Excited to share a new review by @kocherlab.bsky.social and me:

Nature-inspired neuroscience

We discuss diverse sensory systems and behaviors across the animal kingdom and argue for their integration into neuroscience. New tools in diverse systems are making this possible ✨

tinyurl.com/y5y9du27

Light-inducible FLPase reconstitution enables temporal control of gene expression in Drosophila melanogaster
#Drosophila

Congrats! Yeah

Spatial, temporal and Notch determination of terminal selector expression controls neuronal cell fate in the Drosophila optic lobe - Nature Neuroscience The authors characterized the spatial origin of Drosophila medulla neurons, completing their previous characterization of the temporal and Notch origins of these neurons and allowing them to correlate...

Félix Simon's paper is out in its final form 😍
When we got into (extreme) detail in the temporal and spatial patterning of neuroblasts, Félix asked a simple question "sure, but how does this translate into neuronal cell fate?". www.nature.com/articles/s41...

News News

Great news from the lab - we’ve been awarded a MIRA (R35)!

This grant provides 5-year support for our research program. We are very grateful to NIGMS/ #NIH for supporting our research. We will be hiring a research technician and a postdoc.

fernandez.lab.indiana.edu/news/index.h...

The neural mechanisms supporting the rise and fall of maternal aggression - Nature In mice, female aggression is governed by an amygdala–to–medial hypothalamus circuit that is strengthened during pregnancy and is dynamically amplified by oxytocin during lactation.

What has changed in mama bear brain (well, actually mice) to make her risk her life to attack a potential threat and protect her young? Oxytocin is the key! Happy to share our new study led by two awesome postdocs: Takashi Yamaguchi and Rongzhen Yan.
www.nature.com/articles/s41...

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis - Nature Metabolism In vivo regulation of neuronal lipid droplet formation mediates whole-body energy homeostasis in a sex-specific manner in Drosophila and mice.

Beyond delighted to share our amazing collaboration with Thierry Alquier's lab @alquierthierry.bsky.social on a conserved role for neuronal lipid droplets in regulating energy homeostasis in vivo led by Celena Cherian, Romane Manceau, Danie Majeur, and Colin Miller www.nature.com/articles/s42... /1

🎉New paper out from the lab, led by @baptistepiqueret.bsky.social: ant larvae chemically suppress the reproduction of their caregivers. bit.ly/4t8uZLG
An example of how social interactions are regulated at the molecular level. The work was made possible by the unique environment @mpi-ce.bsky.social

New article with @oudietted.bsky.social and the @dreamteamicm.bsky.social

Dream-like mental states can occur during wakefulness

Published now in @cp-cellreports.bsky.social

www.cell.com/cell-reports...

Congrats to Nicolas Decat!

Thank you! :)

We’re recruiting!

Exciting opportunities in our lab supported by a
@wellcometrust.bsky.social Discovery Award.

• Postdoctoral researchers
• Research assistant/PhD students

Join us to study how neural circuits drive decision-making.

Deadline 26/04

Learn more and Apply here: rezavallab.org

Are you a computational scientist? Within 7 years of your PhD? Come join us at Lund University! We have two new positions as assistant professor! Deadline: 25th of May. The advert is broad, but this is your chance to push computational neuroscience in a fantastic place!
lu.varbi.com/en/what:job/...

@jlarsch.bsky.social and I are organising the 2026 CIG Symposium on June 11-12 in Lausanne on "Information transfer: from genes to behaviour", featuring an eclectic set of brilliant scientists. Details and registration here (abstracts by May 1, registration by June 1):

www.unil.ch/fbm/en/home/...

Proud to have supported James on this great project

its an example of one of my favourite types of computational/theoretical neuroscience studies:

first identifies an underappreciated but severe problem for current brain theory

then goes and uses maths and clever sims to figure out the solution 😀

🧵 New preprint led by @bingbrunton.bsky.social, @elliottabe.bsky.social, @lawrencehu.bsky.social

We gave a worm brain control of a fly body and it walked

What did we learn? Nothing, other than deep reinforcement learning is effective

We call it the digital sphinx

www.biorxiv.org/content/10.6...

Another paper from our awesome lab out today @nature.com. Led by 🌟 PD Jihye Yeon with fantastic collaborators. We show how an ionotropic receptor (related to insect sensory IRs) in a single pharyngeal enteric neuron senses ingested salts and protects the worm from high salt stress.
rdcu.be/fbd4a

Top: Putative engram cells were identified as GFP (cFos) signals in the indicated mushroom body cell body region dorsal to the calyx 24 hours after spaced training of UAS-mCD8-GFP; kayak-Gal4/Tubp-Gal80ts flies. pERK signals observed after odor exposure 24 hours after training were used to identify cells activated during memory recall tests. Bottom: Schematic for optogenetic reactivation of engram cells. Channelrhodopsin-YFP (ChR2-YFP) was expressed in putative engram cells using the same strategy of expressing GFP above. Twenty-four hours after spaced training, flies were tested for their preference of blue light (which activates channelrhodopsin) vs. green light.

