Systematic reviews of qualitative evidence. The JBI logo is displayed against blue background with an abstract suggestion of ripples. The ripples evoke the JBI logo. (The JBI logo depicts a pebble (‘evidence’) dropping into water, symbolising the ripple effect of positive change driven by evidence.)

Qualitative systematic reviews give voice to patients, clinicians. It's not just about numbers, but understanding the 'whys' behind health-related decisions.

Find methodological guidance in the JBI Manual for Evidence Synthesis at https://ow.ly/q5Bz50YrFg2 #JBImethodology

We have a miraculous anti-aging vaccine. Why aren’t more people getting it? Research has found that a routine vaccine slows aging and cut dementia risk.

Research has found that a routine vaccine slows aging and cut dementia risk. www.vox.com/health/47776...

How to improve vaccine uptake: a huge study offers clues Nature - An analysis of more than one million people in the UK found that two-thirds of people who were vaccine-hesitant during the COVID-19 pandemic went on to get vaccinated.

An analysis of more than one million people in the UK found that two-thirds of people who were vaccine-hesitant during the COVID-19 pandemic went on to get vaccinated

go.nature.com/4sKfBFk

The NIH has lost its scientific integrity. So we left “We can no longer lend our credibility to an organization that has lost its integrity,” write four scientists and administrators who recently resigned from the NIH.

An important read on the loss of credibility of the The National Institutes of Health under the Trump regime.

www.statnews.com/2026/01/10/n...

Via @statnews.com

#evidencebasedmedicine #EBM #research #decisionmaking #NIH #medicine #publichealth

Understanding Canada's drug approval and reimbursement pathway just got a whole lot easier with the release of this new online explainer from the CDA-AMC.

www.cda-amc.ca/drug-systems...

#HTA #evidence #HEOR #systematicreviews #regulatory #CDAAMC

Day 2️⃣ of the @nihr-io.bsky.social Futures, Foresight & Horizon Scanning conference has been absolutely jam-packed with great science!

We kicked off with a thought-provoking keynote, followed a great range of talks - from new start-up projects to horizon scanning in the wearables space.

#FFHSC

A fantastic first day today at the @nihr-io.bsky.social Futures, Foresight & Horizon Scanning conference!

Really interesting range of talks, and lots of engaging, in-depth insights and methodologies on display.

Can’t wait for day two!

#FFHSC

Very excited to be off to the @nihr-io.bsky.social Futures, Foresight & Horizon Scanning conference on 19th-20th November!

Looking forward to lots of great talks - the lightning sessions especially sound fantastic ⚡️⚡️⚡️

Please do shout if you are going along - would be great to say hello 👋

#FFHSC25

A new #systematicreview and #networkmetaanalysis shows that antidepressants differ markedly in their physiological effects, with substantial differences in parameters such as weight, cholesterol, heart rate, blood pressure

www.thelancet.com/journals/lan...

@thelancet.com

#OA #depression #NMA

Happy Ada Lovelace Day! Enjoy this annual international celebration of the achievements of women in science, technology, engineering and maths (STEM).

findingada.com

H/T @hildabast.bsky.social for the share in her excellent newsletter

“The most important thing about #AI isn't its technical capabilities or limitations. The most important thing is the investor story and the ensuing mania that has teed up an economical catastrophe that will harm hundreds of millions or even billions of people.”

pluralistic.net/2025/09/27/e...

A microsimulation model based on healthcare pathways to estimate the impact of COVID-19 pandemic–induced delays on breast cancer mortality This study aimed to develop a microsimulation model to estimate the impact of a care disruption during the COVID-19 pandemic on breast cancer mortality using an administrative database.

A microsimulation model to estimate the impact of care disruption during the COVID-19 pandemic on breast cancer mortality using an administrative database.

www.jclinepi.com/article/S089...

Via @jclinepi.bsky.social

ACOG reaffirms that acetaminophen is safe for managing pain and fever during pregnancy. No reputable studies support suggestions like those in HHS’s recent announcement linking acetaminophen use in pregnancy to autism; in fact, high-quality studies show no such risk. https://bit.ly/47Wxc59

🚨Emerging Point-of-Care Testing in Genomics

Exploring the development pipeline of genomic POCTs designed to identify variations in the genome & epigenome, supporting diagnosis, prognosis & treatment decisions across clinical areas👉 ow.ly/UB2R50WQcvo @newcastleuni.bsky.social @nihr.bsky.social

Including conference abstracts rarely changed systematic review conclusions: a case study from a living network meta-analysis of COVID-19 treatments Including conference abstracts (CAs) in systematic reviews (SRs) helps reduce publication bias but raises concerns about reporting quality and reliability. While discrepancies with full publications a...

