Machine learning reveals genes impacting oxidative stress resistance across yeasts - Nature Communications Yeasts are exposed to oxidative stress during routine metabolism, bioproduction, and interactions with other organisms. Here, the authors use a machine learning classifier to identify genes that are p...

Very happy to share our new paper on how machine learning predicts gene family expansions which contribute to oxidative stress resistance across diverse yeast species:

www.nature.com/articles/s41...

Ancient co-option of LTR retrotransposons as yeast centromeres The evolutionary origins of the genetic point centromere in the brewer's yeast Saccharomyces cerevisiae, a member of the order Saccharomycetales, are still unknown. Competing hypotheses suggest that t...

It’s out! The evolutionary origins of yeast point centromeres uncovered!

“Ancient co-option of LTR retrotransposons as yeast centromeres”

www.biorxiv.org/content/10.1...

Please tell us all about it

Two mycologists profiled here discussing the enormous recent changes in their careers 🍄‍🟫🍄💔

Excited to share our latest paper, now online in Molecular Cell. First, it shows that the RNAPII-CTD kinases CDK9 and CDK12 are Ser5-Ser2 kinases. Secondly, it describes the activation mechanism of CDK12/13 by PAF1C complex. Congratulations to David López Martínez and coauthors!
lnkd.in/d_nbfMht

Amazing work

In our new paper, we uncover a damaged chromatin marking mechanism that drives the non-random segregation of UV damage through mitosis. Chromatin alterations impinge on genome stability by controlling DNA damage segregation
See Ferrand*, Dabin* et al., Nat Commun 2025.

Janevska @slavi-jan.bsky.social et al engineered an Aspergillus nidulans chassis for psilocybin production by repressing L-tryptophan catabolism. Deleting aminotransferase genes aroH1 and aroH2 led to a 10-fold increase in psilocybin yield. Read ➡️ https://buff.ly/4g8VutI

Pangenome graph analysis reveals extensive effector copy-number variation in spinach downy mildew Author summary Plant pathogens are known to evolve rapidly and overcome disease resistance of newly introduced crop varieties. This swift adaptation is visible in the genomes of these pathogens, which...

This is a wonderful paper by @mfseidl.bsky.social and colleagues doi.org/10.1371/jour...