NOW PUBLISHED: Lowering FAIMS resolution on the Orbitrap Astral increases peptide identifications by 6-18% across sample loads from 250 pg to 16 ng, as demonstrated in new research from the Mechtler lab using Aurora Rapid 8×75 XT columns: bit.ly/4s0GELj
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@impvienna.bsky.social
Posts by Manuel Matzinger
I feel truly honored!😊 Thank you so much to everyone who contributed to our efforts in performing single cell proteomics at the Vienna BioCenter. Thank you so much also to the APMA selection committee for promoting our work (and those of many other talented young scientists)!
Excited to share our latest in vivo crosslinking workflow using a dual enrichment strategy: Over 5000 crosslinks and 56 novel PPls- Huge thanks to the amazing team: Philipp Bräuer, Laszlo Tirian, Fränze Müller, Karl Mechtler at the Vienna BioCenter who made this possible! doi.org/10.1038/s420...
Check all the details and take the chance to register: www.apma.at/6thescp/
Participation is free of charge thanks to our generous sponsors!
The deadline to submit abstracts and register for this years symposium on single cell proteomics #ESCP25 in Vienna is approaching this Sunday! This year we additionally host a workshop for deep visual proteomics and a Thermo User Meeting.
If you're interested also check out 2 other recent exciting XL-MS studies from our group, checking XL-MS performance on the Astral (www.biorxiv.org/content/10.1...) as well as on reagent development progress and limitations (www.biorxiv.org/content/10.1...)
Excited to unveil our new, efficient & easy to implement workflow for in vivo XL-MS! 🎉 It delivers a comprehensive PPI network already from a single fraction measurement, saving valuable MS time and resources.
www.biorxiv.org/content/10.1...
What do Europeans think of science and technology?
- 83% believe science and tech have a positive impact,
- 67% say science makes life easier, healthier and more comfortable,
- 58% want to learn more about scientific advances.
Find out more in the new Eurobarometer.
ec.europa.eu/commission/p...
Learn more about a new single-cell proteomics workflow that enables an unprecedented level of protein quantification at the single-cell level developed at the Proteomics Tech Hub at Vienna BioCenter lnkd.in/dMR55uRw
Biggest challenge facing the proteomics community? To Manuel Matzinger, Senior Scientist & Deputy Head, Proteomic Technology Hub, Vienna BioCenter - it’s controlling false discovery rate.
Manuel discusses his journey into the field, his One-Pot Workflow & the role of technology.
Read his feature:
It gives me great pleasure to announce our next European Single Cell Proteomics Conference www.apma.at/6thescp/
We would be delighted to receive many abstracts from students so that they have the opportunity to give their first presentation.
On behalf of: Erwin, Fabian, Manuel, Fabian and Karl