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Posts by Karla Satchell

We are on the move and this year will be held in beautiful Southbridge, Massachusetts at the height of leaf changing season. Conference is organized by toxin biologists for the toxin biology community. Come join us!

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Conference banner showing trees with leafs changing colors.

Conference banner showing trees with leafs changing colors.

Announcing the 4th Lakeside Conference on Protein Toxins and Effectors 2026 Registration/Abstract Submission is OPEN (#lakesidePTE)! Come join this premier event on the structure, biochemistry, and cell biology of Microbial Protein Toxins Oct 12-15, 2026. event.fourwaves.com/lakesidepte2...

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I thought that was Nature group journals. Don’t you already work for that publication? Academics pay thousands and 10,000+ to publish in Nature publications. Can’t you just ask the editor one desk over?

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Quote from Paper “This trend raises questions about whether research papers can remain a reliable method for sharing scientific progress.”

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Finally, I want to inform readers that my lab has been at the forefront for >15 years on understanding how these bacteria cause disease. However, we are struggling because, as a Northwestern Faculty member, my grants to study these infections have been frozen since March. Please Support Science!

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Genetic Divergence of Vibrio vulnificus Clinical Isolates with Mild to Severe Outcomes | mBio Vibrio vulnificus is an aquatic pathogen that is capable of causing severe disease in humans. Previous studies have suggested that pathogenic isolates were restricted to certain phylogenetic lineages ...

Studies from my group have shown that Vibrio vulnficus bacteria from around the phylogenetic tree can cause infections in humans. So there are not good Vv and bad Vv...they are all bad. Just some may be much worse.
journals.asm.org/doi/10.1128/...

7 months ago 0 0 1 0
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S3249 A Deadly Case of Vibrio vulnificus Bacteremia After... : Official journal of the American College of Gastroenterology | ACG An abstract is unavailable.

Vibrio vulnificus is also the leading cause of seafood-borne death. I love oysters...I recommend po' boys with fried oysters, grilled, and stews. But always cooked, especially in the warm months of the year. Shrimp and other seafood also can be sources of infection. journals.lww.com/ajg/fulltext...

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Vibrio vulnificus septic shock due to a contaminated tattoo We present a case of Vibrio vulnificus septic shock and cellulitis in a patient with chronic liver disease that occurred after obtaining a leg tattoo with subsequent seawater exposure in the Gulf of Mexico. Initial suspicion for V. vulnificus was high and he was started on empiric doxycycline and ceftriaxone at admission. Blood and wound cultures grew oxidase positive and comma-shaped Gram-negative rods ultimately confirmed to be V. vulnificus. Despite aggressive initial treatment, the patient developed septic shock and died. This case highlights the association of chronic liver disease and high mortality associated with infections of V. vulnificus . Health providers should remain vigilant for V. vulnificus infections in patients with chronic liver disease and raw oyster ingestion or seawater exposure.

Caution should be taken when walking in brackish waters and swimming. Common clinical cases include cuts while fishing, walking in shallow waters with small cuts on feet, and this one of infection while swimming with a new tattoo. casereports.bmj.com/content/2017...

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How to protect yourself from Vibrio vulnificus, the bacteria found in some coastal waters States are warning beachgoers about a summertime surge in infections from a frightening, flesh-eating bacteria found in coastal waters.

The annual news blitz about danger this time year of Vibrio vulnificus is upon us. If you live in the Gulf or Atlantic areas, and particularly if you have liver disease, cancer, or immunosuppression, Vv is a danger. The disease is rare but death rates high, survivors have long hospitalizations 🧵

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Great time with my awesome Northwestern colleagues at #GRCMAST

8 months ago 3 0 0 0
A happy scientist holding a poster prize certificate

A happy scientist holding a poster prize certificate

Congratulations to Mason Clark who won the @fems MicroLife poster prize at the Microbial Adhesion and Signal Transduction GRC!

8 months ago 33 5 1 1
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Northwestern Micro representing at the 2025GRC MAST conference in beautiful Newport. Great science, collegial people but there’s a cloud hanging over us all. ☁️

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“NIH will introduce a cap on allowable publication costs starting in Fiscal Year (FY) 2026, ensuring that publication fees remain reasonable across the research ecosystem. The policy aims to curb excessive APCs & ensure the broad dissemination of research findings w/o unnecessary financial barriers”

9 months ago 15 7 2 0

This is an event on Tuesday in the House of Representatives hosted by the minority Science committee, led by @lofgren.house.gov.

