Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome UPF1 depletion inhibits nonsense-mediated mRNA decay (NMD) and stabilizes direct target transcripts within hours. Boehm et al. use conditional protein degradation and advanced transcriptomics to map t...

Very harmonious and inspiring collaboration with Niels Gehring, @volkerboehm.bsky.social and team at Uni Köln, and colleagues at @mdc-berlin.bsky.social . Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome: Molecular Cell www.cell.com/molecular-ce...

Life-saving cancer drug takes next step in clinical development | Institute of Genetics and Cancer | Institute of Genetics and Cancer A drug candidate for hard-to-treat cancers, developed in the Institute of Genetics and Cancer (IGC) and now licensed to Nuvectis Pharma, has moved to the next stage of clinical trials after successful...

A drug candidate for hard-to-treat cancers, developed by Profs Neil Carragher and Asier Unciti-Broceta at #IGC and licensed to Nuvectis Pharma, has moved to the next stage of clinical trials. Read more here: edin.ac/3UuvJeo
@edinnovations.bsky.social

Congratulations to David Tollervey! He received this year's RNA Society Lifetime Achievement in Science Award. @rnasociety.bsky.social

Join us in San Diego. A great meeting and also featuring the RNA Journal

Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape - Genome Biology Background Centromeres depend on chromatin containing the conserved histone H3 variant CENP-A for function and inheritance, while the role of centromeric DNA repeats remains unclear. Retroelements are...

Our paper on a centromere-enriched retroelement is out! link.springer.com/article/10.1... Congratulations to all the authors! Comments and reposts welcome and appreciated 🧬🔬

Looking for a new home to share all things RNA. That other place was just too crazy. Excited to see so many old RNA friends here on this platform! #RNA

New EdiRNA events for the new year! Funded by the @RNASociety. Great opportunity to network with other RNA biologists 🧬 (dsRNA included) from Edinburgh and beyond 🚀
Jan 29, 2025
Apr 9, 2025
Jun 11, 2025
Oct TBD, 2025

www.edirna.com/meetings