Accelerated maturation of antiviral T cell immunity in children living with HIV despite antiretroviral therapy #SingleCell 🧪🧬🖥️
www.researchsquare.com/article/rs-9357619/lates...

Organelle partitioning in the multi-budding yeast Aureobasidium pullulans #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Integrated Single-Cell and Spatial Profiling of MMP Gene Expression in Colorectal Cancer #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Plectin promotes an aggressive phenotype and represses cytotoxic T cell activity in pancreatic cancer #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Interaction between TREM2-Macrophages and Cutibacterium acnes Drives Altered Lipid Metabolism in Chronic Apical Periodontitis #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Geometric coherence of single-cell CRISPR perturbations reveals regulatory architecture and predicts cellular stress #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2604.16642

Generative AI-assisted Bayesian-frequentist Hybrid Inference in Single-cell RNA Sequencing Analysis for Genes Associated with Alzheimer's Disease #SingleCell 🧪🧬🖥️
www.medrxiv.org/content/10.64898/2026.04...

Posterior parietal cortex guides sensorimotor associative learning by linking sensation to distal action #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Generation and long-term expansion of human pancreatic islet organoids in vitro #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Single-cell brain expression–guided causal analysis identifies GFM1 as a protective factor in insomnia risk #SingleCell 🧪🧬🖥️
www.researchsquare.com/article/rs-9371633/lates...

BeamMap: Beam Enabled Accurate Mapping and Molecular Analyte Profiling for topography and biochemistry spatial correlation #SingleCell 🧪🧬🖥️
www.researchsquare.com/article/rs-8832802/lates...

PALINCODE: Recording cell lineage with ternary palindromic CRISPR bits #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Rapid functional classification of cardiac genetic variants directly informs precision cardiology #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Single-cell hit calling in high-content imaging screens with Buscar #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Scalable Posterior Uncertainty for Flexible Density-Based Clustering #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2603.03188

Resolving in vitro heterogeneity of host functional responses to HCoV-229E via single-cell analyses #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Droplet-compatible single-cell DNA methylation sequencing with PreTIC #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Coordinated Tuning of Ionizable Lipids and Formulation Redirects mRNA Vaccines Toward Lymphoid-Specific CD4+ T Cell Immunity #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Mapping breast cancer lineage in radiation and immunotherapy using the REMAP mouse #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Dynamic regulation of long non-coding RNAs across asexual andgametocyte development in Plasmodium falciparum #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

cellNexus: Quality control, annotation, aggregation and analytical layers for the Human Cell Atlas data #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

MIOFlow 2.0: A unified framework for inferring cellular stochastic dynamics from single cell and spatial transcriptomics data #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2603.22564

Structure as Computation: Developmental Generation of Minimal Neural Circuits #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2604.15143

Intermediate Layers Encode Optimal Biological Representations in Single-Cell Foundation Models #SingleCell 🧪🧬🖥️
https://arxiv.org/abs/2604.14838

An Endocytic Checkpoint Controls Macrophage PD-1 Function and Immunotherapy Fate #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

An integrated pipeline to count individual transcripts with single-cell resolution #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Expansion and Differentiation of Adult Human Pancreas-Derived Progenitor Cells into Functional Islet-Like Organoids #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Functional PD-1/PD-L1 engagement defines a spatial biomarker of immunotherapy response #SingleCell 🧪🧬🖥️
www.medrxiv.org/content/10.64898/2026.04...

Comprehensive single cell profiling of ageing glial cells reveals impaired Wnt signalling and Jun transcription factors regulating cortical astrocytes #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...

Engineering autologous ossicles for the personalized modeling of acute myeloid leukemia #SingleCell 🧪🧬🖥️
www.biorxiv.org/content/10.64898/2026.04...