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Posts by Ben Langmead

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Higher education groups challenge Trump’s latest anti-DEI order A coalition of organizations is suing over a directive that threatens to strip federal contracts from colleges over their diversity, equity and inclusion efforts.

We are proud to be a part of this coalition suing to stop the Trump administration from stripping federal contracts from colleges & universities over their diversity, equity & inclusion efforts.

We shouldn’t be here, but here we are.

4 hours ago 56 16 0 0

The number of NIH competitive awards is down 50% from 2025, and down ~70% from prior years. Even if they catch up by the end of the year, only wealthy institutions can bridge these huge funding gaps.They're killing science-and violating the constitution-by weaponizing the bureaucracy

14 hours ago 199 149 8 8
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C.D.C. Cancels Publication of Study Showing Benefits of Covid Vaccines

The acting head of the CDC has canceled the publication of a study that found that the Covid vaccine sharply cut the odds of hospitalizations and emergency visits last winter

www.nytimes.com/2026/04/22/u...

13 hours ago 884 539 32 90

Superb list of new Fellows. Very excited to see colleague Ela Pertea there. Also very glad to see Gonzalo Navarro recognized; a wise move by ISCB recognizing how computer science theory (pattern matching, text indexing) has supercharged progress in genomics and pangenomics. Congrats, Fellows!

1 day ago 6 0 0 0
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Excited to be inducted as Fellow of the American Institute for Medical and Biological Engineering! Advocacy for the #medical and #biological #engineering #sciences is more important now than ever. Thank you #AIMBE! 🧬 🧪 🖥️ @aimbe-official.bsky.social

www.bme.jhu.edu/news-events/...

2 days ago 25 3 1 0
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In August, Jay Bhattacharya said “Training future biomedical scientists” was the 1st priority for his version of NIH.

But talk is cheap. Let’s see how JB’s doing. 🤔

NIH supports trainees mostly via fellowship (F), training (T), and career development (K) awards.

Here are funding curves for each.🧵

2 days ago 116 81 5 15

It's a very happy day indeed when I can welcome such a superb scientist and good friend to the JHU family. Adam & @mikeschatz.bsky.social were TAs for the first genomics course I took, taught by @stevensalzberg.bsky.social, and they've been role models since. JHU students: take Adam's courses!

2 days ago 28 0 1 0
We're moving! Friday was my last day at NHGRI. After 10 wonderful years, my lab is headed one hour north on I-95 to set up shop at Johns Hopkins University. This is a very bittersweet move for me, as NHGRI has prov...

Friday was my last day at NHGRI. After 10 wonderful years, my lab is headed to Johns Hopkins University
genomeinformatics.github.io/movingday/

3 days ago 133 19 15 1
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The AI Rewrite Dilemma

Blog post on "The AI Rewrite Dilemma": lh3.github.io/2026/04/17/t...

5 days ago 54 29 3 4
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Early Career Faculty Program | Freeman Hrabowski Scholars | HHMI The Freeman Hrabowski Scholars Program offers comprehensive support to outstanding early career faculty committed to scientific excellence in their own research, and to fostering labs that expand the ...

This program transformed my career! Please apply.

@hhmi-science.bsky.social's #FreemanHrabowski Scholars Program offers early career faculty up to $10M over 10 yrs, plus salary & benefits. Postdoc? This year's competition has a program for you too. Applications open 11/3! bit.ly/4vhC0LA

6 days ago 80 45 0 2
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Nobel Prize winner Katalin Karikó to be 2026 Commencement speaker On Tuesday, April 7 a leaked University video announced that Katalin Karikó will deliver the commencement speech for the Class of 2026. Karikó is a Hungarian-American biochemist and the 2023 winner of...

Katalin Karikó will be @jhu.edu's 2026 commencement speaker. Excellent choice!

www.jhunewsletter.com/article/2026...

2 weeks ago 37 7 3 0

The civilization that would die if such threats were carried out is our own.

2 weeks ago 217 60 6 4
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For almost a century generations of scholars and thinkers have tried to understand why the Germans sleepwalked into disaster. Future generations will focus on a different case.

2 weeks ago 997 338 1 29
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Massive budget cuts for US science proposed again by Trump administration Budget proposal would also curb federal payments for scientific publishing.

The administration's budget request would cut research funding for the National Science Foundation and the Environmental Protection Agency by more than 50%.

It's hard to imagine an external enemy causing more long-term damage to this country.

www.nature.com/articles/d41...

2 weeks ago 389 144 16 8

Same to you, Rob!

2 weeks ago 1 0 0 0
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A run-length-compressed skiplist data structure for dynamic GBWTs supports time and space efficient pangenome operations over syncmers
doi.org/10.64898/202...

3 weeks ago 17 5 0 0

While the situation is grim at NIH, it's closer to catastrophic at NSF. They're just not able to move any money out the door. It appears OMB has them on lockdown. www.science.org/content/arti....