Long-term memories become imprecise as animals age, but what are the neural mechanisms? This study shows that increased #dopamine signaling during #memory consolidation causes memory #EngramCells to respond to inappropriate cues, inducing memory generalization @plosbiology.org 🧪 plos.io/4v62VtD

🎓 Calling PhD students & early-career postdoctoral fellows!
Planning to attend a #neuroscience training course between 1 July – 31 Dec 2026? IBRO is offering training #grants to support your participation.

Discover the eligibility criteria, which costs are covered & more👇
https://ow.ly/NFkf50YAvpp

Come join us! We're recruiting 3 new academic posts in the School of Biology, University of Leeds, closing 23/04/26.

Assoc Prof Plant Science tinyurl.com/4x48jc78
Assoc Prof Animal Biology tinyurl.com/2s4sk85s
Lecturer in Ecology, Zoology, Biodiversity or Ecosystem Management: tinyurl.com/39dwp47j

📢 The BCCN Berlin is hiring a Network Outreach Coordinator!

Check out their page for more information 👉 bit.ly/3NDunhP

#BernsteinNetwork #CompNeuro #Neuroskyence

Many thanks to @klaus-tschira-stiftung.de and @gso-forresearchers.bsky.social for this wonderful opportunity to study the mechanisms underlying naturalistic decision processes in the context of foraging behavior!
We’ll also soon have openings for PhD students, stay tuned!

Low-intensity focused ultrasound to human amygdala reveals a causal role in ambiguous emotion processing and alters local and network activity The amygdala shows abnormal metabolism in depression, a disorder marked by altered emotion, motivation, and learning. Yet its causal role in these pro…

Very happy our first paper using ultrasound stimulation (TUS) to stimulate the human amygdala (BLA) got out in @cp-neuron.bsky.social today! 🎉🥳🔊Great FUN with co-first authors @mirunmigyu.bsky.social @lilweb.bsky.social in @mkflugge.bsky.social 's lab!
www.sciencedirect.com/science/arti...

Dorsoventral hippocampus neural assemblies reactivate during sleep following an aversive experience - Nature Neuroscience Synchronization of sharp-wave ripples across the dorsoventral hippocampus during sleep supports coordinated reactivation that represents negative experiences more faithfully than positive ones.

Our paper is out today!!! (not an April fool's day joke) Congrats to authors @azulsilva.bsky.social, @belalima-paiva.bsky.social, Ele Pronier, and mostly to the amazing scientist and human being who led this project @facuumm.bsky.social
#neuroskyence #hippocampus
www.nature.com/articles/s41...

Very excited to share new work by Leonardo Lupori. In mice, a single dose of the antipsychotic clozapine results in changes to behavior and cortical activity patterns that remain detectable a week later.
www.biorxiv.org/content/10.6...

Check out our new preprint and learn about the smart foraging behavior of fly larvae!
www.biorxiv.org/content/10.6...

Graphical abstract showing that NMDAR immunisation drives psychosis-like behaviour in mice, while clozapine reverses this. Upper panel: arrows show NMDAR immunisation producing a mouse exhibiting psychosis-like behaviour, with clozapine reversing this effect. Lower panels: anti-NMDAR antibodies bind neuronal NMDA receptors, which are then eliminated by microglia via phagocytosis, leading to psychosis. Clozapine restores NMDA receptor levels by reducing anti-NMDAR antibody levels, consistent with an immunomodulatory mechanism of action.

🥁🎉The Psychosis Collective proudly presents our first preprint

𝐂𝐥𝐨𝐳𝐚𝐩𝐢𝐧𝐞 𝐬𝐮𝐩𝐩𝐫𝐞𝐬𝐬𝐞𝐬 𝐚𝐮𝐭𝐨𝐢𝐦𝐦𝐮𝐧𝐢𝐭𝐲 𝐝𝐫𝐢𝐯𝐢𝐧𝐠 𝐩𝐬𝐲𝐜𝐡𝐨𝐬𝐢𝐬-𝐥𝐢𝐤𝐞 𝐛𝐞𝐡𝐚𝐯𝐢𝐨𝐮𝐫 𝐢𝐧 𝐦𝐢𝐜𝐞

𝘈 𝘥𝘪𝘴𝘤𝘰𝘷𝘦𝘳𝘺 𝘫𝘰𝘶𝘳𝘯𝘦𝘺 𝘪𝘯 𝘵𝘩𝘳𝘦𝘦 𝘢𝘤𝘵𝘴

starring Le He & Harriet Feldman

www.biorxiv.org/content/10.6...

We wanted to understand how antipsychotics work. Thread🧵

A fantastic course you don’t want to miss! The application deadline has been extended to April 13.

Thank you so much

thank you so much! so kind

Thank you so much. That’s very kind. And thank you for all your support along the way