bsky.social and myself! www.sciencedirect.com/science/arti...

2 months ago 5 1 1 0

Thanks for writing a preview of the work!

2 months ago 1 0 0 0

@unibirmingham.bsky.social @imibirmingham.bsky.social @marccamb.bsky.social @drcarriebrady.bsky.social @cenococcum.bsky.social @alejandra1909.bsky.social

2 months ago 2 1 0 0
Preview
Microbial communities in semi-mature oak trees are resilient to drought, nutrient limitation, and pathogen challenge Global forest biomes face increasing stressors and disease outbreaks that threaten ecosystem health. Tree-associated microbiota are vital for tree res…

www.sciencedirect.com/science/arti...

2 months ago 2 1 1 0
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Delighted to see our work on the impact of drought on the oak microbiome featured on the cover of @cp-cellhostmicrobe.bsky.social
Link to the article below this post πŸ‘‡πŸ»

2 months ago 31 10 4 4

But what will replace it!? 😬

2 months ago 1 0 1 1

πŸŽ‰πŸŽ‰πŸŽ‰ New preprint to start the new year πŸŽ‰πŸŽ‰πŸŽ‰

Patients recovering from bowel surgery may have stomas formed to divert the flow of faeces to the opening on the skin, away from healing intestinal tissue. The visible sign of this process is an ileostomy or colostomy bag. /1

#surgerysky #medsky

3 months ago 3 4 1 0

Great to see you James, and great presentation!

4 months ago 1 0 0 0

Great to see you at #MMEG2025 @michiamausz.bsky.social and hear about the cool research being done in your lab!

4 months ago 0 0 0 0

Very much looking forward to 2 days of great talks at #MMEG2025, and to catching up with @resp-micro.bsky.social and @jamesemcdonald.bsky.social.

4 months ago 4 3 0 0

Who’s on their way to #MMEG2025 @unibirmingham.bsky.social today?

4 months ago 3 0 0 0

Now fixed, thanks for flagging this!

4 months ago 1 0 1 0

Let me check - will be back in touch!

4 months ago 1 0 0 0

Still time to register for MMEG but book fast to avoid disappointment!

4 months ago 5 2 1 0
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Great to be part of this work led by our collaborators @gathomas12.bsky.social and Jozsef Vuts @rothamsted.bsky.social

4 months ago 6 0 0 0
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πŸ“’ New preprint is out on bioRxiv πŸ“’:

How much does virome prep influence our view of the human gut virome?

Short answer: a lot.

Long answer:
doi.org/10.1101/2025...

Different methods lead to distinct community structures, richness, and major virus-host abundance patterns.

🧡 1/5

4 months ago 26 13 2 0

Thanks, Sofia! Hope all is well

5 months ago 2 0 0 0

The pre print of my PhD research is out! πŸ“£ Check it out for some cool results on high-throuhput microbial isolation, #SynComs and #Tree #Microbiome 🌳🧫
doi.org/10.1101/2025...
#PhDone πŸ’―

5 months ago 10 6 0 0

11/ πŸ“„ feedback welcome!
πŸ”¬ Huge thanks to our amazing team, collaborators and funders! @marccamb.bsky.social @cenococcum.bsky.social @drcarriebrady.bsky.social @bpettifor.bsky.social
BBSRC, NERC, DEFRA, Scottish Government.

5 months ago 1 0 0 0
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10/ Our work shows the potential of microbiome-based interventions for trees, just like those emerging in agriculture and human health. 🌍

5 months ago 1 0 1 0
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9/ This shows that tree microbiomes can be engineered to suppress disease β€” a promising strategy for forest health and conservation. πŸŒ²πŸ›‘οΈ

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8/ We then inoculated oak seedlings and logs with a disease-suppressive SynCom before pathogen challenge. The results were striking:
πŸ“‰ Brenneria goodwinii (oak pathogen) ↓ 56% (seedlings), ↓ 71% (logs)
πŸ“‰ Gibbsiella quercinecans (oak pathogen) ↓ 87% (seedlings), ↓ 95% (logs)

5 months ago 0 0 1 0
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7/ Next, we assembled synthetic microbial communities (SynComs) from these isolates. In vitro tests showed they could suppress oak pathogens. πŸ§ͺ

5 months ago 1 0 1 0
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6/ We screened 22,000 isolates on agar plates for their ability to suppress oak pathogens linked to Acute Oak Decline - 341 of the isolates showed strong pathogen suppression. πŸ’ͺ🌱

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5/ These isolates belonged to taxonomic groups that represented 61% of the total bacterial and 87% of total fungal sequences found in oak trees, based on 16S rRNA gene and ITS sequencing, respectively. A major resource for tree microbiome research! 🌳🦠

5 months ago 1 0 1 0
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4/ We processed tree tissue samples for isolation in the field within a few hours of collection to maximise chances of culturing key microbiota, using our mobile lab setup.

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