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Posts by NC3Rs

🏆 The 3Rs Prize award consists of a £28k Prize grant and a £2k personal award to further your work and its impact.

✍️ Do you have a paper that fits the remit? Complete the short application form by Monday 4 May 2026.

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The international Prize is supported by GSK and recognises innovative and exceptional work that has delivered, or could have, major 3Rs benefits on the use of animals in research.

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International 3Rs Prize

We invite researchers from around the world to showcase their 3Rs achievements on the global stage by applying for our annual NC3Rs 3Rs Prize: nc3rs.org.uk/internationa...

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Banner shows the pint of science logo and the dates for the 2026 NC3Rs sponsored events: Newcastle 18 May, Bristol 19 May, London 20 May.

Banner shows the pint of science logo and the dates for the 2026 NC3Rs sponsored events: Newcastle 18 May, Bristol 19 May, London 20 May.

We are thrilled to be returning to @pintofscience.uk for our twelfth year as festival sponsors! Join us in Newcastle, Bristol and London as NC3Rs-funded scientists showcase innovations in replacement approaches and explore the future of alternatives to animals. 🎟️ pintofscience.co.uk/sponsor/nc3rs/

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Welfare webinar: Habituation of minipigs, non-human primates and dogs for procedures in toxicology studies Practical guidance to reduce stress during inhalation studies, blood sampling and ophthalmological exams.

Register for our upcoming welfare webinar focusing on habituating dogs, minipigs and non-human primates to procedures in toxicology studies to refine their use in regulatory safety assessment: nc3rs.org.uk/events/welfa...

📅 Thursday 14 May, 12.30 – 13.30 (GMT)
📜 Certificates of attendance available

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SIRF-UP, Sex Inclusive Research Framework - Understanding and Practice, from EU-SABV COST Action. Icons representing different steps of the SIRF-UP initiative: Pre-engagement survey, support pack, apply the SIRF, post-engagement survey and stay involved.

SIRF-UP, Sex Inclusive Research Framework - Understanding and Practice, from EU-SABV COST Action. Icons representing different steps of the SIRF-UP initiative: Pre-engagement survey, support pack, apply the SIRF, post-engagement survey and stay involved.

If you are involved in an ethical review body anywhere in the world (including AWERBs, IACUCs or Animal Welfare Committees), you can get involved in SIRF-UP. Answer a short survey, receive a support pack to apply the Sex Inclusive Research Framework and share your feedback: sabv.eu/article/sirf...

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SIRF-UP is an @eu-sabv.bsky.social COST Action initiative to support ethical review bodies assess sex-inclusivity in animal research. Using female and male animals should be the default to reduce the total number of animals used and produce results that are generalisable to the whole population.

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Bundles of skeletal muscle fibres representing the STRATIS CRACK IT Challenge, next to the CRACK IT logo. Text reads: Webinar recording available.

Bundles of skeletal muscle fibres representing the STRATIS CRACK IT Challenge, next to the CRACK IT logo. Text reads: Webinar recording available.

Webinar recording available: nc3rs.org.uk/3rs-resource...
Myomaker Bio share an in vitro vascularised and innervated skeletal muscle model developed through the NC3Rs STRATIS CRACK IT Challenge to improve translation in musculoskeletal research and replace some animals in preclinical drug screening.

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The NC3Rs Technology Partn3Ring webinar series on new approach methodologies, represented by icons of organ-on-chip, organoid, in vitro and in silico models

The NC3Rs Technology Partn3Ring webinar series on new approach methodologies, represented by icons of organ-on-chip, organoid, in vitro and in silico models

Are you interested in collaborating on the latest replacement technologies for chemical or drug testing? Register for the first two sessions in our upcoming Technology Partn3Ring webinar series on new approach methodologies: nc3rs.org.uk/crackit/nams...

📅 22 April and 6 May, 14.00 – 15.15 (BST)

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Bridging the gap: New funding for academic-industry partnerships between NC3Rs Network members In partnership with the BBSRC we have awarded over £200k to strengthen cross-sector collaborations that improve the relevance and real-world impact of 3Rs models and technologies.

We have awarded over £200k across nine teams through a new joint funding initiative with the BBSRC: nc3rs.org.uk/news/bridgin...

