Much deserved, congrats!

Local agricultural transition, crisis and migration in the Southern Andes - Nature In the Uspallata Valley, agriculture was adopted by local populations, as evidenced by genetic continuity from earlier hunter-gatherers to farmers; maize-dependent groups from the same regional p...

How did farming reach the Southern Andes? Through migration or cultural transmission? Our new paper in @nature.com combines ancient DNA, isotopes, archaeology & paleoclimate to reconstruct 2,000+ years of history in Uspallata, Mendoza.
www.nature.com/articles/s41...
A Thread🧵 (1/25+)

Clonal-aggregative multicellularity tuned by salinity in a choanoflagellate - Nature The choanoflagellate Choanoeca flexa forms motile and contractile cell monolayers purely clonally, purely aggregatively or through a combination of both processes depending on environmental condi...

Salinity tunes mode of multicellularity in a tidepool choanoflagellate www.nature.com/articles/s41... - paper in @nature.com

We recently deployed our favorite “lab in a suitcase” dynamic duo of #BentoLab and ONT #MinION to conduct real-time, in country multiplexed modular malaria amplicon sequencing by #MAD4HatTeR to inform public health policy decisions in Chad! #DecentralizedGenomicSurveillance

Get ready for the best meeting in 2026!

This one is for the best team and colleagues I could wish for! Thank you @pasteur.fr for having us and @embo.org for all the support.

Congrats to all other new YIPs, very honored to join this amazing pool of scientists.

@jessmbryant.bsky.social
@tizvignolini.bsky.social
@ju-couble.bsky.social

Mid-career Group Leader position in AI in genomics at Institut Pasteur, Paris - Research Institut Pasteur and the CNRS are launching a call for a mid-career group leader position in AI in genomics. We are looking for an experienced researcher (typically with > 8 years of research experien...

There a is a joint call between @pasteur.fr and @cnrsbiologie.bsky.social for a mid career group leader position in AI and genomics (or molecular biology). Don't hesistate to spread the word if you know anyone relevant.

research.pasteur.fr/en/call/mid-...

Just uploaded our new preprint to @ecoevorxiv.bsky.social

Multinucleate life really is everywhere...from deep sea forams to slime molds, intracellular parasites, and beyond. 🚀

We explore how scaling, ecology, & evolution intersect when many nuclei share a single cytoplasm.
doi.org/10.32942/X2M...

Innate immune responses to Plasmodium falciparum disrupt the blood-brain barrier Plasmodium falciparum accumulation at the blood-brain barrier (BBB) is a hallmark of cerebral malaria, a life-threatening complication. Conversely, the contribution of the immune response to vascular ...

Pre-print alert 🚨
We answer a longstanding question in the field. Do immune cells cause cerebral malaria?

The answer is YES!!!! And independently of P. falciparum accumulation in the brain.

www.biorxiv.org/cgi/content/...

Beautiful beasts: excited to see our first volume electron microscopy study on malaria parasites published: advanced.onlinelibrary.wiley.com/doi/10.1002/... revealing new insights into Plasmodium ookinete development. Thanks for great EMBL-Umea-Heidelberg collaboration.

Come apply with us to unravel some beautiful malaria genetics! This is a great program with plenty benefits specifically for international students

Parasite genome organization: come together, right now! Links between genome organization and transcription have been extensively studied in model eukaryotes; however, recent application of state-of-the-art chromosome conformation capture techniques to kin...

We @singh-parul.bsky.social teamed up with the amazing @fariatrypslab.bsky.social @trypsleon.bsky.social to highlight how recent technological advances have revealed exciting new features of parasite genome architecture and its impact on survival and pathogenicity:

www.cell.com/trends/paras...

Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model Nature Communications - Here the authors show that Plasmodium falciparum egress products disrupt endothelial barrier and activate JAK-STAT and interferon type response in a 3D blood-brain barrier...

We are happy to show one ourt first exciting papers. We have developed a blood-brain barrier model to study the disruptive effects caused by the malaria parasite, Plasmodium falciparum.

First, congratulations to the fearless @liviapiatti.bsky.social and @alinabatzi.bsky.social

rdcu.be/ezBl7

🚨 2-year post-doc position available in my lab. More details below. Please repost!

acrobat.adobe.com/id/urn:aaid:...

A two year post-doctoral position at the BacterialGenome Plasticity Unit starting October 1st - Research

A 2-year postdoc position in my lab, under the supervision of P-Alex Kaminski, on Z-DNA phages and the benefit given by ZTGC DNA and the replication machinery, with attempt to create a Z based minireplicon
research.pasteur.fr/en/job/a-two...