3 weeks ago 366 250 7 15
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Postdoktor i Beräkningsbiologi Matematiska institutionen består av cirka 120 forskare, lärare och administrativ personal och är organiserad i tre huvudsakliga avdelningar: Matematik, Matematisk statistik och Beräkningsmatematik

𝗣𝗼𝘀𝘁𝗱𝗼𝗰 𝗮𝗻𝗱 𝗣𝗵𝗗 𝗽𝗼𝘀𝗶𝘁𝗶𝗼𝗻𝘀 𝗶𝗻 𝗖𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗚𝗲𝗻𝗼𝗺𝗶𝗰𝘀 / 𝗔𝗹𝗴𝗼𝗿𝗶𝘁𝗵𝗺𝗶𝗰 𝗕𝗶𝗼𝗶𝗻𝗳𝗼𝗿𝗺𝗮𝘁𝗶𝗰𝘀

I am currently recruiting for both:

🔹 Postdoc position
su.varbi.com/what:job/job...

🔹 PhD position
su.varbi.com/en/what:job/...

Please share with anyone who might be interested!

1 month ago 18 19 2 1
Congratulations! Vikram Shivakumar successfully defended his dissertation “Scalable Sequence Analysis Using Compressed Pangenome Indexing” under the guidance of advisor Ben Langmead. Vikram plans to pursue a joint postdoctoral fellowship at the European Bioinformatics Institute, the Wellcome Sanger Institute, and the University of Cambridge. We in the department are extremely proud of our students who have successfully completed their PhD. Congratulations on this achievement and best wishes as you begin an exciting new phase of life!

Congratulations! Vikram Shivakumar successfully defended his dissertation “Scalable Sequence Analysis Using Compressed Pangenome Indexing” under the guidance of advisor Ben Langmead. Vikram plans to pursue a joint postdoctoral fellowship at the European Bioinformatics Institute, the Wellcome Sanger Institute, and the University of Cambridge. We in the department are extremely proud of our students who have successfully completed their PhD. Congratulations on this achievement and best wishes as you begin an exciting new phase of life!

Congratulations, @vikramshivakumar.bsky.social!

1 month ago 15 5 0 1

Amazing opportunity. Best of luck, Gamze! Perhaps I'll see you at Genome Informatics in December?

1 month ago 1 0 1 0

Here is the "effective payline" for each institute, estimated (by Claude) as the percentile where one can expect 80% probability of funding from a logistic regression fit. The effective payline has gone from a historic ~12% to 6% in 2025.

1 month ago 97 69 15 14

Very nice post, and this is very lovely work

1 month ago 1 0 1 0
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National Institutes of Health faces leadership vacuum as director positions sit open More than half of the NIH's institutes and centers don’t have permanent directors, giving the Trump administration an unusual opportunity to reshape the agency. The latest departure came on Friday.

They won’t stop until the National Institutes of Health is a hollowed out RFK Jr. echo chamber and revenue generation machine for snake oil peddlers.

2 months ago 277 103 12 4
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Trump official overruled FDA scientists to reject Moderna's flu shot FDA's top vaccine regulator, Vinay Prasad, is known for overruling scientists.

Moderna is at least the ninth company to have received a surprise rejection from Vinay Prasad and his team.

2 months ago 131 82 10 18
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A Speech Every Democrat Should Watch Jon Ossoff lays out a message that can work for everyone in the party.

If you were online last weekend, you probably caught some clips from Jon Ossoff’s speech. It’s worth watching the whole thing because it’s an object lesson in how Democrats should communicate in the upcoming midterms. messagebox.substack.com/p/a-speech-e...

2 months ago 108 25 1 3
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Prasad overruled FDA staff to reject Moderna's flu vaccine application The rejection is the latest instance of Vinay Prasad overruling career FDA scientists to place vaccines under harsher scrutiny.

The flu and pneumonia kill over 45,000 people a year. Moderna developed a new mRNA flu vaccine for people 50 and older--who are most at risk. Prasad, unilaterally, against the recommendation of experts within the agency, denied Moderna's appplication. www.statnews.com/2026/02/11/m...

2 months ago 619 329 20 35
Freeman Hrabowski III, the President Emeritus from the University of Maryland Baltimore County, giving a TED talk.

Freeman Hrabowski III, the President Emeritus from the University of Maryland Baltimore County, giving a TED talk.

This is a powerful message from Freeman Hrabowski.

🧵

1/12

2 months ago 55 40 1 3
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The Biology of Genomes Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.

Reminder that the abstract deadline for the Biology of Genomes meeting at CSHL is on Feb 13! We have a fantastic lineup of keynote speakers (Janet Kelso and Jonathan Pritchard) and session chairs. Submit your best science to this exciting and engaged meeting!
meetings.cshl.edu/meetings.asp...

2 months ago 19 11 0 2

Super thread, thank you Ragnar. I told my lab I would explain suffixient sets in a meeting this week and I'm going to start by just walking through your thread 🙏

2 months ago 2 0 1 0