Our Business Interaction Voucher awards support cross-sector collaborations to enhance the biological relevance of 3Rs models and ensure they are fit for use in industry.

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NC3Rs staff members typing at their laptops during a ‘I’m a scientist’ school chat session.

NC3Rs staff members typing at their laptops during a ‘I’m a scientist’ school chat session.

To celebrate British Science Week, NC3Rs staff took part in eight @imascientist.org.uk online chats last week, meeting around 150 school students. It is always great to see how curious young people are about the ways that scientists are replacing, reducing and refining the use of animals!

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⏳ Applications close this Friday, 6 March.

If you are interested in becoming an Antibody Champion, complete the short (~10 minute) online application today to tell us why you would make a great champion and your current experiences of working with antibodies and promoting best scientific practice.

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Bundles of skeletal muscle fibres. On the right is the CRACK IT logo. Text reads: Webinar, Thursday 5 March.

Bundles of skeletal muscle fibres. On the right is the CRACK IT logo. Text reads: Webinar, Thursday 5 March.

🧫 Human in vitro tissue models of musculoskeletal disease and injury - nc3rs.org.uk/events/human...
📅 Thursday 5 March, 14.00 – 15.00 (GMT)

Myomaker Bio will share replacement approaches for preclinical drug discovery, developed through the NC3Rs STRATIS CRACK IT Challenge.

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📊 Experimental Design Assistant (EDA) virtual workshop - nc3rs.org.uk/events/exper...
📅 Wednesday 4 March, 16.00 – 18.00 (GMT)
NOTE: Registration closes 24 hours before

Join @drejpearl.bsky.social for an interactive session on the EDA software to help researchers design robust in vivo experiments.

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A 'virtual dog' with interconnected nodes representing computer modelling, within the outline of a dog. On the right are the NC3Rs and VICT3R logos.

A 'virtual dog' with interconnected nodes representing computer modelling, within the outline of a dog. On the right are the NC3Rs and VICT3R logos.

🌐 Virtual Second Species: Data driven and mechanistic modelling of the dog – nc3rs.org.uk/events/virtu...
📅 Tuesday 3 March, 13.00 – 14.00 (GMT)

We are teaming up with @ihi-vict3r.bsky.social to showcase the 'Virtual Dog' from the NC3Rs CRACK IT Challenge to minimise use of dogs in safety studies.

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Collage of graphics representing upcoming NC3Rs online events: A virtual dog, an Experimental Design Assistant diagram, and skeletal muscle fibres.

Collage of graphics representing upcoming NC3Rs online events: A virtual dog, an Experimental Design Assistant diagram, and skeletal muscle fibres.

Register for upcoming 3Rs events from the NC3Rs and others taking place online this week: nc3rs.org.uk/events

⬇️ Details in the thread below.

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Register for our next virtual workshop on using the Experimental Design Assistant (EDA): nc3rs.org.uk/events/exper...

📅 Wednesday 4 March, 16.00 – 18.00 (GMT)
⏰ Registration closes: Tuesday 3 March
📜 Certificates of attendance available for one CPD point

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Delegates in discussion at a scientific meeting.

Delegates in discussion at a scientific meeting.

To support delivery of the UK Government’s alternatives strategy, we are working with @innovateuk.bsky.social on a Contracts for Innovation competition, with £2M available for non-animal approaches in pharmacokinetic prediction and cardiovascular safety.

Learn more: nc3rs.org.uk/news/working...

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Bundles of skeletal muscle fibres next to the CRACK IT logo. Text reads: Webinar, Thursday 5 March.

Bundles of skeletal muscle fibres next to the CRACK IT logo. Text reads: Webinar, Thursday 5 March.

📢 Webinar – Human in vitro tissue models of musculoskeletal disease and injury: nc3rs.org.uk/events/human...

📅 Thursday 5 March, 14.00 (GMT)

Learn more about an in vitro vascularised and innervated skeletal muscle model of traumatic injury, developed through our STRATIS CRACK IT Challenge.

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An outline of a dog, the NC3Rs and VICT3R logos.

An outline of a dog, the NC3Rs and VICT3R logos.

