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Posts by E John Wherry

A very special thanks to Dr. Vera Moiseenkova-Bell and Dr. John Wherry @ejohnwherry.bsky.social for their extraordinary support in making this happen.

6 months ago 6 1 0 0
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The Man Behind Trump’s Push for an All-Powerful Presidency

www.nytimes.com/2025/09/29/u...

6 months ago 4 0 0 0
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David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87

What a huge loss. I am so sorry to hear this news. David was a tremendous positive presence across all biomedical science. A once in a generation kind of scientist. www.nytimes.com/2025/09/07/s...

7 months ago 10 3 0 0
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Yesterday we opened a new home for Immunology at Penn. Part of our large vibrant immunology community will move into this amazing space. This includes our #ColtonCenter for Autoimmunity, #ImmuneHealth and more.

youtu.be/Ryv2AxPtb_E?...

7 months ago 22 0 1 0
The Power of Public Investment in Science
The Power of Public Investment in Science YouTube video by Penn Medicine

youtu.be/px__ULMCnLM?...

7 months ago 5 2 1 0
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CHOP, Wistar and other Philly-area research institutions urge legislators to reject NIH cuts The Pennsylvania Ad Hoc NIH Funding Advocacy Coalition brings together institutions from across the state’s eds and meds sector.

Great article in the @inquirer.com om about the importance of NIH funding. www.inquirer.com/health/medic...

8 months ago 3 0 0 0
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A World Without Academic Medicine 2025 This is "A World Without Academic Medicine 2025" by AAMC on Vimeo, the home for high quality videos and the people who love them.

vimeo.com/1103907156/4...

8 months ago 2 1 0 0
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Divergent ontogeny of Tissue Resident Memory and Tissue Resident Exhausted CD8+ T cells underlies distinct functional potential Persistent antigen stimulation promotes differentiation of exhausted CD8+ T (TEX) cells. TEX cells are distinct from circulating memory T (TCIRCM) cells but share many features with tissue-resident me...

What's the difference between Trm and exhausted CD8 T cells? Simone Park's new work dissects this important question. These cell types are often confused, but are ontologically and mechanistically distinct with implications for immunotherapy responses. www.biorxiv.org/content/10.1...

8 months ago 32 6 0 0
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Long COVID and Other Post-Acute Infection Syndromes | Keystone Symposia Join us at the Keystone Symposia on Long COVID and Other Post-Acute Infection Syndromes, August 2025, in Santa Fe, with field leaders!

A great Keystone meeting on Long COVID this week in Santa Fe. The field has made great progress recently, but there is much more to do. Exciting science presented about viral and immune mechanisms, clinical data and future clinical trials. www.keystonesymposia.org/conferences/...

8 months ago 17 3 1 0
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Ozzy Osbourne was an agent of darkness and a beloved family man alike. “This cognitive dissonance is precisely why he was regarded as a titan,” Spencer Kornhaber writes: https://theatln.tc/7b1rHz12

8 months ago 62 7 4 0
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More Everything Forever: AI Overlords, Space Empires, a… How Silicon Valley’s heartless, baseless, and foolish o…

Highly recommend this book
www.goodreads.com/book/show/21...

8 months ago 4 0 0 0

RIP Ozzy!!!

8 months ago 6 0 0 1
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Researchers crack the code of body’s ancient immune defense | Penn Today A collaborative team from Penn Medicine and Penn Engineering have  unraveled the mathematics of a 500-million-year-old protein network that “decides” which foreign materials are friend or foe.

penntoday.upenn.edu/news/researc...

10 months ago 6 1 0 0
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I’ve been in academic medicine for 45 years. This is the first time I’m seeing a perfect storm, as proposed federal funding cuts threaten our ability to provide patient care, train the next generation of doctors, and conduct life-saving research. More from my conversation with @cnn.com last week.

10 months ago 2371 870 77 41
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A useful distraction this weekend....

10 months ago 4 0 0 0
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A Path Forward to Save American Bio-Medical Research Over the past four months I’ve spoken to dozens of biomedical researchers...

A Path Forward to Save American Bio-Medical Research talkingpointsmemo.com/edblog/a-pat...

