Modern lights on neuropathology of Alzheimer’s Disease Ludovic S Mure; Modern lights on neuropathology of Alzheimer’s Disease, Sleep, , zsag080, https://doi.org/10.1093/sleep/zsag080

#Circadian disruption is well linked to Alzheimer’s disease but how does it shape pathology?
In this invited editorial in SLEEP, I discuss Duncan et al.’s study showing that dim light at night reshapes microglial state and amyloid vulnerability.
#Alzheimers #LightPollution
shorturl.at/BJzTE

🔔 Our latest special issue, guest edited by Prof. Carrie Partch, is now live! Featuring:

⏰ The latest advances in our understanding of the molecular basis of circadian rhythms
⏱️ Circadian rhythms' pervasive and powerful control of biology
⌚ And — new frontiers in the field.

▶️ tinyurl.com/3a7nr7je

Your smart speaker?

Interested in the effects of the time change in our bodies and brain? Participate in a Canadian study here. www.facebook.com/share/p/18Nc...

Ten year survival in breast cancer patients TimeTeller predicted good or bad clock function shows good clock function is associated with shorter survival.

Good clocks are bad? Using TimeTeller we predict clock function and phase from breast tumour transcriptomes in a multi-cohort dataset including 1286 patients. We find that good tumour clock function is antagonistic to survival.
Now out as preprint: Vasilyev et al.
www.biorxiv.org/content/10.6...

News (All) | Bioclocks Uk

Satellites could disrupt #circadian rhythms globally. Major projects such as #ReflectOrbital and #SpaceX are pushing boundaries, and now is the time to recognise the effect these projects could have on life everywhere. www.bioclocks.uk/news
🧪 #AcademicSky #Scicomm #Chronobiology

if you are looking for a German word again, basically "Götterdämmerung"?

2026 off to a heavy start. Very sad news from Hanover: The European circadian and seasonal rhythms community lost an excellent physiologist and a genuinely kind human being. Stephan Steinlechner passed away unexpectedly in January.
tinyurl.com/stephanstein...

Feeding-regulated glycogen metabolism drives rhythmic liver protein secretion - Nature Metabolism Hepatic glycogenolysis is essential for protein glycosylation and rhythmic secretion by the liver. Disruptions to hepatic glycogenolysis, caused by congenital diseases or physiological factors such as...

Very happy to see this work published!

The result of 10 years of research across Switzerland, Australia and Denmark!

#Circadian #chronobiology
@melweger.bsky.social @benweger.bsky.social @danielmauvoisin.bsky.social @robparton.bsky.social @benschulz.bsky.social

www.nature.com/articles/s42...

The time of day for cancer immunotherapy is associated with major outcomes. Early is better. Results from a randomized trial of lung cancer, backs up the importance of our circadian rhythm and immune system
www.nature.com/articles/s41...

The Onion finally gets around to sleep studies.

4 year post doc post at Maynooth in Human Sleep and Respiratory Physiology.
universityvacancies.com/maynooth-uni...

Daily ultrastructural remodeling of clock neurons A cluster of Drosophila clock neurons remodel their axonal arbors daily. Using volumetric electron microscopy at different times of day, Ispizua, Rodriguez-Caron, and colleagues reveal ultrastructural...

SO HAPPY to share our new paper in @currentbiology.bsky.social! Using volumetric EM, we found daily shifts in synapses, vesicles, and mitochondria that accompany neuronal remodeling, linking structural plasticity to changes in how s-LNv neurons influence their targets
www.cell.com/current-biol...

My SWBio PhD DTP project with Lukasz Chrobok (@chroboklab.bsky.social) and Kate Elliott (@neuroendo.bsky.social) is now advertised:

Run, sleep, repeat: Regular exercise for good health and longevity.

bpb-eu-w2.wpmucdn.com/blogs.bristo...

Fresh off the press. Just flagging up a short opinion piece I wrote for Bioessays about astrocytes in sleep and circadian rhythms. It has been fun to write it! @circadiageing.bsky.social @imperialbrains.bsky.social

onlinelibrary.wiley.com/doi/epdf/10....

4yr MRC-funded postdoc position investigating circadian mechanisms in cardiometabolic disease, currently available @manchester.ac.uk

www.jobs.manchester.ac.uk/Job/JobDetai...

Come and join our brilliant Centre for Biological Timing team!

@bioclocksuk.bsky.social #chronobiology #circadian #postdoc

Closing date: November 17, 2025.