Virtual Second Species: Data driven and mechanistic modelling of the dog
📅 3 March, 13.00 (GMT)/14.00 (CET)
👉 nc3rs.org.uk/events/virtu...

In their next ‘Virtually Speaking’ webinar, VICT3R @ihi-vict3r.bsky.social are showcasing the ‘Virtual Dog’ being developed through an NC3Rs CRACK IT Challenge.

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Many medicines entering clinical trials fail because pre-clinical testing does not accurately predict effects in humans.

A key reason? A gap between some 'pre-clinical models' and industry needs.

A new ABPI/@nc3rs.bsky.social review sets out how to close this gap. abpi.org.uk/publications...

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A landscape review of human relevant pre-clinical model development in the UK New report by the Association of the British Pharmaceutical Industry (ABPI) and the NC3Rs examines the UK's capabilities in developing human relevant pre-clinical models for medicine development.

We are delighted to publish a report with @abpi.bsky.social that examines the UK landscape in human relevant in vitro models. It will help inform wider policy, funding and infrastructure requirements to accelerate translation and deliver benefits for pharmaceutical R&D. nc3rs.org.uk/news/landsca...

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Early career researchers in discussion at a scientific training session.

Early career researchers in discussion at a scientific training session.

We are working with @oga-community.bsky.social to recruit a cohort of early career researchers who will drive the validation and use of better antibodies. Are you our next Antibody Champion?

More details, eligibility and application process: nc3rs.org.uk/news/antibod...

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Registration deadline: If you would like to join us on Thursday (5 February) for our interactive webinar on commercialising NAMs technologies, please register by 13.00 on Wednesday.

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Delegates in discussion at a scientific meeting.

Delegates in discussion at a scientific meeting.

📢 Delivering the alternatives strategy – Pharmacokinetics and cardiac safety: nc3rs.org.uk/events/nc3rs...

Join us and @innovateuk.bsky.social to explore how research collaboration and innovation can deliver government targets to replace animal use in drug development.

📅 10 March, Central London

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Data-driven design of fish cell line-based reproductive toxicity assays Outcomes from the SAFE CRACK IT Challenge to replace fish studies in chemical safety screening and environmental risk assessment.

Webinar recording – Replacing fish studies in chemical safety screening and regulatory environmental risk assessment: nc3rs.org.uk/3rs-resource...

Learn more about fish cell line-based reproductive toxicity assays developed by aQuaTox Solutions GmbH and Eawag through our SAFE CRACK IT Challenge.

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The 3Rs Collaborative logo and an icon representing artificial intelligence 3Rs approaches. Text reads: AI survey.

The 3Rs Collaborative logo and an icon representing artificial intelligence 3Rs approaches. Text reads: AI survey.

Do you use artificial intelligence to improve toxicity prediction, support regulatory science or reduce the reliance on animal use in safety assessment?

Share your work and insights with the 3Rs Collaborative AI Initiative: forms.cloud.microsoft/pages/respon...

⏰ Survey closes: 21 February.

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Welfare webinars Practical welfare refinements to support positive change in day-to-day practice.

📢 Due to unforeseen circumstances this webinar has been postponed.

If you have already registered, you will receive an email with further information. Registration will re-open when a new date is confirmed.

Previous welfare webinar recordings are available online: nc3rs.org.uk/3rs-resource...

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📢 Due to unforeseen circumstances this webinar has been postponed.

If you have already registered, you will receive an email with further information. Registration will re-open when a new date is confirmed.

Previous welfare webinar recordings are available online: nc3rs.org.uk/3rs-resource...

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Icons representing new approach methodologies in toxicology and regulatory safety assessment, including a laboratory flask, a computer model of a chemical structure and an environmental scene.

Icons representing new approach methodologies in toxicology and regulatory safety assessment, including a laboratory flask, a computer model of a chemical structure and an environmental scene.

Join the conversation about commercialising new approach methodologies (NAMs) for safety assessment in an interactive webinar featuring a live Q&A with expert method developers at our next NAMs Network event.

📅 5 February, 13.00 (GMT)
⏰ Registration closes: 4 February
👉 nc3rs.org.uk/events/nc3rs...

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