Brain chemistry reveals psychiatry’s false divisions – new study Dopamine clues reveal a common thread in psychosis.

Dopamine clues reveal a common thread in psychosis.

So what?
Fair points- limbic selectivity for mood psychoses mapping onto therapeutic agents, and transdiagnostic approaches for positive symptoms?
I will take that, though happy for critique!

DA lowers in ppl w psychosis and MDE than ppl w mania (esp Mesolimbic system)
DA correlated w positive sx, across diagnoses (esp associative striatum)
Take home?
Symptoms track biology as opposed to diagnoses, though differences still exist across disorders.

Answers-look at the Figures, see what you think

We used PET to examine dopamine synthesis in ppl w psychosis and mood disorders.
2 questions:
i) Is DA reduced in ppl w psychosis+ major depressive episode?

ii) Is there a relationship between DA and positive psychotic sx (delusions and hallucinations) across affective psychoses?

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