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Posts by Antho Leon

Check out last preprint and keep tuned for more ;)

2 days ago 2 0 0 0
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Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and re-patterning of snRNA m6A modification In eukaryotes, splicing is a critical step of gene expression that produces transcripts competent for protein synthesis by removing introns from pre-mRNA. The spliceosome defines target splice sites b...

Check the last preprint from @simonhenriet.bsky.social & colleaguesโ€ฌ. By studying appendicularians, they revealed the events that permitted non-canonical splicing in these organisms:

. Duplication & divergence of U2AF splicing factors
. Gain & loss of chemical modifications on the spliceosomal RNA

8 months ago 9 4 0 1