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Posts by Guido Meijer

Yep that's me, with excellent / outstanding reviews as well πŸ₯²

2 days ago 1 0 0 0

Do you record spikes in vivo? Here are two recently recommended preprints on toolboxes for extracellular electrophysiology:
-MLIB doi.org/10.1101/2025... by Maik StΓΌttgen.
-Power Pixels doi.org/10.1101/2025... by @guidomeijer.com and @battaglialab.bsky.social.

2 days ago 6 2 1 0
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ERC President explains stricter application measures amid rising demand for funding The text of an open letter sent by ERC President Maria Leptin to ERC panel members, grantees and other stakeholders on 16 April 2026.

The ERC is changing the rules retroactively!

A "B" grade now carries a 2-year timeout instead of 1, even for those who submitted under the old rules. Researchers (incl me) make massive career decisions based on these timelines, you can't change them after the fact πŸ˜΅β€πŸ’«

erc.europa.eu/news-events/...

3 days ago 7 1 1 0
Power Pixels: a turnkey pipeline for processing of Neuropixel recordings

The Power Pixels ⚑ pipeline is out now in Peer Community Journal!

Are you doing Neuropixel recordings but don't have a pre-processing pipeline yet? Check out this end-to-end pipeline designed to simplify preprocessing of Neuropixel recordings 🧠

peercommunityjournal.org/articles/10....

1 month ago 5 0 0 0
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A prefrontal cortex map based on single-neuron activity - Nature Neuroscience The authors mapped spontaneous and choice activity across mouse prefrontal cortex. The activity maps aligned with intrinsic connectivity rather than anatomical subregions, suggesting that connectivity...

Main postdoc study out! We can redefine prefrontal cortex regions with single-unit activity! Grateful to @carlenlab.bsky.social and @weltgeischt.bsky.social who made this crazy project real. Thanks to all co-authors, collaborators, and reviewers.
www.nature.com/articles/s41...

3 months ago 97 21 5 3
BOLD signal changes can oppose oxygen metabolism across the human cortex, Nature Neuroscience

BOLD signal changes can oppose oxygen metabolism across the human cortex, Nature Neuroscience

fMRI signals β€œup,” but neural metabolism might be going β€œdown.”

In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes.

rdcu.be/eUPO8
funds @erc.europa.eu
#neuroskyence 🧡:

4 months ago 176 80 4 8
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The Power Pixels pipeline just keeps getting better! The latest update comes with:
- OpenEphys support
- AP_Histology support
- automatic high-frequency noise reduction
- NWB format export option
- zarr compression of raw data

And, most importantly: a cool new logo!

github.com/NeuroNetMem/...

5 months ago 9 1 0 0

Halloween isn’t my thing. My idea of a scary night is reading the plots of horror movies on Wikipedia.

5 months ago 2 0 0 0

I never understood why everyone always complains about the clocks changing.
Then I had a kid.

5 months ago 9 0 0 0
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Thanks! I always save the illustrator file as an editable pdf, that way it is self contained even when the panels are technically links.

5 months ago 0 0 1 0

Thanks! Yes, that's a good way of doing it if you don't like Illustrator, I just find it way too time consuming to position everything programmatically (and I have free Adobe through my uni 😁)

5 months ago 1 0 0 0

I didn't know that, that's cool!

6 months ago 1 0 0 0
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Google Colab

I hope you found this useful! Here is a Google Colab with example code of what was discussed in this thread:

colab.research.google.com/drive/1UlCET...

6 months ago 11 1 2 0

The workflow: Python plots single panels, saved as pdfs. Create an empty figure of 7 inch (180 mm) wide in Illustrator and place the panels as links. Add the panel letters (a,b,c). Now, if a new version of a panel is generated you just have to click update links in Illustrator and it's there. 🀩

6 months ago 3 0 2 0
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A note about colors 🌈 Imagine you made eight figures and your PI asks you to change the color of an element you've consistently plotted green into orange. If you define your colors in the plotting function you only have to change it there and rerun the plotting scripts, this save a lot of time!

6 months ago 3 0 1 0

Full width figures typically have four panels next to each other, a good rule of thumb is that a single panel is 1.75 by 1.75 inch. Create two figure panels like this:

f, axs = plt.subplots(1, 2, figsize=(1.75 * 2, 1.75), dpi=300)

⚠️ If it's too small increase the dpi, not the figsize!

6 months ago 2 0 1 0
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The font size of each plot element can be easily set with seaborn. Write a function like this that sets the font size and any other style element you like to have in all your plots and the function each time before plotting (link to the code in the last post).

6 months ago 4 0 2 0

Journals have criteria figures have to adhere to. Generally, a full-width figure should be 7 inch wide and font sizes cannot be smaller than 7 pts. If you get into the habit of always creating figures that fit these criteria this will save you a lot of time when submitting.

6 months ago 3 0 1 0
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Want to make publication-ready figures come straight from Python without having to do any manual editing? Are you fed up with axes labels being unreadable during your presentations? Follow this short tutorial including code examples! πŸ‘‡πŸ§΅

6 months ago 158 46 2 4
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I was doing the second-to-last recording of my project and was happily thinking to myself that I haven't broken a single Neuropixel in the entire two year project.

You can guess what happened next...

Now I have to install a new probe just for one final recording πŸ™ƒ

6 months ago 9 0 0 0
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I love how they came up with all this random stuff but for this one area they were like "I really don't know, just put a question mark"

6 months ago 22 3 3 0

Getting a hundred bucks would have been nice! We had to pay them twelve thousand bucks instead.

6 months ago 1 0 1 0

When I told my dad I published in Nature he was like "wow, you must have made a lot of money with that"

7 months ago 16 0 1 0

Of course, that makes complete sense πŸ™ƒ

7 months ago 1 0 0 0
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I don't know why people say X is going down the drain, my last post got lovely replies like this one:

7 months ago 3 0 2 0
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Want to collaborate with the International Brain Laboratory on your own project? We have funding to work with groups anywhere in the world to do new large-scale projects and we are looking for new partners! Learn more and apply: www.internationalbrainlab.com/ibl-core-apply

7 months ago 25 14 1 2
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Thrilled to share that our work is now published in Science! ✨

We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭

www.science.org/doi/10.1126/...

🧡1/

7 months ago 175 72 8 6
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If you're into podcasts, here's a good one on the @intlbrainlab.bsky.social brainwide map, by @newscientist.com

www.newscientist.com/podcasts/fir...

7 months ago 9 1 0 0
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A brain-wide map of neural activity during complex behaviour - Nature The International Brain Laboratory presents a brain-wide electrophysiological map obtained from pooling data from 12 laboratories that performed the same standardized perceptual decision-making task i...

Sad day for peope who still believe brain areas are the primary organizational units of function in the brain.

www.nature.com/articles/s41...

7 months ago 211 52 11 17
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How Do Our Brains Make Decisions? The International Brain Laboratory Is Closing In on Answers How Do Our Brains Make Decisions? The International Brain Laboratory Is Closing In on Answers on Simons Foundation

The β€ͺ@intlbrainlab.bsky.social published 2 papers today on their work to create a map of neural activity across the entire mouse brain. Learn more about the lab: www.simonsfoundation.org/2025/02/20/how-do-our-br...

7 months ago 24 8 0 0