Natural maternal immunity protects neonates from Escherichia coli sepsis Nature - Neonatal sepsis caused by Escherichia coli is associated with reduced transfer of pathogen-specific maternal antibodies and, in a mouse model, can be prevented by maternal preconceptual...

rdcu.be/fasPF

It’s a mom’s nature to protect her child! Here is exciting evidence showing Mom’s E.coli protection! @babiesresearch.bsky.social

Maternal Krüppel-like factor 2 (KLF2)+ CD4 T cells promote fertility and fetal tolerance | PNAS Pregnancy requires expanded maternal tolerance to semiallogeneic fetal-expressed antigens to protect against fetal loss and other pregnancy complic...

Learning new pathways of fetal tolerance! Maternal Krüppel-like factor 2 (KLF2)+ CD4 T cells promote fertility and fetal tolerance | PNAS www.pnas.org/doi/10.1073/...
@babiesresearch.bsky.social

Immune suppression sustained allograft acceptance requires PD1 inhibition of CD8+ T cells Abstract. Organ transplant recipients require continual immune-suppressive therapies to sustain allograft acceptance. Although medication nonadherence is a

Immune suppression sustained allograft acceptance requires PD1 inhibition of CD8+ T cells
doi.org/10.1093/jimm...
@cincyresearch.bsky.social @hilmill1113.bsky.social @jimmunol.bsky.social

Donor‐Derived Infections: Transplant Infectious Disease: Vol 26, No S1 Click on the title to browse this issue

So excited to have the Donor-Derived Infection Special Edition out - thanks to Stephanie Pouch and Karen Waller for being guest editors for this special edition!

onlinelibrary.wiley.com/toc/13993062...

Science’s 2024 Breakthrough of the Year is lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months. The drug attaches to the lattice-like capsid proteins that shield the virus’s genetic material—a mechanism that could inspire other antivirals. Lenacapavir could help end the HIV/AIDS epidemic, but that will hinge on access for those who need it most.

Science’s 2024 Breakthrough of the Year is lenacapavir, an injectable drug that demonstrated remarkable success at preventing HIV infection with one shot every 6 months.

Learn more about this year's #BOTY and other big advances in science: scim.ag/3BrCtUn