11 months ago 626 239 23 53
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World’s first personalized CRISPR therapy given to baby with genetic disease Treatment seems to have been effective, but it is not clear whether such bespoke therapies can be widely applied.

To be clear, these kinds of breakthroughs are going to come to a screeching halt with the current NIH funding cuts. This new treatment is only possible because of decades of basic research. What might be possible 20 years from now if we don't destroy basic research?

www.nature.com/articles/d41...

11 months ago 129 52 0 1
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Trump Administration Live Updates: Supreme Court Extends Freeze on Use of Alien Enemies Act for Deportations

Breaking News: Moody’s has downgraded the credit rating of the U.S., becoming the third major credit rating agency to downgrade the country since 2011.

11 months ago 596 182 56 40

Word.
“The future of biomedical research in the United States comes down to a race to see whether the biomedical research community can mobilize politically, access that vast but latent political power, before the White House can do enough sustained damage to make the whole question moot.”

11 months ago 488 124 6 4

RFK Jr. said multiple times during his house and senate hearings today that no scientists have been fired from federal agencies. Our reporting has shown that hundreds, if not thousands, of scientists have been let go from NIH/CDC/FDA

11 months ago 15474 5046 587 300
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Trump Is Poised to Accept a Luxury 747 From Qatar for Use as Air Force One

So this is not a problem?...But we can't even buy an NIH researcher a cup of coffee because of conflicts of interest!? The hypocrisy is insane. Investigations into universities, but at the White House all gifts and straight up crypto-bribes are fine. WTF www.nytimes.com/2025/05/11/u...

11 months ago 19 4 0 0
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Congrats to @ejohnwherry.bsky.social, PhD—pioneer of T cell exhaustion and checkpoint biology—on his election to the National Academy of Sciences. A well-earned honor for work that continues to drive immunotherapy forward.

www.nasonline.org/news/2025-na...

#NAS2025

11 months ago 21 2 0 0
How Uncertainty About Federal Support for Science Impacts You and Your Institution

Use this link to write to your representatives as often as possible!!
secure.everyaction.com/1ExSmGrI2kqH...

11 months ago 9 5 1 0
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Dr. Anthony Fauci urges Americans not to accept "Normalization of Untruths".

11 months ago 45378 12440 1039 674

Congratulations to @ejohnwherry.bsky.social and Penn colleagues, Katalin Karikó, Virginia Lee (@pennpathlabmed.bsky.social) and Mark Devlin on being elected as members of the @nasonline.org—one of the highest honors a scientist can receive!

11 months ago 13 1 0 0
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Congratulations to Katalin Karikó (@PennNSG), Virginia Lee (@pennpathlabmed.bsky.social), @ejohnwherry.bsky.social (@PennSysPharmATT) & Mark Devlin (@physatpenn) on their election to @nasonline.org! tinyurl.com/5eehdtms

11 months ago 16 7 0 1
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National Academy of Sciences Elects Members and International Members - NAS WASHINGTON — The National Academy of Sciences announced today the election of 120 members and 30 international members in recognition of their distinguished and continuing achievements in original res...

Honored and humbled. I have been very fortunate to have worked with amazing, inspirational colleagues in my lab, at Penn and in the broader community. Science matters
www.nasonline.org/news/2025-na...

11 months ago 110 8 26 1
RFK Jr. & HHS: Last Week Tonight with John Oliver (HBO)
RFK Jr. & HHS: Last Week Tonight with John Oliver (HBO) YouTube video by LastWeekTonight

Very accurate
youtu.be/8H34jcpEsFs?...

11 months ago 15 7 0 0

Congratulations to all of the new National Academy of Sciences members!! Special shout out to @ejohnwherry.bsky.social and Eric Skaar!!! So well deserved!

11 months ago 24 4 1 0
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National Academy of Sciences Elects Members and International Members - NAS WASHINGTON — The National Academy of Sciences announced today the election of 120 members and 30 international members in recognition of their distinguished and continuing achievements in original res...

Congratulations to all the new members especially @ejohnwherry.bsky.social! National Academy of Sciences Elects Members and International Members - NAS www.nasonline.org/news/2025-na...

11 months ago 4 1 0 0