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Posts by Doug Epstein

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A. James Hudspeth, Who Unlocked Mysteries Behind Hearing, Dies at 79

www.nytimes.com/2025/09/05/s...

7 months ago 2 0 0 0
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Penn Genetics is excited to host Harmit Malik who will be giving the Bernard Cohen Memorial Lecture today.

11 months ago 18 3 0 0
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Baby Is Healed With World’s First Personalized Gene-Editing Treatment

www.nytimes.com/2025/05/15/h...

11 months ago 5 0 0 0
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Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...

www.cnn.com/2025/04/09/h...

1 year ago 1 0 0 0
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The Holocaust Story I Said I Wouldn’t Write For years, my friend’s father asked me to recount his childhood escape from the Nazis. Why did it take me this long?

Jehuda Lindenblatt wanted the writer Taffy Brodesser-Akner to tell his story of survival for years. In finally doing so, she reckons with how many people in her generation push away thoughts of the Holocaust to cope, only to find themselves dealing with them anyway.

1 year ago 261 59 6 4
Mark Carney is wearing a dark blue suit, white shirt and blue tie. A Canadian flag is pinned to his lapel. A headline reads: "Mark Carney to Be the Next Prime Minister of Canada." Photo by Andrej Ivanov/Agence France-Presse — Getty Images

Mark Carney is wearing a dark blue suit, white shirt and blue tie. A Canadian flag is pinned to his lapel. A headline reads: "Mark Carney to Be the Next Prime Minister of Canada." Photo by Andrej Ivanov/Agence France-Presse — Getty Images

Breaking News: Mark Carney, a banker, will replace Justin Trudeau as Canada’s Liberal Party leader and the country’s prime minister. The party chose him to take on President Trump amid a generational crisis in Canada’s relationship with the U.S. www.nytimes.com/2025/03/09/w...

1 year ago 2681 395 177 58
Facilities and Administrative (F&A) Costs Explainer
Facilities and Administrative (F&A) Costs Explainer YouTube video by Association of American Universities

Understanding the real costs of research

1 year ago 3 0 2 0
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Philadelphia Stand Up For Science! #standupforscience2025

Friday, March 7 · 11am - 1pm
Philadelphia City Hall

standupforscience2025.org

1 year ago 16 7 0 0
various cochlear implant wearers

various cochlear implant wearers

Happy International Cochlear Implant Day! Over the years we’ve shared so so many stories from families and individuals who are able to benefit from this life-changing technology (which we helped fund in the 1970s and '80s)! Cheers to these miracle ears! #cochlearimplants #keeplistening

1 year ago 2 2 0 0

We did it. Fly Eagles Fly🦅🦅🦅

1 year ago 12 1 0 0
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Ear Science Institute Australia Leads Biobank Initiative to Advance Genetic Therapies and Personalized Treatment for Hearing Loss | Hearing Health & Technology Matters Ear Science Institute Australia will develop a WA-headquartered Australasian first biobank to advance genetic therapies for childhood and adult hearing loss. The Australasian Hearing Registry and Biob...

"Pioneering gene therapy offers hope for restoring hearing in patients with genetic hearing loss. With 155 genes linked to hearing loss and new discoveries every day, navigating this complex genetic landscape presents a monumental challenge.” From: hearinghealthmatters.org/hearing-news...

1 year ago 1 1 0 0
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Casey Brown Lecture Series - YouTube

Our mentor Casey Brown, apart from being an extraordinary scientist, was a brilliant teacher who loved everything genetics. In his honor, some of the world's leading experts came together to create the 'Casey Brown Lecture Series' on human genetics 1/ shorturl.at/eCm7S

1 year ago 48 32 1 3
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LDB1 establishes multi-enhancer networks to regulate gene expression - PubMed How specific enhancer-promoter pairing is established remains mostly unclear. Besides the CTCF/cohesin machinery, few nuclear factors have been studied for a direct role in physically connecting…

New paper alert! @cambupenn G&E student @ngaboreden in the @blobellab on: LDB1 establishes multi-enhancer networks to regulate gene expression

1 year ago 4 1 0 0
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How can some vertebrates naturally recover from deafness?

In work in PNAS, Tuo Shi finds that enhancers for sensory genes remain open but silent in sister cells of zebrafish and lizards, allowing these to make new inner ear sensory hair cells upon damage. www.pnas.org/doi/10.1073/...

1 year ago 58 18 3 3
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This is going to save hospitals a lot of money !

www.pennmedicine.org/news/news-re...

1 year ago 47965 6682 1805 391
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medical scientist training program (MSTP)

1 year ago 32 6 0 0
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a cartoon of homer simpson holding a card ALT: a cartoon of homer simpson holding a card

Following a suggestion from @benecal.bsky.social I will refer to these threads as "skeetorials" and will use this gif logo.

Today's skeetorial is about the NIH Director's New Innovator Award with three different heroes (all in government).

1/n

1 year ago 133 41 10 16
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Multiple allelic configurations govern long-range Shh enhancer-promoter communication in the embryonic forebrain Harke et al. use sequential DNA-FISH to achieve single-allele resolution of the Sonic hedgehog (Shh) regulatory domain in the mouse forebrain. They show that multiple allelic configurations occur inde...

Our study with @ericjoyce.bsky.social led by Jailynn Harke is out. We show that allelic configurations at the Shh locus are predominately compact in the mouse forebrain, and that long range E-P interactions rely on transcription dependent and independent mechanisms. www.cell.com/molecular-ce...

1 year ago 28 11 2 2
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