Chromosome length is not the sole determinant of sexually dimorphic crossover rates during mammalian meiosis: Insights from genetically diverse mouse strains Meiotic recombination generates crossovers (COs), reciprocal exchanges between homologous chromosomes critical for accurate chromosome segregation. Inappropriate CO frequency and distribution drive an...

So excited to finally share my recent work on sex differences in crossing over using mice from diverse genetic backgrounds!
www.biorxiv.org/content/10.6...

Finally! I missed the last one, but I'm desperate to go back!

Huge congratulations to Dr. @awood2.bsky.social on her successful defense!!! So proud of you and all you've accomplished!

It's my favorite place in the country. I'm tempted to only seek out jobs in NM.

I miss the desert

I'm counting hundreds of tiny green dots, streaming triple j's "like a version" and pretending I'm still in Adelaide (where it is now summer, and things and wonderful).

Just now?

Glad to see I'm not the only one making this joke

Weaned and ear-tagged some PWD mice recently (if you know, you know how...energetic they can be). Parents were bouncing off the walls, but the babies are perhaps the sweetest little mice I've ever met.

Fig. 1. Dynamic sex variability - An integrative, multidimensional framework. A framework that centers sex variability will enable the study of sex across multiple levels of biological analysis (colored boxes). A) Visual schematic representing the degree of sex variability (y-axis) across biological scale (x-axis) and time (z-axis), with example sex variables of interest (not all possible covariates and functional relationships are presented). In this example, to decipher mechanisms linking gonadal hormones to receptive reproductive behavior in adult rodents (lordosis), the functional relationships (black subset of possible gray relationships) between select variables (bold words) need to be identified. At each level of analysis, numerous variables differ across sex to contribute to reproductive behavior through these functional interactions. Importantly, the degree of variability across sex categories is dynamic and is affected by developmental stage, experience, and environment.

Fig. 2. Approaches for the statistical analysis of sex-associated traits. Flow chart of example approaches for analyzing datasets with sex-associated variables. These analyses answer questions about whether and how sex-associated variables explain variation in dependent variables of interest, how independent variables of interest explain variation in dependent sex-associated variables, and how sex-associated variables (within and/or across levels of analysis) relate to one another. The examples match those in the text where possible, but the approaches are widely applicable and flexible. The choice(s) of analyses should follow directly from the research question(s), and it is likely that multiple approaches will be used in the analysis of an integrative dataset.

Fig. 3. Questions for evaluating frameworks and approaches which study sex variability and diversity. Here, we present a set of questions to ask when critically evaluating work (whether it is your own or others) that addresses sex diversity and variability. Note that these questions reflect the integration of the conceptual framework, experimental approaches, and analysis and interpretation, as each of these aspects informs the other.

The sex binary is dead!
Long live sex diversity & variability!

Sex is one of the greatest sources of variation seen in life. How do we advance the scientific study of sex across the animal kingdom? Read our latest article in Hormones & Behavior to find out!

🧪 🧠 #neuroskyence

You put your ID and keys on a carabiner hooked to your belt and lean into it as part of a lesbian aesthetic

Probably the latter. 😔

Should I go to Ithaca's premature Trans Day of Remembrance? Probably. Will I? No. Why? Because I am trash.

Is it oily or does it have rabies? If you're (un)lucky enough: both!

Very sad/upset about leaving NM a week early, never having made it to Las Cruces. A handful of days in Albuquerque was not sufficient; I need to come back asap.

This is such a staggeringly accurate comparison 😂

I'm getting frustrated at how heavily my research relies on antibodies, yet how few quality antibodies are actually available. There has to be a better way.

In that it is currently October? Yes, I suppose it is the month for another 30 days...

Why did I ever stop studying monotremes? Easily a top 5 lifetime regret.

I've been stuck with B for the last 3+ years, and not a day goes by I don't wish I had A

Metazooa Become an evolutionary detective to find the Mystery Animal!

I've found an excellent new way to spend time between washes/incubations: metazooa.com