The contribution of conference abstracts in #systematicreviews - "Their inclusion changed the effect estimate in 55.6% and imprecision in 16% of cases when using MIDs. In a few instances, CAs also influenced RoB and inconsistency assessments."

www.jclinepi.com/article/S089...

@jclinepi.bsky.social

Exclusive: RFK Jr. and the White House buried a major study on alcohol and cancer. Here’s what it shows. Kennedy wants to “Make America Healthy Again” — but doesn’t want you to see a report that could do just that.

Most Americans still don’t know that #alcohol can cause #cancer — and the alcohol industry and Trump are working hard to make sure it stays that way by discrediting and burying a new report that offers new evidence of the link between drinking alcohol and dying www.vox.com/health/46008... @vox.com

Quote by Seth Berkley on a black background, stating: "…one of humanity's most dramatic successes has been the application of science to understand and then decisively intervene to improve...harrowing conditions."

In a new #ScienceExpertVoices article, Seth Berkley unravels the arc of vaccine progress. https://scim.ag/3VrCDBx

Most air cleaning devices have not been tested on people − and little is known about their potential harms, new study finds Manufacturers often make bold claims about how well these technologies work. Better testing would allow consumers and institutions to pick the most effective ones.

Most air cleaning devices have not been tested on people, and little is known about their potential harms. Professors of medicine and public health explain:

New #research that could help clinical trials avoid early termination.

Identifying predictors of early trial termination: a meta-epidemiological study utilising elements of the research ethics committee evaluation.

www.jclinepi.com/article/S089...

Via @jclinepi.bsky.social

Why are indexers unable to see that peer review can be more than a thumbs up or a thumbs down? | DORA Journals and peer review are unlikely to change for the better if the companies that operate scientific indexes and citation databases continue to stifle innovation. At eLife we believe that the conte...

A really thought-provoking article from @elife.bsky.social about manuscript publication, peer review and who acts as the gatekeepers of publishing: “why are indexers unable to see that peer review can be more than a thumbs up or a thumbs down?” sfdora.org/2025/07/30/s... H/T @hildabast.bsky.social

Being hit by an SUV increases the likelihood of death or serious injury | LSHTM The likelihood of a pedestrian or cyclist being fatally injured is 44% higher if they are hit by a sports utility vehicle (SUV) or light truck vehicle (LTV) compared with smaller passenger cars, new

Does this infographic possibly miss out the fact that Americans also tend to drive much larger SUVs, which increases the likelihood of pedestrian fatalities quite substantially, especially for children? www.lshtm.ac.uk/newsevents/n...

This is figure 2, which shows physiological pathways underlying the association between ultra-processed dietary patterns and obesity.

A Review in Nature Reviews Endocrinology assesses the role of ultra-processed foods in obesity, examining the epidemiological evidence, biological mechanisms and implications for policymakers. go.nature.com/44zGHoO 🍎📃 #medsky 🧪

How human eggs stay fresh for decades In human beings, egg cells need to survive for about five decades, much longer than most other cell types – and they may achieve this unusually long lifespan by slowing down their natural cell processes

In human beings, egg cells need to survive for about five decades, much longer than most other cell types – and they may achieve this unusually long lifespan by slowing down their natural cell processes.

#SupportOLSPub - every vote counts
The first giant steps have been taken, the OLSPub application has been submitted. For all those who, as researchers, information specialists or simply as people, would like to position themselves, everyone can leave a signature here.
blog.zbmed.de/olspub-support

The MAHA report critique, by @hiltzikm.bsky.social
www.latimes.com/business/sto...
And the Trojan horse, by @drjengunter.bsky.social
vajenda.substack.com/p/hijacking-...

The remarkable benefit of exercise was just extended to improved survival after cancer in a randomized trial
@nejm.org
nejm.org/doi/full/10....

Endothelial Dysfunction and Chronic Cannabis Use This cross-sectional study aims to determine whether cannabis use is associated with vascular endothelial function.

In the wake of several countries legalising #marijuana, questions remain about the drug's long-term #health effects. A new study has found that people who smoke weed or use edibles do worse on measures of vascular health that predict cardiovascular risk.

jamanetwork.com/journals/jam...

@jama.com

A scoping review of carbon emissions associated with clinical trials finds that several trial activities, including travel and meetings, trial facilities, and sample & lab activities, are consistently carbon heavy.

www.jclinepi.com/article/S089...

@jclinepi.bsky.social

#scopingreview #openaccess

Brand new SPIRIT and CONSORT #reporting #guidelines are out now!

🎯 CONSORT 2025 for reporting RCTs now has a 30-item checklist

🎯 SPIRIT 2025 for reporting trial protocols now has a 34-item checklist

www.jclinepi.com/article/S089...

@jclinepi.bsky.social

#SPIRIT #CONSORT #RCTs #protocols