Beginning of Faust I

Excited to join the #UnderOneSky conference (Nov 7–8), organized by @darkskyintl.bsky.social to protect our natural night. 🌙

I’ll present findings from the ENLIGHT project on how #lightpollution affects amphibians, highlighting why preserving natural night conditions is vital for wildlife.

Socioeconomic roots of academic faculty - Nature Human Behaviour Studying socioeconomic backgrounds and intergenerational transmission in the US academia, Morgan et al. find that faculty have a parent with a Ph.D. degree a striking 25 times more often than the gene...

Socioeconomic roots of academic faculty

Tenure-track faculty are up to 25 times more likely to have a parent with a Ph.D. Moreover, this rate nearly doubles at prestigious universities and is stable across the past 50 years.

#AcademicSky

Personalizing chronotherapy of immune checkpoint blockade Emerging evidence highlights the critical role of time-of-day (ToD) in immunotherapy, with large-scale retrospective studies showing that administering immune checkpoint inhibitors (ICIs) earlier in t...

Led by Seline Ismail-Sutton, our response on the excellent recent piece by Özdemir et al. how to prevent the low hanging fruit being rotten in chrono-immunotherapy. doi.org/10.1136/jitc...

Do you have an extra central service charge for a leisure pool in the office?

A functional clock in only two dorsal clock neurons is sufficient to restore the basal circadian activity pattern of Drosophila melanogaster | PNAS Circadian clocks form complex networks to orchestrate the behavior and physiology of animals. Elucidating the organization of these clock networks ...

A functional clock in only two dorsal clock neurons is sufficient to restore the basal circadian activity pattern of Drosophila melanogaster | PNAS www.pnas.org/doi/10.1073/...

Canonical correlation analysis reveals five sleep-biopsychosocial profiles (LCs). Scatter plots showing correlations between biopsychosocial and sleep canonical scores. Each dot represents a different participant. The inset shows the null distribution of canonical correlations obtained by permutation testing; note that the null distribution is not centered at zero. The dashed line indicates the actual canonical correlation computed for each LC. The distribution of sleep (top) and biopsychosocial (right) canonical scores is shown on rain cloud plots.

Sleep is often only investigated from a single dimension. @bttyeo.bsky.social &co identify 5 sleep-biopsychosocial profiles that link self-reported #sleep patterns to variability in #health, #cognition & #lifestyle factors in 770 healthy young adults @plosbiology.org 🧪 plos.io/42tRXSc

BBC Radio 4 - You're Dead to Me, The History of Timekeeping Join Greg Jenner at the literal beginning of time to explore the history of timekeeping.

The clocks go back tonight, which is my perfect excuse to share my fave episode of BBC You’re Dead To Me about the History of Timekeeping (from 2022)

www.bbc.co.uk/programmes/p...

What’s the cap on human energy expenditure? Elite athletes reveal ‘metabolic ceiling’ When athletes devote large amounts of energy to running or cycling, they unconsciously cut back on energy output elsewhere.

There seems to be a limitation for elite athletes, might well be, www.nature.com/articles/d41...
but have they tested the proposed energy cap in 10-year old children? From own experience, I have doubts they are limited like this! doi.org/10.3389/fphy...

Interested in unconventional signalling pathways from membrane proteins and how they connect membrane protease function, gene regulation, and disease pathology?

I'm offering a PhD project via MIBTP & MRC-DTP(warwick.ac.uk/fac/sci/med/...) programmes
@warwicklifesci.bsky.social
Apply now for 2026!

Online Flipbook Created with the Heyzine flipbook maker

Find out what the UK #chronobiology community has been up to and how we're working to bring science out of the lab in our newsletter:
heyzine.com/flip-book/a3...

DDR plante eigene Zeit: Zeitumstellung in Ost und West | MDR.DE Es wird wieder mal an der Uhr gedreht! 1980 stellte auch die DDR erstmals die Uhr um. Doch kaum einer ahnte, dass der Wechsel aus Sommer- und Winterzeit eine Eiszeit zwischen den beiden deutschen Staa...

Gerade gelernt: die Sommerzeit hat die DDR der Bundesrepublik rein gedrückt.
Im Osten war das allerdings als Experiment gedacht und sollte nach einem Jahr wegen Misserfolg wieder abgeblasen werden. Da stellte man sich im Westen dann quer. Das Abblasen wurde abgeblasen.

BBC Radio 4 - In Our Time, Circadian Rhythms Melvyn Bragg and guests discuss circadian rhythms.

Around the equinox, we see an increased interest in how biological rhythms are affected by light. UK #Chronobiology academics have been communicating the research on this for over a decade now - check out this timeless podcast episode on rhythms: www.bbc.co.uk/programmes/b...
#SciComm 🧪