Real question: why isn’t this being held in the evening and produced for TV and social media?

There are production and storytelling resources in Congress.

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Kennedy’s HHS Sent Congress ‘Junk Science’ To Defend Vaccine Changes, Experts Say - KFF Health News A look inside the Department of Health and Human Services document citing vaccine misinformation that could influence congressional perceptions.

"A document [DHHS] sent to lawmakers to support Secretary Robert F. Kennedy Jr.’s decision to change U.S. policy on covid vaccines cites scientific studies that are unpublished or under dispute and mischaracterizes others."
kffhealthnews.org/news/article... via @kffhealthnews.org

10 months ago 354 120 18 14
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The MAHA Report Cites Studies That Don’t Exist The Trump administration’s “Make America Healthy Again” report misinterprets some studies and cites others that don’t exist, according to the listed authors.

RFK Jr's "MAHA" report is filled with references to studies that literally do not exist, or that completely misinterpret the studies' findings.

“We did not publish a paper.. on this topic with that co-author group, or with that title,” says one cited researcher.

www.notus.org/health-scien...

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Thanks to Northwestern Feinberg communications for writing this nice article on our recent work for the newsletter. @vibrio-vulnificus.bsky.social

11 months ago 18 2 2 0
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Great new study by my excellent colleague @jutraslab.bsky.social on treatments for Luke’s disease

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To say it once more today: I think you'll be moved if you take 2 minutes to look through 269 institutions signed on here.

Yes, still a few notable absences. (Where is Stanford?) But such an array of *presence.* Big and small. Public and private. World famous and barely known. Check them out.

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Graduate student Jiexi Chen presented today in the emerging scientist session #ASBMB25 on her new paper on toxin binding N-glycans. She did a great job!!

1 year ago 12 1 1 0
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Vibrio MARTX toxin binding of biantennary N-glycans at host cell surfaces The large pore-forming toxin MARTX with broad tissue tropism binds the essential unit of N-glycans on eukaryotic cell membranes.

Taking a break from the news in Bsky. Happy to share amazing study by student Jiexi Chen on Vibrio vulnificus MARTX toxin engagement of N-glycans and receptor L1CAM. First study on this toxin binding to cell surfaces. #vibrio #microsky #toxins www.science.org/doi/10.1126/...

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Was great to participate in this project designed to test robustness of AI ligand prediction but had a side benefit of crowd-sourced discovery of a SARS-CoV-2 helicase inhibitor

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Hi @schakowsky.house.gov The weather is supposed to be nice for @standupforscience.bsky.social Rally for Science on the National mall. I am coming from Evanston, hope to see my rep there too!!

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How DOGE’s Cuts to the IRS Threaten to Cost More Than DOGE Will Ever Save The Trump administration claims gutting federal agencies will save money, but cutting the IRS means the government collects less taxes. “If you’re interested in the deficit and curbing it, why would y...

Slashing IRS staff will end up costing the U.S. government.

Multiple studies have shown that for every dollar spent by the IRS, the agency returns between $5 and $12.

New @propublica.org by @andykroll.bsky.social

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They can use AI bots on their side to save time/cost to replace editors, and now trying to normalize this behavior to get reviewers to volunteer more often so they can grow revenue.

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Nature is responding to a critical flaw in their business model, they need to grow revenue to keep billionaire investors on board, but depend on volunteer peer reviewers.
1/n

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Wonderful recognition! Hank gave great speech at ceremony on how service and faculty joining together is most important in challenging times

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Order out of Chaos | NEJM Eric Rubin comments on the effects of the raft of executive orders from the current administration on scientific research and public health.

www.nejm.org/doi/full/10....

1 year ago 10 4 0 1
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Stand up for Science · Indivisible Chicago Science is for everyone–and benefits everyone. When the federal government supports scientific research through taxpayer funding, it fuels innovation, creates jobs, and sustains the world we live in...

🗽🔬 STAND UP FOR SCIENCE. Chicago joins the nationwide movement to demand that our government fully support scientific research, which employs people, benefits our economy, and SAVES LIVES

Join Indivisible Chicago & @standupforscience.bsky.social on Fri, March 7th, 12pm, Federal Plaza. Info/Sign-up:

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