📣 I'm recruiting a postdoc researcher to join my team for a project on mosquito-specific viruses and host interactions. Peep the job description & how to apply below. Perfect for soon-to-be or recent PhD graduates in mosquito vector biology 🦟 or arbovirology 🦠
🗓️ Application deadline 31 August 2025

Preprint Alert 🚨 Check out the latest piece of work from the @kirkdeitsch.bsky.social lab, where we characterized the sophisticated molecular layers controlling var2csa expression and antigenic variation in P. falciparum

Pre-print alert 🚨: We have developed 2D and 3D stable iPSC endothelial-differentiation models through dox inducible ETS expression. We demonstrate endothelial identity and used these models for studying malaria pathogenesis research. www.biorxiv.org/content/10.1...

June was a productive month: brought two things into this world, both of which were great collaborative efforts and about nine months in the making. Check out where we map P. falciparum genome architecture at high resolution with Micro-C here:

www.nature.com/articles/s41...

Supported by @erc.europa.eu @pasteur.fr @agencerecherche.bsky.social

How does the malaria parasite regulate co-expression of genes? By recruiting them into transcription factories, courtesy of MORC et al. A fantastic team effort led by @jessmbryant.bsky.social with Jacques Serizay @singh-parul.bsky.social, @ju-couble.bsky.social @rkoszul.bsky.social

An atypical Arp2/3 complex is required for Plasmodium DNA segregation and malaria transmission - Nature Microbiology A unique Arp2/3 complex in malaria parasites enables DNA segregation during the rapid formation of male gametes by safeguarding the attachment of chromosomes to the mitotic spindle.

Awesome malaria study out now in Nature Microbiology:

An atypical Arp2/3 complex is required for Plasmodium DNA segregation and malaria transmission

By Franziska Hentzschel, Matthias Marti, Freddy Frischknecht & colleagues!

@freddyfrischknecht.bsky.social

www.nature.com/articles/s41...

📢 Big Announcement: Registration & abstract submission open for EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by ParaFrap @parafrap.bsky.social @embo.org

🗓️ 5-8 Oct 2025 - Les Embiez Island-France

🔚Deadline: 15 Jul 2025 meetings.embo.org/event/25-hos...

Special shout-out to the presentations from our very own Selina Mussgnung and @thebeilab.bsky.social from the Institut Pasteur network in Dakar!

As usual, fantastic science at #EMBLMalaria. Special thanks for the travel support from @pasteur.fr in the new EMBL-Pasteur initiative and the organization @lilianamancio.bsky.social @sturalph.bsky.social @events.embl.org

scRNA-seq reveals transcriptional plasticity of var gene expression in Plasmodium falciparum for host immune avoidance Nature Microbiology - Single-cell transcriptomics revealed that malaria parasites have unexpected flexibility in surface antigen expression, potentially providing parasites with greater adaptive...

Very happy to congratulate @fra-florini.bsky.social and Joe Visone for the publication of their recent work on antigenic variation by malaria parasites: rdcu.be/emjbn and an earlier version here: www.biorxiv.org/content/10.1.... Francesca will present some of this work next week at BioMalPar 2025.

Parasites need mitochondrial respiration to infect and spread. Effective anti-malaria and ani-toxoplasmosis drugs target respiratory complexes (e.g. atovaquone)!

But how do the parasite complexes work and how do drugs inhibit them?

Read Andrew Maclean and Alex Mühleip phenomenal work on this! 👇

The KnuepferLab is hiring!

Our team is looking for a highly motivated, experienced molecular parasitologist to expand our group as a postdoctoral researcher at the RVC.

Follow either link below for more information on the project and the job offer:
lnkd.in/eprgmaE9
www.jobs.ac.uk/job/DMY962/p...

Invitiation to attend "Prioritising in a crisis: What next for malaria research?" Friday 25th April 12.30 BST https://www.lshtm.ac.uk/newsevents/events/prioritising-crisis-what-next-malaria-research

Looking forward to joining @lshtm-malaria.bsky.social’s #WorldMalariaDay event to reflect on what’s next for malaria research and how we can continue to drive change.
Details here www.lshtm.ac.uk/newsevents/e... | LSHTM
#Malaria #GlobalHealth #WorldMalariaDay

@erc.europa.eu @pasteur.fr